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Page 1
Dendritic cells ameliorate autoimmunity in the CNS by controlling the homeostasis of PD-1 receptor(+) regulatory T cells.
Yogev N, Frommer F, Lukas D, Kautz-Neu K, Karram K, Ielo D, von Stebut E, Probst HC, van den Broek M, Riethmacher D, Birnberg T, Blank T, Reizis B, Korn T, Wiendl H, Jung S, Prinz M, Kurschus FC, Waisman A. Yogev N, et al. Among authors: wiendl h. Immunity. 2012 Aug 24;37(2):264-75. doi: 10.1016/j.immuni.2012.05.025. Epub 2012 Aug 16. Immunity. 2012. PMID: 22902234 Free article.
Smad7 in T cells drives T helper 1 responses in multiple sclerosis and experimental autoimmune encephalomyelitis.
Kleiter I, Song J, Lukas D, Hasan M, Neumann B, Croxford AL, Pedré X, Hövelmeyer N, Yogev N, Mildner A, Prinz M, Wiese E, Reifenberg K, Bittner S, Wiendl H, Steinman L, Becker C, Bogdahn U, Neurath MF, Steinbrecher A, Waisman A. Kleiter I, et al. Among authors: wiendl h. Brain. 2010 Apr;133(Pt 4):1067-81. doi: 10.1093/brain/awq039. Epub 2010 Mar 30. Brain. 2010. PMID: 20354004 Free PMC article.
Licensing of myeloid cells promotes central nervous system autoimmunity and is controlled by peroxisome proliferator-activated receptor γ.
Hucke S, Floßdorf J, Grützke B, Dunay IR, Frenzel K, Jungverdorben J, Linnartz B, Mack M, Peitz M, Brüstle O, Kurts C, Klockgether T, Neumann H, Prinz M, Wiendl H, Knolle P, Klotz L. Hucke S, et al. Among authors: wiendl h. Brain. 2012 May;135(Pt 5):1586-605. doi: 10.1093/brain/aws058. Epub 2012 Mar 24. Brain. 2012. PMID: 22447120
Blood coagulation factor XII drives adaptive immunity during neuroinflammation via CD87-mediated modulation of dendritic cells.
Göbel K, Pankratz S, Asaridou CM, Herrmann AM, Bittner S, Merker M, Ruck T, Glumm S, Langhauser F, Kraft P, Krug TF, Breuer J, Herold M, Gross CC, Beckmann D, Korb-Pap A, Schuhmann MK, Kuerten S, Mitroulis I, Ruppert C, Nolte MW, Panousis C, Klotz L, Kehrel B, Korn T, Langer HF, Pap T, Nieswandt B, Wiendl H, Chavakis T, Kleinschnitz C, Meuth SG. Göbel K, et al. Among authors: wiendl h. Nat Commun. 2016 May 18;7:11626. doi: 10.1038/ncomms11626. Nat Commun. 2016. PMID: 27188843 Free PMC article.
The farnesoid-X-receptor in myeloid cells controls CNS autoimmunity in an IL-10-dependent fashion.
Hucke S, Herold M, Liebmann M, Freise N, Lindner M, Fleck AK, Zenker S, Thiebes S, Fernandez-Orth J, Buck D, Luessi F, Meuth SG, Zipp F, Hemmer B, Engel DR, Roth J, Kuhlmann T, Wiendl H, Klotz L. Hucke S, et al. Among authors: wiendl h. Acta Neuropathol. 2016 Sep;132(3):413-31. doi: 10.1007/s00401-016-1593-6. Epub 2016 Jul 6. Acta Neuropathol. 2016. PMID: 27383204
Blockade of MCAM/CD146 impedes CNS infiltration of T cells over the choroid plexus.
Breuer J, Korpos E, Hannocks MJ, Schneider-Hohendorf T, Song J, Zondler L, Herich S, Flanagan K, Korn T, Zarbock A, Kuhlmann T, Sorokin L, Wiendl H, Schwab N. Breuer J, et al. Among authors: wiendl h. J Neuroinflammation. 2018 Aug 22;15(1):236. doi: 10.1186/s12974-018-1276-4. J Neuroinflammation. 2018. PMID: 30134924 Free PMC article.
PD-1 regulates neural damage in oligodendroglia-induced inflammation.
Kroner A, Schwab N, Ip CW, Leder C, Nave KA, Mäurer M, Wiendl H, Martini R. Kroner A, et al. Among authors: wiendl h. PLoS One. 2009;4(2):e4405. doi: 10.1371/journal.pone.0004405. Epub 2009 Feb 6. PLoS One. 2009. PMID: 19197390 Free PMC article.
753 results