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Respiratory toxicity of buprenorphine results from the blockage of P-glycoprotein-mediated efflux of norbuprenorphine at the blood-brain barrier in mice.
Alhaddad H, Cisternino S, Declèves X, Tournier N, Schlatter J, Chiadmi F, Risède P, Smirnova M, Besengez C, Scherrmann JM, Baud FJ, Mégarbane B. Alhaddad H, et al. Among authors: scherrmann jm. Crit Care Med. 2012 Dec;40(12):3215-23. doi: 10.1097/CCM.0b013e318265680a. Crit Care Med. 2012. PMID: 22975888
Impact of P-glycoprotein at the blood-brain barrier on the uptake of heroin and its main metabolites: behavioral effects and consequences on the transcriptional responses and reinforcing properties.
Seleman M, Chapy H, Cisternino S, Courtin C, Smirnova M, Schlatter J, Chiadmi F, Scherrmann JM, Noble F, Marie-Claire C. Seleman M, et al. Among authors: scherrmann jm. Psychopharmacology (Berl). 2014 Aug;231(16):3139-49. doi: 10.1007/s00213-014-3490-9. Epub 2014 Apr 5. Psychopharmacology (Berl). 2014. PMID: 24705903
298 results