Xie Y - Search Results

1

Purinergic receptor antagonist A438079 protects against acetaminophen-induced liver injury by inhibiting p450 isoenzymes, not by inflammasome activation.

Xie Y, Williams CD, McGill MR, Lebofsky M, Ramachandran A, Jaeschke H. Xie Y, et al. Toxicol Sci. 2013 Jan;131(1):325-35. doi: 10.1093/toxsci/kfs283. Epub 2012 Sep 17. Toxicol Sci. 2013. PMID: 22986947 Free PMC article.

2

Acetaminophen-induced liver injury in rats and mice: comparison of protein adducts, mitochondrial dysfunction, and oxidative stress in the mechanism of toxicity.

McGill MR, Williams CD, Xie Y, Ramachandran A, Jaeschke H. McGill MR, et al. Among authors: xie y. Toxicol Appl Pharmacol. 2012 Nov 1;264(3):387-94. doi: 10.1016/j.taap.2012.08.015. Epub 2012 Aug 23. Toxicol Appl Pharmacol. 2012. PMID: 22980195 Free PMC article.

3

Models of drug-induced liver injury for evaluation of phytotherapeutics and other natural products.

Jaeschke H, Williams CD, McGill MR, Xie Y, Ramachandran A. Jaeschke H, et al. Among authors: xie y. Food Chem Toxicol. 2013 May;55:279-89. doi: 10.1016/j.fct.2012.12.063. Epub 2013 Jan 22. Food Chem Toxicol. 2013. PMID: 23353004 Free PMC article. Review.

4

Plasma and liver acetaminophen-protein adduct levels in mice after acetaminophen treatment: dose-response, mechanisms, and clinical implications.

McGill MR, Lebofsky M, Norris HR, Slawson MH, Bajt ML, Xie Y, Williams CD, Wilkins DG, Rollins DE, Jaeschke H. McGill MR, et al. Among authors: xie y. Toxicol Appl Pharmacol. 2013 Jun 15;269(3):240-9. doi: 10.1016/j.taap.2013.03.026. Epub 2013 Apr 6. Toxicol Appl Pharmacol. 2013. PMID: 23571099 Free PMC article.

5

Receptor interacting protein kinase 3 is a critical early mediator of acetaminophen-induced hepatocyte necrosis in mice.

Ramachandran A, McGill MR, Xie Y, Ni HM, Ding WX, Jaeschke H. Ramachandran A, et al. Among authors: xie y. Hepatology. 2013 Dec;58(6):2099-108. doi: 10.1002/hep.26547. Epub 2013 Oct 11. Hepatology. 2013. PMID: 23744808 Free PMC article.

6

The gap junction inhibitor 2-aminoethoxy-diphenyl-borate protects against acetaminophen hepatotoxicity by inhibiting cytochrome P450 enzymes and c-jun N-terminal kinase activation.

Du K, Williams CD, McGill MR, Xie Y, Farhood A, Vinken M, Jaeschke H. Du K, et al. Among authors: xie y. Toxicol Appl Pharmacol. 2013 Dec 15;273(3):484-91. doi: 10.1016/j.taap.2013.09.010. Epub 2013 Sep 23. Toxicol Appl Pharmacol. 2013. PMID: 24070586 Free PMC article.

7

Mechanisms of acetaminophen-induced cell death in primary human hepatocytes.

Xie Y, McGill MR, Dorko K, Kumer SC, Schmitt TM, Forster J, Jaeschke H. Xie Y, et al. Toxicol Appl Pharmacol. 2014 Sep 15;279(3):266-274. doi: 10.1016/j.taap.2014.05.010. Epub 2014 Jun 3. Toxicol Appl Pharmacol. 2014. PMID: 24905542 Free PMC article.

8

The role of the c-Jun N-terminal kinases 1/2 and receptor-interacting protein kinase 3 in furosemide-induced liver injury.

McGill MR, Du K, Xie Y, Bajt ML, Ding WX, Jaeschke H. McGill MR, et al. Among authors: xie y. Xenobiotica. 2015 May;45(5):442-9. doi: 10.3109/00498254.2014.986250. Epub 2014 Nov 25. Xenobiotica. 2015. PMID: 25423287 Free PMC article.

9

Inhibitor of apoptosis signal-regulating kinase 1 protects against acetaminophen-induced liver injury.

Xie Y, Ramachandran A, Breckenridge DG, Liles JT, Lebofsky M, Farhood A, Jaeschke H. Xie Y, et al. Toxicol Appl Pharmacol. 2015 Jul 1;286(1):1-9. doi: 10.1016/j.taap.2015.03.019. Epub 2015 Mar 25. Toxicol Appl Pharmacol. 2015. PMID: 25818599 Free PMC article.

10

Resveratrol prevents protein nitration and release of endonucleases from mitochondria during acetaminophen hepatotoxicity.

Du K, McGill MR, Xie Y, Bajt ML, Jaeschke H. Du K, et al. Among authors: xie y. Food Chem Toxicol. 2015 Jul;81:62-70. doi: 10.1016/j.fct.2015.04.014. Epub 2015 Apr 9. Food Chem Toxicol. 2015. PMID: 25865938 Free PMC article.

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