Mahadevan D - Search Results

1

Phase I pharmacokinetic and pharmacodynamic study of the pan-PI3K/mTORC vascular targeted pro-drug SF1126 in patients with advanced solid tumours and B-cell malignancies.

Mahadevan D, Chiorean EG, Harris WB, Von Hoff DD, Stejskal-Barnett A, Qi W, Anthony SP, Younger AE, Rensvold DM, Cordova F, Shelton CF, Becker MD, Garlich JR, Durden DL, Ramanathan RK. Mahadevan D, et al. Eur J Cancer. 2012 Dec;48(18):3319-27. doi: 10.1016/j.ejca.2012.06.027. Epub 2012 Aug 23. Eur J Cancer. 2012. PMID: 22921184 Free PMC article. Clinical Trial.

2

A phase I pharmacokinetic and pharmacodynamic study of AT7519, a cyclin-dependent kinase inhibitor in patients with refractory solid tumors.

Mahadevan D, Plummer R, Squires MS, Rensvold D, Kurtin S, Pretzinger C, Dragovich T, Adams J, Lock V, Smith DM, Von Hoff D, Calvert H. Mahadevan D, et al. Ann Oncol. 2011 Sep;22(9):2137-2143. doi: 10.1093/annonc/mdq734. Epub 2011 Feb 16. Ann Oncol. 2011. PMID: 21325451 Free article. Clinical Trial.

3

An integrin-targeted, pan-isoform, phosphoinositide-3 kinase inhibitor, SF1126, has activity against multiple myeloma in vivo.

De P, Dey N, Terakedis B, Bergsagel PL, Li ZH, Mahadevan D, Garlich JR, Trudel S, Makale MT, Durden DL. De P, et al. Among authors: mahadevan d. Cancer Chemother Pharmacol. 2013 Apr;71(4):867-81. doi: 10.1007/s00280-013-2078-0. Epub 2013 Jan 25. Cancer Chemother Pharmacol. 2013. PMID: 23355037 Free PMC article. Clinical Trial.

4

Phase I study of fixed dose gemcitabine plus epirubicin in patients with advanced solid malignancies.

Mahadevan D, Dreisbach L, Kristedja T, Williams D, Obregon Y, Kurtin S, Von Hoff DD. Mahadevan D, et al. Am J Clin Oncol. 2009 Dec;32(6):607-11. doi: 10.1097/COC.0b013e31819cc9ed. Am J Clin Oncol. 2009. PMID: 19593083 Clinical Trial.

5

Phase I trial of AEG35156 an antisense oligonucleotide to XIAP plus gemcitabine in patients with metastatic pancreatic ductal adenocarcinoma.

Mahadevan D, Chalasani P, Rensvold D, Kurtin S, Pretzinger C, Jolivet J, Ramanathan RK, Von Hoff DD, Weiss GJ. Mahadevan D, et al. Am J Clin Oncol. 2013 Jun;36(3):239-43. doi: 10.1097/COC.0b013e3182467a13. Am J Clin Oncol. 2013. PMID: 22441342 Clinical Trial.

6

Phase I trial of UNBS5162, a novel naphthalimide in patients with advanced solid tumors or lymphoma.

Mahadevan D, Northfelt DW, Chalasani P, Rensvold D, Kurtin S, Von Hoff DD, Borad MJ, Tibes R. Mahadevan D, et al. Int J Clin Oncol. 2013 Oct;18(5):934-41. doi: 10.1007/s10147-012-0475-8. Epub 2012 Oct 11. Int J Clin Oncol. 2013. PMID: 23053399 Free PMC article. Clinical Trial.

7

Tumor-stroma interactions in pancreatic ductal adenocarcinoma.

Mahadevan D, Von Hoff DD. Mahadevan D, et al. Mol Cancer Ther. 2007 Apr;6(4):1186-97. doi: 10.1158/1535-7163.MCT-06-0686. Epub 2007 Apr 3. Mol Cancer Ther. 2007. PMID: 17406031 Review.

8

AT9283, a novel aurora kinase inhibitor, suppresses tumor growth in aggressive B-cell lymphomas.

Qi W, Liu X, Cooke LS, Persky DO, Miller TP, Squires M, Mahadevan D. Qi W, et al. Among authors: mahadevan d. Int J Cancer. 2012 Jun 15;130(12):2997-3005. doi: 10.1002/ijc.26324. Epub 2011 Nov 19. Int J Cancer. 2012. PMID: 21796626

9

Design and activity of a murine and humanized anti-CEACAM6 single-chain variable fragment in the treatment of pancreatic cancer.

Riley CJ, Engelhardt KP, Saldanha JW, Qi W, Cooke LS, Zhu Y, Narayan ST, Shakalya K, Croce KD, Georgiev IG, Nagle RB, Garewal H, Von Hoff DD, Mahadevan D. Riley CJ, et al. Among authors: mahadevan d. Cancer Res. 2009 Mar 1;69(5):1933-40. doi: 10.1158/0008-5472.CAN-08-2707. Epub 2009 Feb 24. Cancer Res. 2009. PMID: 19244123 Free PMC article.

10

MP470, a novel receptor tyrosine kinase inhibitor, in combination with Erlotinib inhibits the HER family/PI3K/Akt pathway and tumor growth in prostate cancer.

Qi W, Cooke LS, Stejskal A, Riley C, Croce KD, Saldanha JW, Bearss D, Mahadevan D. Qi W, et al. Among authors: mahadevan d. BMC Cancer. 2009 May 11;9:142. doi: 10.1186/1471-2407-9-142. BMC Cancer. 2009. PMID: 19432987 Free PMC article.

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