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106 results

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Page 1
Combined inhibition of Wee1 and Hsp90 activates intrinsic apoptosis in cancer cells.
Iwai A, Bourboulia D, Mollapour M, Jensen-Taubman S, Lee S, Donnelly AC, Yoshida S, Miyajima N, Tsutsumi S, Smith AK, Sun D, Wu X, Blagg BS, Trepel JB, Stetler-Stevenson WG, Neckers L. Iwai A, et al. Among authors: mollapour m. Cell Cycle. 2012 Oct 1;11(19):3649-55. doi: 10.4161/cc.21926. Epub 2012 Aug 30. Cell Cycle. 2012. PMID: 22935698 Free PMC article.
Visualizing the twists and turns of a molecular chaperone.
Neckers L, Tsutsumi S, Mollapour M. Neckers L, et al. Among authors: mollapour m. Nat Struct Mol Biol. 2009 Mar;16(3):235-6. doi: 10.1038/nsmb0309-235. Nat Struct Mol Biol. 2009. PMID: 19259122 No abstract available.
The complex dance of the molecular chaperone Hsp90.
Neckers L, Mollapour M, Tsutsumi S. Neckers L, et al. Among authors: mollapour m. Trends Biochem Sci. 2009 May;34(5):223-6. doi: 10.1016/j.tibs.2009.01.006. Epub 2009 Apr 7. Trends Biochem Sci. 2009. PMID: 19359180 Free PMC article.
Fumarate hydratase deficiency in renal cancer induces glycolytic addiction and hypoxia-inducible transcription factor 1alpha stabilization by glucose-dependent generation of reactive oxygen species.
Sudarshan S, Sourbier C, Kong HS, Block K, Valera Romero VA, Yang Y, Galindo C, Mollapour M, Scroggins B, Goode N, Lee MJ, Gourlay CW, Trepel J, Linehan WM, Neckers L. Sudarshan S, et al. Among authors: mollapour m. Mol Cell Biol. 2009 Aug;29(15):4080-90. doi: 10.1128/MCB.00483-09. Epub 2009 May 26. Mol Cell Biol. 2009. PMID: 19470762 Free PMC article.
Hsp90 charged-linker truncation reverses the functional consequences of weakened hydrophobic contacts in the N domain.
Tsutsumi S, Mollapour M, Graf C, Lee CT, Scroggins BT, Xu W, Haslerova L, Hessling M, Konstantinova AA, Trepel JB, Panaretou B, Buchner J, Mayer MP, Prodromou C, Neckers L. Tsutsumi S, et al. Among authors: mollapour m. Nat Struct Mol Biol. 2009 Nov;16(11):1141-7. doi: 10.1038/nsmb.1682. Epub 2009 Oct 18. Nat Struct Mol Biol. 2009. PMID: 19838189 Free PMC article.
Swe1Wee1-dependent tyrosine phosphorylation of Hsp90 regulates distinct facets of chaperone function.
Mollapour M, Tsutsumi S, Donnelly AC, Beebe K, Tokita MJ, Lee MJ, Lee S, Morra G, Bourboulia D, Scroggins BT, Colombo G, Blagg BS, Panaretou B, Stetler-Stevenson WG, Trepel JB, Piper PW, Prodromou C, Pearl LH, Neckers L. Mollapour M, et al. Mol Cell. 2010 Feb 12;37(3):333-43. doi: 10.1016/j.molcel.2010.01.005. Mol Cell. 2010. PMID: 20159553 Free PMC article.
Hsp90 phosphorylation, Wee1 and the cell cycle.
Mollapour M, Tsutsumi S, Neckers L. Mollapour M, et al. Cell Cycle. 2010 Jun 15;9(12):2310-6. doi: 10.4161/cc.9.12.12054. Epub 2010 Jun 15. Cell Cycle. 2010. PMID: 20519952 Free PMC article.
Targeting the dynamic HSP90 complex in cancer.
Trepel J, Mollapour M, Giaccone G, Neckers L. Trepel J, et al. Among authors: mollapour m. Nat Rev Cancer. 2010 Aug;10(8):537-49. doi: 10.1038/nrc2887. Nat Rev Cancer. 2010. PMID: 20651736 Free PMC article. Review.
106 results