Li Q - Search Results

1

Guaianolide sesquiterpene lactones, a source to discover agents that selectively inhibit acute myelogenous leukemia stem and progenitor cells.

Zhang Q, Lu Y, Ding Y, Zhai J, Ji Q, Ma W, Yang M, Fan H, Long J, Tong Z, Shi Y, Jia Y, Han B, Zhang W, Qiu C, Ma X, Li Q, Shi Q, Zhang H, Li D, Zhang J, Lin J, Li LY, Gao Y, Chen Y. Zhang Q, et al. Among authors: li ly, li d, li q. J Med Chem. 2012 Oct 25;55(20):8757-69. doi: 10.1021/jm301064b. Epub 2012 Oct 11. J Med Chem. 2012. PMID: 22985027

2

Syntheses and Biological Evaluation of Costunolide, Parthenolide, and Their Fluorinated Analogues.

Yang ZJ, Ge WZ, Li QY, Lu Y, Gong JM, Kuang BJ, Xi X, Wu H, Zhang Q, Chen Y. Yang ZJ, et al. Among authors: li qy. J Med Chem. 2015 Sep 10;58(17):7007-20. doi: 10.1021/acs.jmedchem.5b00915. Epub 2015 Aug 20. J Med Chem. 2015. PMID: 26226279

3

Natural Product Micheliolide (MCL) Irreversibly Activates Pyruvate Kinase M2 and Suppresses Leukemia.

Li J, Li S, Guo J, Li Q, Long J, Ma C, Ding Y, Yan C, Li L, Wu Z, Zhu H, Li KK, Wen L, Zhang Q, Xue Q, Zhao C, Liu N, Ivanov I, Luo M, Xi R, Long H, Wang PG, Chen Y. Li J, et al. Among authors: li kk, li s, li l, li q. J Med Chem. 2018 May 10;61(9):4155-4164. doi: 10.1021/acs.jmedchem.8b00241. Epub 2018 Apr 29. J Med Chem. 2018. PMID: 29641204 Free PMC article.

4

Synthesis and biological evaluation of nannocystin analogues toward understanding the binding role of the (2R,3S)-Epoxide in nannocystin A.

Tian Y, Xu X, Ding Y, Hao X, Bai Y, Tang Y, Zhang X, Li Q, Yang Z, Zhang W, Chen Y. Tian Y, et al. Among authors: li q. Eur J Med Chem. 2018 Apr 25;150:626-632. doi: 10.1016/j.ejmech.2018.03.012. Epub 2018 Mar 20. Eur J Med Chem. 2018. PMID: 29554614

5

ACT001 can prevent and reverse tamoxifen resistance in human breast cancer cell lines by inhibiting NF-κB activation.

Jin XH, Jia YS, Shi YH, Li QY, Bao SQ, Lu WP, Tong ZS. Jin XH, et al. J Cell Biochem. 2019 Feb;120(2):1386-1397. doi: 10.1002/jcb.27146. Epub 2018 Nov 18. J Cell Biochem. 2019. PMID: 30450651

6

ACT001 modulates the NF-κB/MnSOD/ROS axis by targeting IKKβ to inhibit glioblastoma cell growth.

Li Q, Sun Y, Liu B, Li J, Hao X, Ge W, Zhang X, Bao S, Gong J, Jiang Z, Qiu C, Zhao L, Zhao Y, Chen Y, Yang X, Ding Y, Wu Z. Li Q, et al. Among authors: li j. J Mol Med (Berl). 2020 Feb;98(2):263-277. doi: 10.1007/s00109-019-01839-0. Epub 2020 Jan 4. J Mol Med (Berl). 2020. PMID: 31901951

7

Chemical modification of ovatodiolide revealed a promising amino-prodrug with improved pharmacokinetic profile.

Xiang J , Zhang X , Wang D , Li J , Li Q , Wang Q , Ding Y , Chen T , Sun Y , Bao S , Chen J , Li D , Wang L , Chen Y . Xiang J , et al. Among authors: li d, li j, li q. Chem Commun (Camb). 2020 Sep 25;56(75):11018-11021. doi: 10.1039/c9cc07573a. Epub 2020 Aug 28. Chem Commun (Camb). 2020. PMID: 32856652

8

Design, Synthesis and Biological Evaluation of Jahanyne Analogs as Cell Cycle Arrest Inducers.

Ye B, Gong J, Li Q, Bao S, Zhang X, Chen J, Meng Q, Chen B, Jiang P, Wang L, Chen Y. Ye B, et al. Among authors: li q. Mar Drugs. 2020 Mar 23;18(3):176. doi: 10.3390/md18030176. Mar Drugs. 2020. PMID: 32210159 Free PMC article.

9

Dimethylaminomicheliolide (DMAMCL) Suppresses the Proliferation of Glioblastoma Cells via Targeting Pyruvate Kinase 2 (PKM2) and Rewiring Aerobic Glycolysis.

Guo J, Xue Q, Liu K, Ge W, Liu W, Wang J, Zhang M, Li QY, Cai D, Shan C, Zhang C, Liu X, Li J. Guo J, et al. Among authors: li j, li qy. Front Oncol. 2019 Oct 2;9:993. doi: 10.3389/fonc.2019.00993. eCollection 2019. Front Oncol. 2019. PMID: 31632919 Free PMC article.

10

ACT001 reduces the expression of PD-L1 by inhibiting the phosphorylation of STAT3 in glioblastoma.

Tong L, Li J, Li Q, Wang X, Medikonda R, Zhao T, Li T, Ma H, Yi L, Liu P, Xie Y, Choi J, Yu S, Lin Y, Dong J, Huang Q, Jin X, Lim M, Yang X. Tong L, et al. Among authors: li t, li j, li q. Theranostics. 2020 May 1;10(13):5943-5956. doi: 10.7150/thno.41498. eCollection 2020. Theranostics. 2020. PMID: 32483429 Free PMC article.

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