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Protein-protein-interaction network organization of the hypusine modification system.
Sievert H, Venz S, Platas-Barradas O, Dhople VM, Schaletzky M, Nagel CH, Braig M, Preukschas M, Pällmann N, Bokemeyer C, Brümmendorf TH, Pörtner R, Walther R, Duncan KE, Hauber J, Balabanov S. Sievert H, et al. Among authors: braig m. Mol Cell Proteomics. 2012 Nov;11(11):1289-305. doi: 10.1074/mcp.M112.019059. Epub 2012 Aug 10. Mol Cell Proteomics. 2012. PMID: 22888148 Free PMC article.
A novel mouse model for inhibition of DOHH-mediated hypusine modification reveals a crucial function in embryonic development, proliferation and oncogenic transformation.
Sievert H, Pällmann N, Miller KK, Hermans-Borgmeyer I, Venz S, Sendoel A, Preukschas M, Schweizer M, Boettcher S, Janiesch PC, Streichert T, Walther R, Hengartner MO, Manz MG, Brümmendorf TH, Bokemeyer C, Braig M, Hauber J, Duncan KE, Balabanov S. Sievert H, et al. Among authors: braig m. Dis Model Mech. 2014 Aug;7(8):963-76. doi: 10.1242/dmm.014449. Epub 2014 May 15. Dis Model Mech. 2014. PMID: 24832488 Free PMC article.
Biological Relevance and Therapeutic Potential of the Hypusine Modification System.
Pällmann N, Braig M, Sievert H, Preukschas M, Hermans-Borgmeyer I, Schweizer M, Nagel CH, Neumann M, Wild P, Haralambieva E, Hagel C, Bokemeyer C, Hauber J, Balabanov S. Pällmann N, et al. Among authors: braig m. J Biol Chem. 2015 Jul 24;290(30):18343-60. doi: 10.1074/jbc.M115.664490. Epub 2015 Jun 2. J Biol Chem. 2015. PMID: 26037925 Free PMC article.
Combination of a proteomics approach and reengineering of meso scale network models for prediction of mode-of-action for tyrosine kinase inhibitors.
Balabanov S, Wilhelm T, Venz S, Keller G, Scharf C, Pospisil H, Braig M, Barett C, Bokemeyer C, Walther R, Brümmendorf TH, Schuppert A. Balabanov S, et al. Among authors: braig m. PLoS One. 2013;8(1):e53668. doi: 10.1371/journal.pone.0053668. Epub 2013 Jan 9. PLoS One. 2013. PMID: 23326482 Free PMC article.
Abcg2 overexpression represents a novel mechanism for acquired resistance to the multi-kinase inhibitor Danusertib in BCR-ABL-positive cells in vitro.
Balabanov S, Gontarewicz A, Keller G, Raddrizzani L, Braig M, Bosotti R, Moll J, Jost E, Barett C, Rohe I, Bokemeyer C, Holyoake TL, Brümmendorf TH. Balabanov S, et al. Among authors: braig m. PLoS One. 2011 Apr 26;6(4):e19164. doi: 10.1371/journal.pone.0019164. PLoS One. 2011. PMID: 21541334 Free PMC article.
Ubiquitin carboxyl-terminal hydrolase 1 (UCHL1) is a potential tumour suppressor in prostate cancer and is frequently silenced by promoter methylation.
Ummanni R, Jost E, Braig M, Lohmann F, Mundt F, Barett C, Schlomm T, Sauter G, Senff T, Bokemeyer C, Sültmann H, Meyer-Schwesinger C, Brümmendorf TH, Balabanov S. Ummanni R, et al. Among authors: braig m. Mol Cancer. 2011 Oct 14;10:129. doi: 10.1186/1476-4598-10-129. Mol Cancer. 2011. PMID: 21999842 Free PMC article.
Evaluation of deoxyhypusine synthase inhibitors targeting BCR-ABL positive leukemias.
Ziegler P, Chahoud T, Wilhelm T, Pällman N, Braig M, Wiehle V, Ziegler S, Schröder M, Meier C, Kolodzik A, Rarey M, Panse J, Hauber J, Balabanov S, Brümmendorf TH. Ziegler P, et al. Among authors: braig m. Invest New Drugs. 2012 Dec;30(6):2274-83. doi: 10.1007/s10637-012-9810-1. Epub 2012 Mar 14. Invest New Drugs. 2012. PMID: 22415796
34 results