O'Reilly S - Search Results

1

Inhibition of RelA-Ser536 phosphorylation by a competing peptide reduces mouse liver fibrosis without blocking the innate immune response.

Moles A, Sanchez AM, Banks PS, Murphy LB, Luli S, Borthwick L, Fisher A, O'Reilly S, van Laar JM, White SA, Perkins ND, Burt AD, Mann DA, Oakley F. Moles A, et al. Hepatology. 2013 Feb;57(2):817-28. doi: 10.1002/hep.26068. Epub 2013 Jan 8. Hepatology. 2013. PMID: 22996371 Free PMC article.

2

The c-Rel subunit of NF-κB regulates epidermal homeostasis and promotes skin fibrosis in mice.

Fullard N, Moles A, O'Reilly S, van Laar JM, Faini D, Diboll J, Reynolds NJ, Mann DA, Reichelt J, Oakley F. Fullard N, et al. Am J Pathol. 2013 Jun;182(6):2109-20. doi: 10.1016/j.ajpath.2013.02.016. Epub 2013 Apr 4. Am J Pathol. 2013. PMID: 23562440 Free PMC article.

3

T cells in systemic sclerosis: a reappraisal.

O'Reilly S, Hügle T, van Laar JM. O'Reilly S, et al. Rheumatology (Oxford). 2012 Sep;51(9):1540-9. doi: 10.1093/rheumatology/kes090. Epub 2012 May 9. Rheumatology (Oxford). 2012. PMID: 22577083 Review.

4

Serum amyloid A induces interleukin-6 in dermal fibroblasts via Toll-like receptor 2, interleukin-1 receptor-associated kinase 4 and nuclear factor-κB.

O'Reilly S, Cant R, Ciechomska M, Finnigan J, Oakley F, Hambleton S, van Laar JM. O'Reilly S, et al. Immunology. 2014 Nov;143(3):331-40. doi: 10.1111/imm.12260. Immunology. 2014. PMID: 24476318 Free PMC article.

5

Targeting the TLR4-MD2 axis in systemic sclerosis.

O'Reilly S, van Laar JM. O'Reilly S, et al. Nat Rev Rheumatol. 2018 Oct;14(10):564-566. doi: 10.1038/s41584-018-0077-6. Nat Rev Rheumatol. 2018. PMID: 30181583 No abstract available.

6

cRel expression regulates distinct transcriptional and functional profiles driving fibroblast matrix production in systemic sclerosis.

Worrell JC, Leslie J, Smith GR, Zaki MYW, Paish HL, Knox A, James ML, Cartwright TN, O'Reilly S, Kania G, Distler O, Distler JHW, Herrick AL, Jeziorska M, Borthwick LA, Fisher AJ, Mann J, Mann DA, Oakley F. Worrell JC, et al. Rheumatology (Oxford). 2020 Dec 1;59(12):3939-3951. doi: 10.1093/rheumatology/keaa272. Rheumatology (Oxford). 2020. PMID: 32725139 Free article.

7

MiR-29a reduces TIMP-1 production by dermal fibroblasts via targeting TGF-β activated kinase 1 binding protein 1, implications for systemic sclerosis.

Ciechomska M, O'Reilly S, Suwara M, Bogunia-Kubik K, van Laar JM. Ciechomska M, et al. PLoS One. 2014 Dec 30;9(12):e115596. doi: 10.1371/journal.pone.0115596. eCollection 2014. PLoS One. 2014. PMID: 25549087 Free PMC article. Clinical Trial.

8

Interleukin-6 (IL-6) trans signaling drives a STAT3-dependent pathway that leads to hyperactive transforming growth factor-β (TGF-β) signaling promoting SMAD3 activation and fibrosis via Gremlin protein.

O'Reilly S, Ciechomska M, Cant R, van Laar JM. O'Reilly S, et al. J Biol Chem. 2014 Apr 4;289(14):9952-60. doi: 10.1074/jbc.M113.545822. Epub 2014 Feb 18. J Biol Chem. 2014. PMID: 24550394 Free PMC article. Clinical Trial.

9

Differentiation potential of CD14+ monocytes into myofibroblasts in patients with systemic sclerosis.

Binai N, O'Reilly S, Griffiths B, van Laar JM, Hügle T. Binai N, et al. PLoS One. 2012;7(3):e33508. doi: 10.1371/journal.pone.0033508. Epub 2012 Mar 14. PLoS One. 2012. PMID: 22432031 Free PMC article.

10

Role of toll-like receptors in systemic sclerosis.

Ciechomska M, Cant R, Finnigan J, van Laar JM, O'Reilly S. Ciechomska M, et al. Expert Rev Mol Med. 2013 Aug 28;15:e9. doi: 10.1017/erm.2013.10. Expert Rev Mol Med. 2013. PMID: 23985302 Review.

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