Kulikauskas RM - Search Results

1

FAM123A binds to microtubules and inhibits the guanine nucleotide exchange factor ARHGEF2 to decrease actomyosin contractility.

Siesser PF, Motolese M, Walker MP, Goldfarb D, Gewain K, Yan F, Kulikauskas RM, Chien AJ, Wordeman L, Major MB. Siesser PF, et al. Among authors: kulikauskas rm. Sci Signal. 2012 Sep 4;5(240):ra64. doi: 10.1126/scisignal.2002871. Sci Signal. 2012. PMID: 22949735 Free PMC article.

2

WNT7B mediates autocrine Wnt/β-catenin signaling and anchorage-independent growth in pancreatic adenocarcinoma.

Arensman MD, Kovochich AN, Kulikauskas RM, Lay AR, Yang PT, Li X, Donahue T, Major MB, Moon RT, Chien AJ, Dawson DW. Arensman MD, et al. Among authors: kulikauskas rm. Oncogene. 2014 Feb 13;33(7):899-908. doi: 10.1038/onc.2013.23. Epub 2013 Feb 18. Oncogene. 2014. PMID: 23416978 Free PMC article.

3

Activated Wnt/beta-catenin signaling in melanoma is associated with decreased proliferation in patient tumors and a murine melanoma model.

Chien AJ, Moore EC, Lonsdorf AS, Kulikauskas RM, Rothberg BG, Berger AJ, Major MB, Hwang ST, Rimm DL, Moon RT. Chien AJ, et al. Among authors: kulikauskas rm. Proc Natl Acad Sci U S A. 2009 Jan 27;106(4):1193-8. doi: 10.1073/pnas.0811902106. Epub 2009 Jan 14. Proc Natl Acad Sci U S A. 2009. PMID: 19144919 Free PMC article.

4

Activation of Wnt/β-catenin signaling increases apoptosis in melanoma cells treated with trail.

Zimmerman ZF, Kulikauskas RM, Bomsztyk K, Moon RT, Chien AJ. Zimmerman ZF, et al. Among authors: kulikauskas rm. PLoS One. 2013 Jul 15;8(7):e69593. doi: 10.1371/journal.pone.0069593. Print 2013. PLoS One. 2013. PMID: 23869245 Free PMC article.

5

Regulating the response to targeted MEK inhibition in melanoma: enhancing apoptosis in NRAS- and BRAF-mutant melanoma cells with Wnt/β-catenin activation.

Conrad WH, Swift RD, Biechele TL, Kulikauskas RM, Moon RT, Chien AJ. Conrad WH, et al. Among authors: kulikauskas rm. Cell Cycle. 2012 Oct 15;11(20):3724-30. doi: 10.4161/cc.21645. Epub 2012 Aug 16. Cell Cycle. 2012. PMID: 22895053 Free PMC article.

6

Targeted BRAF inhibition impacts survival in melanoma patients with high levels of Wnt/β-catenin signaling.

Chien AJ, Haydu LE, Biechele TL, Kulikauskas RM, Rizos H, Kefford RF, Scolyer RA, Moon RT, Long GV. Chien AJ, et al. Among authors: kulikauskas rm. PLoS One. 2014 Apr 14;9(4):e94748. doi: 10.1371/journal.pone.0094748. eCollection 2014. PLoS One. 2014. PMID: 24733413 Free PMC article.

7

Wnt/β-catenin signaling and AXIN1 regulate apoptosis triggered by inhibition of the mutant kinase BRAFV600E in human melanoma.

Biechele TL, Kulikauskas RM, Toroni RA, Lucero OM, Swift RD, James RG, Robin NC, Dawson DW, Moon RT, Chien AJ. Biechele TL, et al. Among authors: kulikauskas rm. Sci Signal. 2012 Jan 10;5(206):ra3. doi: 10.1126/scisignal.2002274. Sci Signal. 2012. PMID: 22234612 Free PMC article.

8

WNT/β-catenin signaling regulates mitochondrial activity to alter the oncogenic potential of melanoma in a PTEN-dependent manner.

Brown K, Yang P, Salvador D, Kulikauskas R, Ruohola-Baker H, Robitaille AM, Chien AJ, Moon RT, Sherwood V. Brown K, et al. Oncogene. 2017 Jun 1;36(22):3119-3136. doi: 10.1038/onc.2016.450. Epub 2017 Jan 16. Oncogene. 2017. PMID: 28092677 Free PMC article.

9

Chemical-genetic screen identifies riluzole as an enhancer of Wnt/β-catenin signaling in melanoma.

Biechele TL, Camp ND, Fass DM, Kulikauskas RM, Robin NC, White BD, Taraska CM, Moore EC, Muster J, Karmacharya R, Haggarty SJ, Chien AJ, Moon RT. Biechele TL, et al. Among authors: kulikauskas rm. Chem Biol. 2010 Nov 24;17(11):1177-82. doi: 10.1016/j.chembiol.2010.08.012. Chem Biol. 2010. PMID: 21095567 Free PMC article.

10

Protein kinase PKN1 represses Wnt/β-catenin signaling in human melanoma cells.

James RG, Bosch KA, Kulikauskas RM, Yang PT, Robin NC, Toroni RA, Biechele TL, Berndt JD, von Haller PD, Eng JK, Wolf-Yadlin A, Chien AJ, Moon RT. James RG, et al. Among authors: kulikauskas rm. J Biol Chem. 2013 Nov 29;288(48):34658-70. doi: 10.1074/jbc.M113.500314. Epub 2013 Oct 10. J Biol Chem. 2013. PMID: 24114839 Free PMC article.

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