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194 results

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γ-Secretase inhibitor I induces apoptosis in chronic lymphocytic leukemia cells by proteasome inhibition, endoplasmic reticulum stress increase and notch down-regulation.
Rosati E, Sabatini R, De Falco F, Del Papa B, Falzetti F, Di Ianni M, Cavalli L, Fettucciari K, Bartoli A, Screpanti I, Marconi P. Rosati E, et al. Among authors: de falco f. Int J Cancer. 2013 Apr 15;132(8):1940-53. doi: 10.1002/ijc.27863. Epub 2012 Oct 17. Int J Cancer. 2013. PMID: 23001755
Novel targets for endoplasmic reticulum stress-induced apoptosis in B-CLL.
Rosati E, Sabatini R, Rampino G, De Falco F, Di Ianni M, Falzetti F, Fettucciari K, Bartoli A, Screpanti I, Marconi P. Rosati E, et al. Among authors: de falco f. Blood. 2010 Oct 14;116(15):2713-23. doi: 10.1182/blood-2010-03-275628. Epub 2010 Jul 13. Blood. 2010. PMID: 20628148 Free article.
Bepridil exhibits anti-leukemic activity associated with NOTCH1 pathway inhibition in chronic lymphocytic leukemia.
Baldoni S, Del Papa B, Dorillo E, Aureli P, De Falco F, Rompietti C, Sorcini D, Varasano E, Cecchini D, Zei T, Di Tommaso A, Rosati E, Alexe G, Roti G, Stegmaier K, Di Ianni M, Falzetti F, Sportoletti P. Baldoni S, et al. Among authors: de falco f. Int J Cancer. 2018 Aug 15;143(4):958-970. doi: 10.1002/ijc.31355. Epub 2018 Mar 23. Int J Cancer. 2018. PMID: 29508386 Free PMC article.
NOTCH1 Is Aberrantly Activated in Chronic Lymphocytic Leukemia Hematopoietic Stem Cells.
Di Ianni M, Baldoni S, Del Papa B, Aureli P, Dorillo E, De Falco F, Albi E, Varasano E, Di Tommaso A, Giancola R, Accorsi P, Rotta G, Rompietti C, Silva Barcelos EC, Campese AF, Di Bartolomeo P, Screpanti I, Rosati E, Falzetti F, Sportoletti P. Di Ianni M, et al. Among authors: de falco f. Front Oncol. 2018 Apr 20;8:105. doi: 10.3389/fonc.2018.00105. eCollection 2018. Front Oncol. 2018. PMID: 29732315 Free PMC article.
NOTCH1 Aberrations in Chronic Lymphocytic Leukemia.
Rosati E, Baldoni S, De Falco F, Del Papa B, Dorillo E, Rompietti C, Albi E, Falzetti F, Di Ianni M, Sportoletti P. Rosati E, et al. Among authors: de falco f. Front Oncol. 2018 Jun 27;8:229. doi: 10.3389/fonc.2018.00229. eCollection 2018. Front Oncol. 2018. PMID: 29998084 Free PMC article. Review.
Decreased NOTCH1 Activation Correlates with Response to Ibrutinib in Chronic Lymphocytic Leukemia.
Del Papa B, Baldoni S, Dorillo E, De Falco F, Rompietti C, Cecchini D, Cantelmi MG, Sorcini D, Nogarotto M, Adamo FM, Mezzasoma F, Silva Barcelos EC, Albi E, Iacucci Ostini R, Di Tommaso A, Marra A, Montanaro G, Martelli MP, Falzetti F, Di Ianni M, Rosati E, Sportoletti P. Del Papa B, et al. Among authors: de falco f. Clin Cancer Res. 2019 Dec 15;25(24):7540-7553. doi: 10.1158/1078-0432.CCR-19-1009. Epub 2019 Oct 2. Clin Cancer Res. 2019. PMID: 31578228
NOTCH1 inhibition prevents GvHD and maintains GvL effect in murine models.
Baldoni S, Ruggeri L, Del Papa B, Sorcini D, Guardalupi F, Ulbar F, Marra A, Dorillo E, Stella A, Giancola R, Fabi B, Sola R, Ciardelli S, De Falco F, Rompietti C, Adamo FM, Rosati E, Pierini A, Sorrentino C, Sportoletti P, Di Ianni M. Baldoni S, et al. Among authors: de falco f. Bone Marrow Transplant. 2021 Aug;56(8):2019-2023. doi: 10.1038/s41409-021-01297-8. Epub 2021 Apr 19. Bone Marrow Transplant. 2021. PMID: 33875813 No abstract available.
194 results