Cheng K - Search Results

1

Selection, synthesis, and anti-inflammatory evaluation of the arylidene malonate derivatives as TLR4 signaling inhibitors.

Zhang S, Cheng K, Wang X, Yin H. Zhang S, et al. Among authors: cheng k. Bioorg Med Chem. 2012 Oct 15;20(20):6073-9. doi: 10.1016/j.bmc.2012.08.022. Epub 2012 Aug 25. Bioorg Med Chem. 2012. PMID: 22985959 Free PMC article.

2

Synthesis, biological evaluation and molecular docking studies of amide-coupled benzoic nitrogen mustard derivatives as potential antitumor agents.

Zheng QZ, Zhang F, Cheng K, Yang Y, Chen Y, Qian Y, Zhang HJ, Li HQ, Zhou CF, An SQ, Jiao QC, Zhu HL. Zheng QZ, et al. Among authors: cheng k. Bioorg Med Chem. 2010 Jan 15;18(2):880-6. doi: 10.1016/j.bmc.2009.11.037. Epub 2009 Nov 22. Bioorg Med Chem. 2010. PMID: 20005116

3

Synthesis, biological evaluation, and molecular docking studies of 2-chloropyridine derivatives possessing 1,3,4-oxadiazole moiety as potential antitumor agents.

Zheng QZ, Zhang XM, Xu Y, Cheng K, Jiao QC, Zhu HL. Zheng QZ, et al. Among authors: cheng k. Bioorg Med Chem. 2010 Nov 15;18(22):7836-41. doi: 10.1016/j.bmc.2010.09.051. Epub 2010 Sep 25. Bioorg Med Chem. 2010. PMID: 20947362

4

Small-molecule inhibitors of the TLR3/dsRNA complex.

Cheng K, Wang X, Yin H. Cheng K, et al. J Am Chem Soc. 2011 Mar 23;133(11):3764-7. doi: 10.1021/ja111312h. Epub 2011 Feb 28. J Am Chem Soc. 2011. PMID: 21355588 Free PMC article.

5

Development of β-amino alcohol derivatives that inhibit Toll-like receptor 4 mediated inflammatory response as potential antiseptics.

Chavez SA, Martinko AJ, Lau C, Pham MN, Cheng K, Bevan DE, Mollnes TE, Yin H. Chavez SA, et al. Among authors: cheng k. J Med Chem. 2011 Jul 14;54(13):4659-69. doi: 10.1021/jm2003365. Epub 2011 Jun 2. J Med Chem. 2011. PMID: 21591694 Free PMC article.

6

Morphine activates neuroinflammation in a manner parallel to endotoxin.

Wang X, Loram LC, Ramos K, de Jesus AJ, Thomas J, Cheng K, Reddy A, Somogyi AA, Hutchinson MR, Watkins LR, Yin H. Wang X, et al. Among authors: cheng k. Proc Natl Acad Sci U S A. 2012 Apr 17;109(16):6325-30. doi: 10.1073/pnas.1200130109. Epub 2012 Apr 2. Proc Natl Acad Sci U S A. 2012. PMID: 22474354 Free PMC article.

7

Toll-like receptor (TLR) 3 as a surrogate sensor of retroviral infection in human cells.

Miyauchi K, Urano E, Takeda S, Murakami T, Okada Y, Cheng K, Yin H, Kubo M, Komano J. Miyauchi K, et al. Among authors: cheng k. Biochem Biophys Res Commun. 2012 Aug 3;424(3):519-23. doi: 10.1016/j.bbrc.2012.06.148. Epub 2012 Jul 4. Biochem Biophys Res Commun. 2012. PMID: 22771581

8

Discovery of small-molecule inhibitors of the TLR1/TLR2 complex.

Cheng K, Wang X, Zhang S, Yin H. Cheng K, et al. Angew Chem Int Ed Engl. 2012 Dec 3;51(49):12246-9. doi: 10.1002/anie.201204910. Epub 2012 Sep 11. Angew Chem Int Ed Engl. 2012. PMID: 22969053 Free PMC article.

9

Rifampin inhibits Toll-like receptor 4 signaling by targeting myeloid differentiation protein 2 and attenuates neuropathic pain.

Wang X, Grace PM, Pham MN, Cheng K, Strand KA, Smith C, Li J, Watkins LR, Yin H. Wang X, et al. Among authors: cheng k. FASEB J. 2013 Jul;27(7):2713-22. doi: 10.1096/fj.12-222992. Epub 2013 Apr 8. FASEB J. 2013. PMID: 23568774 Free PMC article.

10

Design, synthesis and antibacterial activity studies of thiazole derivatives as potent ecKAS III inhibitors.

Cheng K, Xue JY, Zhu HL. Cheng K, et al. Bioorg Med Chem Lett. 2013 Jul 15;23(14):4235-8. doi: 10.1016/j.bmcl.2013.05.006. Epub 2013 May 10. Bioorg Med Chem Lett. 2013. PMID: 23731945

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