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Page 1
A novel partial agonist of peroxisome proliferator-activated receptor-gamma (PPARgamma) recruits PPARgamma-coactivator-1alpha, prevents triglyceride accumulation, and potentiates insulin signaling in vitro.
Burgermeister E, Schnoebelen A, Flament A, Benz J, Stihle M, Gsell B, Rufer A, Ruf A, Kuhn B, Märki HP, Mizrahi J, Sebokova E, Niesor E, Meyer M. Burgermeister E, et al. Among authors: mizrahi j. Mol Endocrinol. 2006 Apr;20(4):809-30. doi: 10.1210/me.2005-0171. Epub 2005 Dec 22. Mol Endocrinol. 2006. PMID: 16373399
Synthesis and biological evaluation of novel hexahydro-pyrido[3',2':4,5]pyrrolo[1,2-a]pyrazines as potent and selective 5-HT(2C) receptor agonists.
Richter HG, Adams DR, Benardeau A, Bickerdike MJ, Bentley JM, Blench TJ, Cliffe IA, Dourish C, Hebeisen P, Kennett GA, Knight AR, Malcolm CS, Mattei P, Misra A, Mizrahi J, Monck NJ, Plancher JM, Roever S, Roffey JR, Taylor S, Vickers SP. Richter HG, et al. Among authors: mizrahi j. Bioorg Med Chem Lett. 2006 Mar 1;16(5):1207-11. doi: 10.1016/j.bmcl.2005.11.083. Epub 2005 Dec 19. Bioorg Med Chem Lett. 2006. PMID: 16361098
Identification of 4-methyl-1,2,3,4,10,10a-hexahydropyrazino[1,2-a]indoles as 5-HT2C receptor agonists.
Röver S, Adams DR, Bénardeau A, Bentley JM, Bickerdike MJ, Bourson A, Cliffe IA, Coassolo P, Davidson JE, Dourish CT, Hebeisen P, Kennett GA, Knight AR, Malcolm CS, Mattei P, Misra A, Mizrahi J, Muller M, Porter RH, Richter H, Taylor S, Vickers SP. Röver S, et al. Among authors: mizrahi j. Bioorg Med Chem Lett. 2005 Aug 1;15(15):3604-8. doi: 10.1016/j.bmcl.2005.05.074. Bioorg Med Chem Lett. 2005. PMID: 15975787
Reduced plaque formation induced by rosiglitazone in an STZ-diabetes mouse model of atherosclerosis is associated with downregulation of adhesion molecules.
Tikellis C, Jandeleit-Dahm KA, Sheehy K, Murphy A, Chin-Dusting J, Kling D, Sebokova E, Cooper ME, Mizrahi J, Woollard KJ. Tikellis C, et al. Among authors: mizrahi j. Atherosclerosis. 2008 Jul;199(1):55-64. doi: 10.1016/j.atherosclerosis.2007.10.038. Epub 2008 Feb 21. Atherosclerosis. 2008. PMID: 18093596
PPARs and diabetes-associated atherosclerosis.
Calkin AC, Jandeleit-Dahm KA, Sebekova E, Allen TJ, Mizrahi J, Cooper ME, Tikellis C. Calkin AC, et al. Among authors: mizrahi j. Curr Pharm Des. 2007;13(26):2736-41. doi: 10.2174/138161207781662902. Curr Pharm Des. 2007. PMID: 17897018 Review.
203 results