Miao H - Search Results

1

A small molecule agonist of EphA2 receptor tyrosine kinase inhibits tumor cell migration in vitro and prostate cancer metastasis in vivo.

Petty A, Myshkin E, Qin H, Guo H, Miao H, Tochtrop GP, Hsieh JT, Page P, Liu L, Lindner DJ, Acharya C, MacKerell AD Jr, Ficker E, Song J, Wang B. Petty A, et al. Among authors: miao h. PLoS One. 2012;7(8):e42120. doi: 10.1371/journal.pone.0042120. Epub 2012 Aug 15. PLoS One. 2012. PMID: 22916121 Free PMC article.

2

Disruption of EphA2 receptor tyrosine kinase leads to increased susceptibility to carcinogenesis in mouse skin.

Guo H, Miao H, Gerber L, Singh J, Denning MF, Gilliam AC, Wang B. Guo H, et al. Among authors: miao h. Cancer Res. 2006 Jul 15;66(14):7050-8. doi: 10.1158/0008-5472.CAN-06-0004. Cancer Res. 2006. PMID: 16849550

3

EphA2 mediates ligand-dependent inhibition and ligand-independent promotion of cell migration and invasion via a reciprocal regulatory loop with Akt.

Miao H, Li DQ, Mukherjee A, Guo H, Petty A, Cutter J, Basilion JP, Sedor J, Wu J, Danielpour D, Sloan AE, Cohen ML, Wang B. Miao H, et al. Cancer Cell. 2009 Jul 7;16(1):9-20. doi: 10.1016/j.ccr.2009.04.009. Cancer Cell. 2009. PMID: 19573808 Free PMC article.

4

EphA receptor signaling--complexity and emerging themes.

Miao H, Wang B. Miao H, et al. Semin Cell Dev Biol. 2012 Feb;23(1):16-25. doi: 10.1016/j.semcdb.2011.10.013. Epub 2011 Oct 21. Semin Cell Dev Biol. 2012. PMID: 22040915 Free PMC article. Review.

5

EphA2 promotes infiltrative invasion of glioma stem cells in vivo through cross-talk with Akt and regulates stem cell properties.

Miao H, Gale NW, Guo H, Qian J, Petty A, Kaspar J, Murphy AJ, Valenzuela DM, Yancopoulos G, Hambardzumyan D, Lathia JD, Rich JN, Lee J, Wang B. Miao H, et al. Oncogene. 2015 Jan 29;34(5):558-67. doi: 10.1038/onc.2013.590. Epub 2014 Feb 3. Oncogene. 2015. PMID: 24488013 Free PMC article.

6

Inhibition of integrin-mediated cell adhesion but not directional cell migration requires catalytic activity of EphB3 receptor tyrosine kinase. Role of Rho family small GTPases.

Miao H, Strebhardt K, Pasquale EB, Shen TL, Guan JL, Wang B. Miao H, et al. J Biol Chem. 2005 Jan 14;280(2):923-32. doi: 10.1074/jbc.M411383200. Epub 2004 Nov 9. J Biol Chem. 2005. PMID: 15536074 Free article.

7

Eph/ephrin signaling in epithelial development and homeostasis.

Miao H, Wang B. Miao H, et al. Int J Biochem Cell Biol. 2009 Apr;41(4):762-70. doi: 10.1016/j.biocel.2008.07.019. Epub 2008 Aug 9. Int J Biochem Cell Biol. 2009. PMID: 18761422 Free PMC article. Review.

8

NMR structure of a heterodimeric SAM:SAM complex: characterization and manipulation of EphA2 binding reveal new cellular functions of SHIP2.

Lee HJ, Hota PK, Chugha P, Guo H, Miao H, Zhang L, Kim SJ, Stetzik L, Wang BC, Buck M. Lee HJ, et al. Among authors: miao h. Structure. 2012 Jan 11;20(1):41-55. doi: 10.1016/j.str.2011.11.013. Structure. 2012. PMID: 22244754 Free PMC article.

9

EPHA2 is associated with age-related cortical cataract in mice and humans.

Jun G, Guo H, Klein BE, Klein R, Wang JJ, Mitchell P, Miao H, Lee KE, Joshi T, Buck M, Chugha P, Bardenstein D, Klein AP, Bailey-Wilson JE, Gong X, Spector TD, Andrew T, Hammond CJ, Elston RC, Iyengar SK, Wang B. Jun G, et al. Among authors: miao h. PLoS Genet. 2009 Jul;5(7):e1000584. doi: 10.1371/journal.pgen.1000584. Epub 2009 Jul 31. PLoS Genet. 2009. PMID: 19649315 Free PMC article.

10

Activation of EphA2 kinase suppresses integrin function and causes focal-adhesion-kinase dephosphorylation.

Miao H, Burnett E, Kinch M, Simon E, Wang B. Miao H, et al. Nat Cell Biol. 2000 Feb;2(2):62-9. doi: 10.1038/35000008. Nat Cell Biol. 2000. PMID: 10655584

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