Chien AJ - Search Results

1

Regulating the response to targeted MEK inhibition in melanoma: enhancing apoptosis in NRAS- and BRAF-mutant melanoma cells with Wnt/β-catenin activation.

Conrad WH, Swift RD, Biechele TL, Kulikauskas RM, Moon RT, Chien AJ. Conrad WH, et al. Among authors: chien aj. Cell Cycle. 2012 Oct 15;11(20):3724-30. doi: 10.4161/cc.21645. Epub 2012 Aug 16. Cell Cycle. 2012. PMID: 22895053 Free PMC article.

2

WNTS and WNT receptors as therapeutic tools and targets in human disease processes.

Chien AJ, Moon RT. Chien AJ, et al. Front Biosci. 2007 Jan 1;12:448-57. doi: 10.2741/2074. Front Biosci. 2007. PMID: 17127309 Free PMC article. Review.

3

CTLA-4 is a direct target of Wnt/beta-catenin signaling and is expressed in human melanoma tumors.

Shah KV, Chien AJ, Yee C, Moon RT. Shah KV, et al. Among authors: chien aj. J Invest Dermatol. 2008 Dec;128(12):2870-9. doi: 10.1038/jid.2008.170. Epub 2008 Jun 19. J Invest Dermatol. 2008. PMID: 18563180 Free PMC article.

4

Activated Wnt/beta-catenin signaling in melanoma is associated with decreased proliferation in patient tumors and a murine melanoma model.

Chien AJ, Moore EC, Lonsdorf AS, Kulikauskas RM, Rothberg BG, Berger AJ, Major MB, Hwang ST, Rimm DL, Moon RT. Chien AJ, et al. Proc Natl Acad Sci U S A. 2009 Jan 27;106(4):1193-8. doi: 10.1073/pnas.0811902106. Epub 2009 Jan 14. Proc Natl Acad Sci U S A. 2009. PMID: 19144919 Free PMC article.

5

Wnt/Fz signaling and the cytoskeleton: potential roles in tumorigenesis.

Lai SL, Chien AJ, Moon RT. Lai SL, et al. Among authors: chien aj. Cell Res. 2009 May;19(5):532-45. doi: 10.1038/cr.2009.41. Cell Res. 2009. PMID: 19365405 Review.

6

A re-evaluation of the "oncogenic" nature of Wnt/beta-catenin signaling in melanoma and other cancers.

Lucero OM, Dawson DW, Moon RT, Chien AJ. Lucero OM, et al. Among authors: chien aj. Curr Oncol Rep. 2010 Sep;12(5):314-8. doi: 10.1007/s11912-010-0114-3. Curr Oncol Rep. 2010. PMID: 20603725 Free PMC article. Review.

7

Chemical-genetic screen identifies riluzole as an enhancer of Wnt/β-catenin signaling in melanoma.

Biechele TL, Camp ND, Fass DM, Kulikauskas RM, Robin NC, White BD, Taraska CM, Moore EC, Muster J, Karmacharya R, Haggarty SJ, Chien AJ, Moon RT. Biechele TL, et al. Among authors: chien aj. Chem Biol. 2010 Nov 24;17(11):1177-82. doi: 10.1016/j.chembiol.2010.08.012. Chem Biol. 2010. PMID: 21095567 Free PMC article.

8

Wnt/β-catenin signaling and AXIN1 regulate apoptosis triggered by inhibition of the mutant kinase BRAFV600E in human melanoma.

Biechele TL, Kulikauskas RM, Toroni RA, Lucero OM, Swift RD, James RG, Robin NC, Dawson DW, Moon RT, Chien AJ. Biechele TL, et al. Among authors: chien aj. Sci Signal. 2012 Jan 10;5(206):ra3. doi: 10.1126/scisignal.2002274. Sci Signal. 2012. PMID: 22234612 Free PMC article.

9

Activation of Wnt/β-catenin signaling increases apoptosis in melanoma cells treated with trail.

Zimmerman ZF, Kulikauskas RM, Bomsztyk K, Moon RT, Chien AJ. Zimmerman ZF, et al. Among authors: chien aj. PLoS One. 2013 Jul 15;8(7):e69593. doi: 10.1371/journal.pone.0069593. Print 2013. PLoS One. 2013. PMID: 23869245 Free PMC article.

10

Targeted BRAF inhibition impacts survival in melanoma patients with high levels of Wnt/β-catenin signaling.

Chien AJ, Haydu LE, Biechele TL, Kulikauskas RM, Rizos H, Kefford RF, Scolyer RA, Moon RT, Long GV. Chien AJ, et al. PLoS One. 2014 Apr 14;9(4):e94748. doi: 10.1371/journal.pone.0094748. eCollection 2014. PLoS One. 2014. PMID: 24733413 Free PMC article.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

140 results

Search Page

Filters