Orrú CD - Search Results

1

Real time quaking-induced conversion analysis of cerebrospinal fluid in sporadic Creutzfeldt-Jakob disease.

McGuire LI, Peden AH, Orrú CD, Wilham JM, Appleford NE, Mallinson G, Andrews M, Head MW, Caughey B, Will RG, Knight RS, Green AJ. McGuire LI, et al. Among authors: orru cd. Ann Neurol. 2012 Aug;72(2):278-85. doi: 10.1002/ana.23589. Ann Neurol. 2012. PMID: 22926858 Free PMC article.

2

Tau seeds occur before earliest Alzheimer's changes and are prevalent across neurodegenerative diseases.

Manca M, Standke HG, Browne DF, Huntley ML, Thomas OR, Orrú CD, Hughson AG, Kim Y, Zhang J, Tatsuoka C, Zhu X, Hiniker A, Coughlin DG, Galasko D, Kraus A. Manca M, et al. Among authors: orru cd. Acta Neuropathol. 2023 Jul;146(1):31-50. doi: 10.1007/s00401-023-02574-0. Epub 2023 May 8. Acta Neuropathol. 2023. PMID: 37154939 Free PMC article.

3

Altered energy metabolism in Fatal Familial Insomnia cerebral organoids is associated with astrogliosis and neuronal dysfunction.

Foliaki ST, Smith A, Schwarz B, Bohrnsen E, Bosio CM, Williams K, Orrú CD, Lachenauer H, Groveman BR, Haigh CL. Foliaki ST, et al. Among authors: orru cd. PLoS Genet. 2023 Jan 19;19(1):e1010565. doi: 10.1371/journal.pgen.1010565. eCollection 2023 Jan. PLoS Genet. 2023. PMID: 36656833 Free PMC article.

4

Human variant Creutzfeldt-Jakob disease and sheep scrapie PrP(res) detection using seeded conversion of recombinant prion protein.

Orrú CD, Wilham JM, Hughson AG, Raymond LD, McNally KL, Bossers A, Ligios C, Caughey B. Orrú CD, et al. Protein Eng Des Sel. 2009 Aug;22(8):515-21. doi: 10.1093/protein/gzp031. Epub 2009 Jul 1. Protein Eng Des Sel. 2009. PMID: 19570812 Free PMC article.

5

Rapid end-point quantitation of prion seeding activity with sensitivity comparable to bioassays.

Wilham JM, Orrú CD, Bessen RA, Atarashi R, Sano K, Race B, Meade-White KD, Taubner LM, Timmes A, Caughey B. Wilham JM, et al. Among authors: orru cd. PLoS Pathog. 2010 Dec 2;6(12):e1001217. doi: 10.1371/journal.ppat.1001217. PLoS Pathog. 2010. PMID: 21152012 Free PMC article.

6

Prion disease blood test using immunoprecipitation and improved quaking-induced conversion.

Orrú CD, Wilham JM, Raymond LD, Kuhn F, Schroeder B, Raeber AJ, Caughey B. Orrú CD, et al. mBio. 2011 May 10;2(3):e00078-11. doi: 10.1128/mBio.00078-11. Print 2011. mBio. 2011. PMID: 21558432 Free PMC article.

7

Prion seeded conversion and amplification assays.

Orrú CD, Caughey B. Orrú CD, et al. Top Curr Chem. 2011;305:121-33. doi: 10.1007/128_2011_184. Top Curr Chem. 2011. PMID: 21678135 Free PMC article. Review.

8

Sensitive and specific detection of sporadic Creutzfeldt-Jakob disease brain prion protein using real-time quaking-induced conversion.

Peden AH, McGuire LI, Appleford NEJ, Mallinson G, Wilham JM, Orrú CD, Caughey B, Ironside JW, Knight RS, Will RG, Green AJE, Head MW. Peden AH, et al. Among authors: orru cd. J Gen Virol. 2012 Feb;93(Pt 2):438-449. doi: 10.1099/vir.0.033365-0. Epub 2011 Oct 26. J Gen Virol. 2012. PMID: 22031526 Free PMC article.

9

Time course of prion seeding activity in cerebrospinal fluid of scrapie-infected hamsters after intratongue and intracerebral inoculations.

Orrù CD, Hughson AG, Race B, Raymond GJ, Caughey B. Orrù CD, et al. J Clin Microbiol. 2012 Apr;50(4):1464-6. doi: 10.1128/JCM.06099-11. Epub 2012 Jan 11. J Clin Microbiol. 2012. PMID: 22238438 Free PMC article.

10

New generation QuIC assays for prion seeding activity.

Orrù CD, Wilham JM, Vascellari S, Hughson AG, Caughey B. Orrù CD, et al. Prion. 2012 Apr-Jun;6(2):147-52. doi: 10.4161/pri.19430. Epub 2012 Apr 1. Prion. 2012. PMID: 22421206 Free PMC article. Review.

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