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In vitro metabolism of piperaquine is primarily mediated by CYP3A4.
Lee TM, Huang L, Johnson MK, Lizak P, Kroetz D, Aweeka F, Parikh S. Lee TM, et al. Among authors: huang l. Xenobiotica. 2012 Nov;42(11):1088-95. doi: 10.3109/00498254.2012.693972. Epub 2012 Jun 6. Xenobiotica. 2012. PMID: 22671777 Free PMC article.
Nevirapine inhibits the anti-HIV activity of CD8+ cells.
Liu L, Wang L, Huang L, Siu V, Teque F, Aweeka FT, Levy JA. Liu L, et al. Among authors: huang l. J Acquir Immune Defic Syndr. 2013 Jun 1;63(2):184-8. doi: 10.1097/QAI.0b013e318289822d. J Acquir Immune Defic Syndr. 2013. PMID: 23392464 Free PMC article.
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