Purohit MK - Search Results

1

Novel cytidine-based orotidine-5'-monophosphate decarboxylase inhibitors with an unusual twist.

Purohit MK, Poduch E, Wei LW, Crandall IE, To T, Kain KC, Pai EF, Kotra LP. Purohit MK, et al. J Med Chem. 2012 Nov 26;55(22):9988-97. doi: 10.1021/jm301176r. Epub 2012 Oct 18. J Med Chem. 2012. PMID: 22991951

2

Disulfide linked pyrazole derivatives inhibit phagocytosis of opsonized blood cells.

Purohit MK, Scovell I, Neschadim A, Katsman Y, Branch DR, Kotra LP. Purohit MK, et al. Bioorg Med Chem Lett. 2013 Apr 15;23(8):2324-7. doi: 10.1016/j.bmcl.2013.02.064. Epub 2013 Feb 26. Bioorg Med Chem Lett. 2013. PMID: 23489619

3

Small molecule mimetics of an interferon-α receptor interacting domain.

Bello AM, Wei L, Majchrzak-Kita B, Salum N, Purohit MK, Fish EN, Kotra LP. Bello AM, et al. Among authors: purohit mk. Bioorg Med Chem. 2014 Feb 1;22(3):978-85. doi: 10.1016/j.bmc.2013.12.049. Epub 2014 Jan 2. Bioorg Med Chem. 2014. PMID: 24433965

4

Structure-activity relationships of pyrazole derivatives as potential therapeutics for immune thrombocytopenias.

Purohit MK, Chakka SK, Scovell I, Neschadim A, Bello AM, Salum N, Katsman Y, Bareau MC, Branch DR, Kotra LP. Purohit MK, et al. Bioorg Med Chem. 2014 May 1;22(9):2739-52. doi: 10.1016/j.bmc.2014.03.016. Epub 2014 Mar 19. Bioorg Med Chem. 2014. PMID: 24685704

5

Immunological targets in inflammation from the small molecule perspective.

Bello AM, Purohit MK, Cui TJ, Stead SB, Kotra LP. Bello AM, et al. Among authors: purohit mk. Antiinflamm Antiallergy Agents Med Chem. 2011;10(2):121-31. doi: 10.2174/1871523011107020121. Antiinflamm Antiallergy Agents Med Chem. 2011. PMID: 25182059

6

Guaifenesin derivatives promote neurite outgrowth and protect diabetic mice from neuropathy.

Hadimani MB, Purohit MK, Vanampally C, Van der Ploeg R, Arballo V, Morrow D, Frizzi KE, Calcutt NA, Fernyhough P, Kotra LP. Hadimani MB, et al. Among authors: purohit mk. J Med Chem. 2013 Jun 27;56(12):5071-8. doi: 10.1021/jm400401y. Epub 2013 Jun 13. J Med Chem. 2013. PMID: 23758573

7

Milk derived extracellular vesicle uptake in human microglia regulates the DNA methylation machinery : Short title: milk-derived extracellular vesicles and the epigenetic machinery.

Wijenayake S, Eisha S, Purohit MK, McGowan PO. Wijenayake S, et al. Among authors: purohit mk. Sci Rep. 2024 Nov 19;14(1):28630. doi: 10.1038/s41598-024-79724-1. Sci Rep. 2024. PMID: 39562680 Free PMC article.

8

Comparative analysis of the catalysis and stability of the native, recombinant and metagenomic alkaline proteases in organic solvents.

Purohit MK, Rathore DS, Koladiya G, Pandey S, Singh SP. Purohit MK, et al. Environ Sci Pollut Res Int. 2022 Nov;29(53):80968-80982. doi: 10.1007/s11356-022-21411-7. Epub 2022 Jun 21. Environ Sci Pollut Res Int. 2022. PMID: 35725880

9

A metagenomic alkaline protease from saline habitat: cloning, over-expression and functional attributes.

Purohit MK, Singh SP. Purohit MK, et al. Int J Biol Macromol. 2013 Feb;53:138-43. doi: 10.1016/j.ijbiomac.2012.10.032. Epub 2012 Nov 23. Int J Biol Macromol. 2013. PMID: 23178370

10

Air1 zinc knuckles 4 and 5 and a conserved IWRXY motif are critical for the function and integrity of the Trf4/5-Air1/2-Mtr4 polyadenylation (TRAMP) RNA quality control complex.

Fasken MB, Leung SW, Banerjee A, Kodani MO, Chavez R, Bowman EA, Purohit MK, Rubinson ME, Rubinson EH, Corbett AH. Fasken MB, et al. Among authors: purohit mk. J Biol Chem. 2011 Oct 28;286(43):37429-45. doi: 10.1074/jbc.M111.271494. Epub 2011 Aug 30. J Biol Chem. 2011. PMID: 21878619 Free PMC article.

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