Shen R - Search Results

1

Molecular epidemiology of EGFR and KRAS mutations in 3,026 lung adenocarcinomas: higher susceptibility of women to smoking-related KRAS-mutant cancers.

Dogan S, Shen R, Ang DC, Johnson ML, D'Angelo SP, Paik PK, Brzostowski EB, Riely GJ, Kris MG, Zakowski MF, Ladanyi M. Dogan S, et al. Among authors: shen r. Clin Cancer Res. 2012 Nov 15;18(22):6169-77. doi: 10.1158/1078-0432.CCR-11-3265. Epub 2012 Sep 26. Clin Cancer Res. 2012. PMID: 23014527 Free PMC article.

2

Integrative clustering of multiple genomic data types using a joint latent variable model with application to breast and lung cancer subtype analysis.

Shen R, Olshen AB, Ladanyi M. Shen R, et al. Bioinformatics. 2009 Nov 15;25(22):2906-12. doi: 10.1093/bioinformatics/btp543. Epub 2009 Sep 16. Bioinformatics. 2009. PMID: 19759197 Free PMC article.

3

Dual targeting of EGFR can overcome a major drug resistance mutation in mouse models of EGFR mutant lung cancer.

Regales L, Gong Y, Shen R, de Stanchina E, Vivanco I, Goel A, Koutcher JA, Spassova M, Ouerfelli O, Mellinghoff IK, Zakowski MF, Politi KA, Pao W. Regales L, et al. Among authors: shen r. J Clin Invest. 2009 Oct;119(10):3000-10. doi: 10.1172/JCI38746. Epub 2009 Sep 14. J Clin Invest. 2009. PMID: 19759520 Free PMC article.

4

High expression levels of total IGF-1R and sensitivity of NSCLC cells in vitro to an anti-IGF-1R antibody (R1507).

Gong Y, Yao E, Shen R, Goel A, Arcila M, Teruya-Feldstein J, Zakowski MF, Frankel S, Peifer M, Thomas RK, Ladanyi M, Pao W. Gong Y, et al. Among authors: shen r. PLoS One. 2009 Oct 6;4(10):e7273. doi: 10.1371/journal.pone.0007273. PLoS One. 2009. PMID: 19806209 Free PMC article.

5

Comprehensive genomic analysis reveals clinically relevant molecular distinctions between thymic carcinomas and thymomas.

Girard N, Shen R, Guo T, Zakowski MF, Heguy A, Riely GJ, Huang J, Lau C, Lash AE, Ladanyi M, Viale A, Antonescu CR, Travis WD, Rusch VW, Kris MG, Pao W. Girard N, et al. Among authors: shen r. Clin Cancer Res. 2009 Nov 15;15(22):6790-9. doi: 10.1158/1078-0432.CCR-09-0644. Epub 2009 Oct 27. Clin Cancer Res. 2009. PMID: 19861435 Free PMC article.

6

Erlotinib resistance in mouse models of epidermal growth factor receptor-induced lung adenocarcinoma.

Politi K, Fan PD, Shen R, Zakowski M, Varmus H. Politi K, et al. Among authors: shen r. Dis Model Mech. 2010 Jan-Feb;3(1-2):111-9. doi: 10.1242/dmm.003681. Epub 2009 Dec 9. Dis Model Mech. 2010. PMID: 20007486 Free PMC article.

7

Pack-years of cigarette smoking as a prognostic factor in patients with stage IIIB/IV nonsmall cell lung cancer.

Janjigian YY, McDonnell K, Kris MG, Shen R, Sima CS, Bach PB, Rizvi NA, Riely GJ. Janjigian YY, et al. Among authors: shen r. Cancer. 2010 Feb 1;116(3):670-5. doi: 10.1002/cncr.24813. Cancer. 2010. PMID: 20029977 Free PMC article.

8

Impact on disease-free survival of adjuvant erlotinib or gefitinib in patients with resected lung adenocarcinomas that harbor EGFR mutations.

Janjigian YY, Park BJ, Zakowski MF, Ladanyi M, Pao W, D'Angelo SP, Kris MG, Shen R, Zheng J, Azzoli CG. Janjigian YY, et al. Among authors: shen r. J Thorac Oncol. 2011 Mar;6(3):569-75. doi: 10.1097/JTO.0b013e318202bffe. J Thorac Oncol. 2011. PMID: 21150674 Free PMC article.

9

Molecular characteristics predict clinical outcomes: prospective trial correlating response to the EGFR tyrosine kinase inhibitor gefitinib with the presence of sensitizing mutations in the tyrosine binding domain of the EGFR gene.

Rizvi NA, Rusch V, Pao W, Chaft JE, Ladanyi M, Miller VA, Krug LM, Azzoli CG, Bains M, Downey R, Flores R, Park B, Singh B, Zakowski M, Heelan RT, Shen R, Kris MG. Rizvi NA, et al. Among authors: shen r. Clin Cancer Res. 2011 May 15;17(10):3500-6. doi: 10.1158/1078-0432.CCR-10-2102. Epub 2011 May 10. Clin Cancer Res. 2011. PMID: 21558399 Free PMC article. Clinical Trial.

10

The nuclear deubiquitinase BAP1 is commonly inactivated by somatic mutations and 3p21.1 losses in malignant pleural mesothelioma.

Bott M, Brevet M, Taylor BS, Shimizu S, Ito T, Wang L, Creaney J, Lake RA, Zakowski MF, Reva B, Sander C, Delsite R, Powell S, Zhou Q, Shen R, Olshen A, Rusch V, Ladanyi M. Bott M, et al. Among authors: shen r. Nat Genet. 2011 Jun 5;43(7):668-72. doi: 10.1038/ng.855. Nat Genet. 2011. PMID: 21642991 Free PMC article.

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