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Solubility-driven optimization of phosphodiesterase-4 inhibitors leading to a clinical candidate.
Press NJ, Taylor RJ, Fullerton JD, Tranter P, McCarthy C, Keller TH, Arnold N, Beer D, Brown L, Cheung R, Christie J, Denholm A, Haberthuer S, Hatto JD, Keenan M, Mercer MK, Oakman H, Sahri H, Tuffnell AR, Tweed M, Tyler JW, Wagner T, Fozard JR, Trifilieff A. Press NJ, et al. Among authors: cheung r. J Med Chem. 2012 Sep 13;55(17):7472-9. doi: 10.1021/jm300459a. Epub 2012 Aug 30. J Med Chem. 2012. PMID: 22889281
A new orally bioavailable dual adenosine A2B/A3 receptor antagonist with therapeutic potential.
Press NJ, Taylor RJ, Fullerton JD, Tranter P, McCarthy C, Keller TH, Brown L, Cheung R, Christie J, Haberthuer S, Hatto JD, Keenan M, Mercer MK, Press NE, Sahri H, Tuffnell AR, Tweed M, Fozard JR. Press NJ, et al. Among authors: cheung r. Bioorg Med Chem Lett. 2005 Jun 15;15(12):3081-5. doi: 10.1016/j.bmcl.2005.04.021. Bioorg Med Chem Lett. 2005. PMID: 15876531
Discovery and Optimization of 4-(8-(3-Fluorophenyl)-1,7-naphthyridin-6-yl)transcyclohexanecarboxylic Acid, an Improved PDE4 Inhibitor for the Treatment of Chronic Obstructive Pulmonary Disease (COPD).
Press NJ, Taylor RJ, Fullerton JD, Tranter P, McCarthy C, Keller TH, Arnold N, Beer D, Brown L, Cheung R, Christie J, Denholm A, Haberthuer S, Hatto JD, Keenan M, Mercer MK, Oakman H, Sahri H, Tuffnell AR, Tweed M, Trifilieff A. Press NJ, et al. Among authors: cheung r. J Med Chem. 2015 Sep 10;58(17):6747-52. doi: 10.1021/acs.jmedchem.5b00902. Epub 2015 Aug 28. J Med Chem. 2015. PMID: 26288344
Relationship between trait mindfulness and physical activity among emerging adults: The mediating roles of exercise-related cognitive errors and trait self-control.
Yuan D, Kuang J, Li J, Cheung RYM, Herold F, Gerber M, Taylor A, Kramer AF, Wang J, Yeung AS, Zou L. Yuan D, et al. Among authors: cheung rym. Complement Ther Clin Pract. 2025 Jan 18;59:101953. doi: 10.1016/j.ctcp.2025.101953. Online ahead of print. Complement Ther Clin Pract. 2025. PMID: 39837156
Online Measurements during Simulated Atmospheric Aging Track the Strongly Increasing Oxidative Potential of Complex Combustion Aerosols Relative to Their Primary Emissions.
Cheung RKY, Zhang J, Wang T, Kattner L, Bogler S, Puthussery JV, Huang RJ, Gysel-Beer M, Slowik JG, Verma V, Prevot ASH, El Haddad I, Bell DM, Modini RL. Cheung RKY, et al. Environ Sci Technol Lett. 2024 Dec 10;12(1):64-72. doi: 10.1021/acs.estlett.4c00956. eCollection 2025 Jan 14. Environ Sci Technol Lett. 2024. PMID: 39830725 Free PMC article.
Comparison of Referral Rates and Costs Using Fibrosis-4 and Enhanced Liver Fibrosis (ELF) Testing Strategies for Initial Evaluation of Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) in a Veteran Population.
Yeramaneni S, Chang ST, Cheung RC, Chalfin DB, Sangha K, Levy HR, Boltyenkov AT. Yeramaneni S, et al. Among authors: cheung rc. J Appl Lab Med. 2025 Jan 15:jfae154. doi: 10.1093/jalm/jfae154. Online ahead of print. J Appl Lab Med. 2025. PMID: 39812398
1,126 results