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Epstein-Barr virus reactivation induces divergent abortive, reprogrammed, and host shutoff states by lytic progression.
SoRelle ED, Haynes LE, Willard KA, Chang B, Ch'ng J, Christofk H, Luftig MA. SoRelle ED, et al. Among authors: christofk h. bioRxiv [Preprint]. 2024 Jun 14:2024.06.14.598975. doi: 10.1101/2024.06.14.598975. bioRxiv. 2024. Update in: PLoS Pathog. 2024 Oct 24;20(10):e1012341. doi: 10.1371/journal.ppat.1012341 PMID: 38915538 Free PMC article. Updated. Preprint.
Fast metabolic response to drug intervention through analysis on a miniaturized, highly integrated molecular imaging system.
Wang J, Hwang K, Braas D, Dooraghi A, Nathanson D, Campbell DO, Gu Y, Sandberg T, Mischel P, Radu C, Chatziioannou AF, Phelps ME, Christofk H, Heath JR. Wang J, et al. Among authors: christofk h. J Nucl Med. 2013 Oct;54(10):1820-4. doi: 10.2967/jnumed.112.118497. Epub 2013 Aug 26. J Nucl Med. 2013. PMID: 23978446 Free PMC article.
The metabolite α-ketoglutarate extends lifespan by inhibiting ATP synthase and TOR.
Chin RM, Fu X, Pai MY, Vergnes L, Hwang H, Deng G, Diep S, Lomenick B, Meli VS, Monsalve GC, Hu E, Whelan SA, Wang JX, Jung G, Solis GM, Fazlollahi F, Kaweeteerawat C, Quach A, Nili M, Krall AS, Godwin HA, Chang HR, Faull KF, Guo F, Jiang M, Trauger SA, Saghatelian A, Braas D, Christofk HR, Clarke CF, Teitell MA, Petrascheck M, Reue K, Jung ME, Frand AR, Huang J. Chin RM, et al. Among authors: christofk hr. Nature. 2014 Jun 19;510(7505):397-401. doi: 10.1038/nature13264. Epub 2014 May 14. Nature. 2014. PMID: 24828042 Free PMC article.
2-Hydroxyglutarate Inhibits ATP Synthase and mTOR Signaling.
Fu X, Chin RM, Vergnes L, Hwang H, Deng G, Xing Y, Pai MY, Li S, Ta L, Fazlollahi F, Chen C, Prins RM, Teitell MA, Nathanson DA, Lai A, Faull KF, Jiang M, Clarke SG, Cloughesy TF, Graeber TG, Braas D, Christofk HR, Jung ME, Reue K, Huang J. Fu X, et al. Among authors: christofk hr. Cell Metab. 2015 Sep 1;22(3):508-15. doi: 10.1016/j.cmet.2015.06.009. Epub 2015 Jul 16. Cell Metab. 2015. PMID: 26190651 Free PMC article.
88 results