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ADCC develops over time during persistent infection with live-attenuated SIV and is associated with complete protection against SIV(mac)251 challenge.
Alpert MD, Harvey JD, Lauer WA, Reeves RK, Piatak M Jr, Carville A, Mansfield KG, Lifson JD, Li W, Desrosiers RC, Johnson RP, Evans DT. Alpert MD, et al. Among authors: desrosiers rc. PLoS Pathog. 2012;8(8):e1002890. doi: 10.1371/journal.ppat.1002890. Epub 2012 Aug 23. PLoS Pathog. 2012. PMID: 22927823 Free PMC article.
Immunization of macaques with single-cycle simian immunodeficiency virus (SIV) stimulates diverse virus-specific immune responses and reduces viral loads after challenge with SIVmac239.
Evans DT, Bricker JE, Sanford HB, Lang S, Carville A, Richardson BA, Piatak M Jr, Lifson JD, Mansfield KG, Desrosiers RC. Evans DT, et al. Among authors: desrosiers rc. J Virol. 2005 Jun;79(12):7707-20. doi: 10.1128/JVI.79.12.7707-7720.2005. J Virol. 2005. PMID: 15919923 Free PMC article.
SIV vpx is essential for macrophage infection but not for development of AIDS.
Westmoreland SV, Converse AP, Hrecka K, Hurley M, Knight H, Piatak M, Lifson J, Mansfield KG, Skowronski J, Desrosiers RC. Westmoreland SV, et al. Among authors: desrosiers rc. PLoS One. 2014 Jan 21;9(1):e84463. doi: 10.1371/journal.pone.0084463. eCollection 2014. PLoS One. 2014. PMID: 24465411 Free PMC article.
Persistent Low-Level Replication of SIVΔnef Drives Maturation of Antibody and CD8 T Cell Responses to Induce Protective Immunity against Vaginal SIV Infection.
Adnan S, Reeves RK, Gillis J, Wong FE, Yu Y, Camp JV, Li Q, Connole M, Li Y, Piatak M Jr, Lifson JD, Li W, Keele BF, Kozlowski PA, Desrosiers RC, Haase AT, Johnson RP. Adnan S, et al. Among authors: desrosiers rc. PLoS Pathog. 2016 Dec 13;12(12):e1006104. doi: 10.1371/journal.ppat.1006104. eCollection 2016 Dec. PLoS Pathog. 2016. PMID: 27959961 Free PMC article.
Vaccine protection against rectal acquisition of SIVmac239 in rhesus macaques.
Gonzalez-Nieto L, Castro IM, Bischof GF, Shin YC, Ricciardi MJ, Bailey VK, Dang CM, Pedreño-Lopez N, Magnani DM, Ejima K, Allison DB, Gil HM, Evans DT, Rakasz EG, Lifson JD, Desrosiers RC, Martins MA. Gonzalez-Nieto L, et al. Among authors: desrosiers rc. PLoS Pathog. 2019 Sep 30;15(9):e1008015. doi: 10.1371/journal.ppat.1008015. eCollection 2019 Sep. PLoS Pathog. 2019. PMID: 31568531 Free PMC article.
353 results