Chirgadze DY - Search Results

1

Crystal structure of folliculin reveals a hidDENN function in genetically inherited renal cancer.

Nookala RK, Langemeyer L, Pacitto A, Ochoa-Montaño B, Donaldson JC, Blaszczyk BK, Chirgadze DY, Barr FA, Bazan JF, Blundell TL. Nookala RK, et al. Among authors: chirgadze dy. Open Biol. 2012 Aug;2(8):120071. doi: 10.1098/rsob.120071. Open Biol. 2012. PMID: 22977732 Free PMC article.

2

Domain structure of hepatocyte growth factor/scatter factor (HGF/SF).

Gherardi E, Hartmann G, Hepple J, Chirgadze D, Srinivasan N, Blundell T. Gherardi E, et al. Ciba Found Symp. 1997;212:84-93; discussion 93-104. doi: 10.1002/9780470515457.ch6. Ciba Found Symp. 1997. PMID: 9524765 Review.

3

Insights into the structure of hepatocyte growth factor/scatter factor (HGF/SF) and implications for receptor activation.

Chirgadze DY, Hepple J, Byrd RA, Sowdhamini R, Blundell TL, Gherardi E. Chirgadze DY, et al. FEBS Lett. 1998 Jun 23;430(1-2):126-9. doi: 10.1016/s0014-5793(98)00558-4. FEBS Lett. 1998. PMID: 9678607 Free article. Review.

4

Crystal structure of the NK1 fragment of HGF/SF suggests a novel mode for growth factor dimerization and receptor binding.

Chirgadze DY, Hepple JP, Zhou H, Byrd RA, Blundell TL, Gherardi E. Chirgadze DY, et al. Nat Struct Biol. 1999 Jan;6(1):72-9. doi: 10.1038/4947. Nat Struct Biol. 1999. PMID: 9886295

5

Protein-protein interactions in receptor activation and intracellular signalling.

Blundell TL, Burke DF, Chirgadze D, Dhanaraj V, Hyvönen M, Innis CA, Parisini E, Pellegrini L, Sayed M, Sibanda BL. Blundell TL, et al. Biol Chem. 2000 Sep-Oct;381(9-10):955-9. doi: 10.1515/BC.2000.117. Biol Chem. 2000. PMID: 11076027 Review.

6

Crystal structures of NK1-heparin complexes reveal the basis for NK1 activity and enable engineering of potent agonists of the MET receptor.

Lietha D, Chirgadze DY, Mulloy B, Blundell TL, Gherardi E. Lietha D, et al. Among authors: chirgadze dy. EMBO J. 2001 Oct 15;20(20):5543-55. doi: 10.1093/emboj/20.20.5543. EMBO J. 2001. PMID: 11597998 Free PMC article.

7

A new crystal form of the NK1 splice variant of HGF/SF demonstrates extensive hinge movement and suggests that the NK1 dimer originates by domain swapping.

Watanabe K, Chirgadze DY, Lietha D, de Jonge H, Blundell TL, Gherardi E. Watanabe K, et al. Among authors: chirgadze dy. J Mol Biol. 2002 May 31;319(2):283-8. doi: 10.1016/S0022-2836(02)00199-7. J Mol Biol. 2002. PMID: 12051906

8

Molecular dissection of the interaction between the small G proteins Rac1 and RhoA and protein kinase C-related kinase 1 (PRK1).

Owen D, Lowe PN, Nietlispach D, Brosnan CE, Chirgadze DY, Parker PJ, Blundell TL, Mott HR. Owen D, et al. Among authors: chirgadze dy. J Biol Chem. 2003 Dec 12;278(50):50578-87. doi: 10.1074/jbc.M304313200. Epub 2003 Sep 26. J Biol Chem. 2003. PMID: 14514689 Free article.

9

Structural constraints on protein self-processing in L-aspartate-alpha-decarboxylase.

Schmitzberger F, Kilkenny ML, Lobley CM, Webb ME, Vinkovic M, Matak-Vinkovic D, Witty M, Chirgadze DY, Smith AG, Abell C, Blundell TL. Schmitzberger F, et al. Among authors: chirgadze dy. EMBO J. 2003 Dec 1;22(23):6193-204. doi: 10.1093/emboj/cdg575. EMBO J. 2003. PMID: 14633979 Free PMC article.

10

High-resolution crystal structure of the human Notch 1 ankyrin domain.

Ehebauer MT, Chirgadze DY, Hayward P, Martinez Arias A, Blundell TL. Ehebauer MT, et al. Among authors: chirgadze dy. Biochem J. 2005 Nov 15;392(Pt 1):13-20. doi: 10.1042/BJ20050515. Biochem J. 2005. PMID: 16011479 Free PMC article.

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