Migueles SA - Search Results

1

Concurrent measures of total and integrated HIV DNA monitor reservoirs and ongoing replication in eradication trials.

Mexas AM, Graf EH, Pace MJ, Yu JJ, Papasavvas E, Azzoni L, Busch MP, Di Mascio M, Foulkes AS, Migueles SA, Montaner LJ, O'Doherty U. Mexas AM, et al. Among authors: migueles sa. AIDS. 2012 Nov 28;26(18):2295-306. doi: 10.1097/QAD.0b013e32835a5c2f. AIDS. 2012. PMID: 23014521 Free PMC article.

2

Elite suppressors harbor low levels of integrated HIV DNA and high levels of 2-LTR circular HIV DNA compared to HIV+ patients on and off HAART.

Graf EH, Mexas AM, Yu JJ, Shaheen F, Liszewski MK, Di Mascio M, Migueles SA, Connors M, O'Doherty U. Graf EH, et al. Among authors: migueles sa. PLoS Pathog. 2011 Feb;7(2):e1001300. doi: 10.1371/journal.ppat.1001300. Epub 2011 Feb 24. PLoS Pathog. 2011. PMID: 21383972 Free PMC article.

3

Qualitative features of the HIV-specific CD8+ T-cell response associated with immunologic control.

Hersperger AR, Migueles SA, Betts MR, Connors M. Hersperger AR, et al. Among authors: migueles sa. Curr Opin HIV AIDS. 2011 May;6(3):169-73. doi: 10.1097/COH.0b013e3283454c39. Curr Opin HIV AIDS. 2011. PMID: 21399496 Free PMC article. Review.

4

Comprehensive analysis of unique cases with extraordinary control over HIV replication.

Mendoza D, Johnson SA, Peterson BA, Natarajan V, Salgado M, Dewar RL, Burbelo PD, Doria-Rose NA, Graf EH, Greenwald JH, Hodge JN, Thompson WL, Cogliano NA, Chairez CL, Rehm CA, Jones S, Hallahan CW, Kovacs JA, Sereti I, Sued O, Peel SA, O'Connell RJ, O'Doherty U, Chun TW, Connors M, Migueles SA. Mendoza D, et al. Among authors: migueles sa. Blood. 2012 May 17;119(20):4645-55. doi: 10.1182/blood-2011-10-381996. Epub 2012 Apr 5. Blood. 2012. PMID: 22490332 Free PMC article.

5

Gag-positive reservoir cells are susceptible to HIV-specific cytotoxic T lymphocyte mediated clearance in vitro and can be detected in vivo [corrected].

Graf EH, Pace MJ, Peterson BA, Lynch LJ, Chukwulebe SB, Mexas AM, Shaheen F, Martin JN, Deeks SG, Connors M, Migueles SA, O'Doherty U. Graf EH, et al. Among authors: migueles sa. PLoS One. 2013 Aug 7;8(8):e71879. doi: 10.1371/journal.pone.0071879. eCollection 2013. PLoS One. 2013. PMID: 23951263 Free PMC article.

6

A Subset of CD4/CD8 Double-Negative T Cells Expresses HIV Proteins in Patients on Antiretroviral Therapy.

DeMaster LK, Liu X, VanBelzen DJ, Trinité B, Zheng L, Agosto LM, Migueles SA, Connors M, Sambucetti L, Levy DN, Pasternak AO, O'Doherty U. DeMaster LK, et al. Among authors: migueles sa. J Virol. 2015 Nov 4;90(5):2165-79. doi: 10.1128/JVI.01913-15. J Virol. 2015. PMID: 26537682 Free PMC article.

7

Monitoring Integration over Time Supports a Role for Cytotoxic T Lymphocytes and Ongoing Replication as Determinants of Reservoir Size.

Pinzone MR, Graf E, Lynch L, McLaughlin B, Hecht FM, Connors M, Migueles SA, Hwang WT, Nunnari G, O'Doherty U. Pinzone MR, et al. Among authors: migueles sa. J Virol. 2016 Nov 14;90(23):10436-10445. doi: 10.1128/JVI.00242-16. Print 2016 Dec 1. J Virol. 2016. PMID: 27630237 Free PMC article.

8

Longitudinal HIV sequencing reveals reservoir expression leading to decay which is obscured by clonal expansion.

Pinzone MR, VanBelzen DJ, Weissman S, Bertuccio MP, Cannon L, Venanzi-Rullo E, Migueles S, Jones RB, Mota T, Joseph SB, Groen K, Pasternak AO, Hwang WT, Sherman B, Vourekas A, Nunnari G, O'Doherty U. Pinzone MR, et al. Nat Commun. 2019 Feb 13;10(1):728. doi: 10.1038/s41467-019-08431-7. Nat Commun. 2019. PMID: 30760706 Free PMC article.

9

Naive infection predicts reservoir diversity and is a formidable hurdle to HIV eradication.

Pinzone MR, Weissman S, Pasternak AO, Zurakowski R, Migueles S, O'Doherty U. Pinzone MR, et al. JCI Insight. 2021 Aug 23;6(16):e150794. doi: 10.1172/jci.insight.150794. JCI Insight. 2021. PMID: 34228640 Free PMC article.

10

HLA B*5701 is highly associated with restriction of virus replication in a subgroup of HIV-infected long term nonprogressors.

Migueles SA, Sabbaghian MS, Shupert WL, Bettinotti MP, Marincola FM, Martino L, Hallahan CW, Selig SM, Schwartz D, Sullivan J, Connors M. Migueles SA, et al. Proc Natl Acad Sci U S A. 2000 Mar 14;97(6):2709-14. doi: 10.1073/pnas.050567397. Proc Natl Acad Sci U S A. 2000. PMID: 10694578 Free PMC article.

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