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Factors affecting the pharmacokinetics and pharmacodynamics of PEGylated liposomal irinotecan (IHL-305) in patients with advanced solid tumors.
Wu H, Infante JR, Keedy VL, Jones SF, Chan E, Bendell JC, Lee W, Kirschbrown WP, Zamboni BA, Ikeda S, Kodaira H, Rothenberg ML, Burris HA 3rd, Zamboni WC. Wu H, et al. Among authors: kodaira h. Int J Nanomedicine. 2015 Feb 10;10:1201-9. doi: 10.2147/IJN.S62911. eCollection 2015. Int J Nanomedicine. 2015. PMID: 25709442 Free PMC article.
Quantitative evaluation of the impact of active efflux by p-glycoprotein and breast cancer resistance protein at the blood-brain barrier on the predictability of the unbound concentrations of drugs in the brain using cerebrospinal fluid concentration as a surrogate.
Kodaira H, Kusuhara H, Fujita T, Ushiki J, Fuse E, Sugiyama Y. Kodaira H, et al. J Pharmacol Exp Ther. 2011 Dec;339(3):935-44. doi: 10.1124/jpet.111.180398. Epub 2011 Sep 20. J Pharmacol Exp Ther. 2011. PMID: 21934030
The use of PVP as a polymeric carrier to improve the plasma half-life of drugs.
Kaneda Y, Tsutsumi Y, Yoshioka Y, Kamada H, Yamamoto Y, Kodaira H, Tsunoda S, Okamoto T, Mukai Y, Shibata H, Nakagawa S, Mayumi T. Kaneda Y, et al. Among authors: kodaira h. Biomaterials. 2004 Jul;25(16):3259-66. doi: 10.1016/j.biomaterials.2003.10.003. Biomaterials. 2004. PMID: 14980420
The targeting of anionized polyvinylpyrrolidone to the renal system.
Kodaira H, Tsutsumi Y, Yoshioka Y, Kamada H, Kaneda Y, Yamamoto Y, Tsunoda S, Okamoto T, Mukai Y, Shibata H, Nakagawa S, Mayumi T. Kodaira H, et al. Biomaterials. 2004 Aug;25(18):4309-15. doi: 10.1016/j.biomaterials.2003.10.097. Biomaterials. 2004. PMID: 15046921
91 results