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Page 1
Neuroprotection after stroke by targeting NOX4 as a source of oxidative stress.
Radermacher KA, Wingler K, Langhauser F, Altenhöfer S, Kleikers P, Hermans JJ, Hrabě de Angelis M, Kleinschnitz C, Schmidt HH. Radermacher KA, et al. Among authors: schmidt hh. Antioxid Redox Signal. 2013 Apr 20;18(12):1418-27. doi: 10.1089/ars.2012.4797. Epub 2012 Oct 16. Antioxid Redox Signal. 2013. PMID: 22937798 Free PMC article. Review.
The NOX toolbox: validating the role of NADPH oxidases in physiology and disease.
Altenhöfer S, Kleikers PW, Radermacher KA, Scheurer P, Rob Hermans JJ, Schiffers P, Ho H, Wingler K, Schmidt HH. Altenhöfer S, et al. Among authors: schmidt hh. Cell Mol Life Sci. 2012 Jul;69(14):2327-43. doi: 10.1007/s00018-012-1010-9. Epub 2012 May 31. Cell Mol Life Sci. 2012. PMID: 22648375 Free PMC article. Review.
NOX4 is an early initiator of neuropathic pain.
Geis C, Geuss E, Sommer C, Schmidt HH, Kleinschnitz C. Geis C, et al. Among authors: schmidt hh. Exp Neurol. 2017 Feb;288:94-103. doi: 10.1016/j.expneurol.2016.11.008. Epub 2016 Nov 14. Exp Neurol. 2017. PMID: 27856286
From single drug targets to synergistic network pharmacology in ischemic stroke.
Casas AI, Hassan AA, Larsen SJ, Gomez-Rangel V, Elbatreek M, Kleikers PWM, Guney E, Egea J, López MG, Baumbach J, Schmidt HHHW. Casas AI, et al. Proc Natl Acad Sci U S A. 2019 Apr 2;116(14):7129-7136. doi: 10.1073/pnas.1820799116. Epub 2019 Mar 20. Proc Natl Acad Sci U S A. 2019. PMID: 30894481 Free PMC article.
Post-stroke inhibition of induced NADPH oxidase type 4 prevents oxidative stress and neurodegeneration.
Kleinschnitz C, Grund H, Wingler K, Armitage ME, Jones E, Mittal M, Barit D, Schwarz T, Geis C, Kraft P, Barthel K, Schuhmann MK, Herrmann AM, Meuth SG, Stoll G, Meurer S, Schrewe A, Becker L, Gailus-Durner V, Fuchs H, Klopstock T, de Angelis MH, Jandeleit-Dahm K, Shah AM, Weissmann N, Schmidt HH. Kleinschnitz C, et al. Among authors: schmidt hh. PLoS Biol. 2010 Sep 21;8(9):e1000479. doi: 10.1371/journal.pbio.1000479. PLoS Biol. 2010. PMID: 20877715 Free PMC article.
524 results