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Convergent animal and human evidence suggests a role of PPM1A gene in response to antidepressants.
Malki K, Uher R, Paya-Cano J, Binder E, Rietschel M, Zobel A, Mors O, Hauser J, Henigsberg N, Jerman B, Souery D, Placentino A, Ng MY, Cohen-Woods S, Sluyter F, Farmer A, Aitchison KJ, Craig IW, Lewis CM, McGuffin P, Schalkwyk LC. Malki K, et al. Among authors: mcguffin p. Biol Psychiatry. 2011 Feb 15;69(4):360-5. doi: 10.1016/j.biopsych.2010.08.011. Epub 2010 Oct 20. Biol Psychiatry. 2011. PMID: 20970119 Clinical Trial.
Highly polygenic architecture of antidepressant treatment response: Comparative analysis of SSRI and NRI treatment in an animal model of depression.
Malki K, Tosto MG, Mouriño-Talín H, Rodríguez-Lorenzo S, Pain O, Jumhaboy I, Liu T, Parpas P, Newman S, Malykh A, Carboni L, Uher R, McGuffin P, Schalkwyk LC, Bryson K, Herbster M. Malki K, et al. Among authors: mcguffin p. Am J Med Genet B Neuropsychiatr Genet. 2017 Apr;174(3):235-250. doi: 10.1002/ajmg.b.32494. Epub 2016 Oct 1. Am J Med Genet B Neuropsychiatr Genet. 2017. PMID: 27696737 Free PMC article.
Genetic predictors of response to antidepressants in the GENDEP project.
Uher R, Huezo-Diaz P, Perroud N, Smith R, Rietschel M, Mors O, Hauser J, Maier W, Kozel D, Henigsberg N, Barreto M, Placentino A, Dernovsek MZ, Schulze TG, Kalember P, Zobel A, Czerski PM, Larsen ER, Souery D, Giovannini C, Gray JM, Lewis CM, Farmer A, Aitchison KJ, McGuffin P, Craig I. Uher R, et al. Among authors: mcguffin p. Pharmacogenomics J. 2009 Aug;9(4):225-33. doi: 10.1038/tpj.2009.12. Epub 2009 Apr 14. Pharmacogenomics J. 2009. PMID: 19365399
Moderation of antidepressant response by the serotonin transporter gene.
Huezo-Diaz P, Uher R, Smith R, Rietschel M, Henigsberg N, Marusic A, Mors O, Maier W, Hauser J, Souery D, Placentino A, Zobel A, Larsen ER, Czerski PM, Gupta B, Hoda F, Perroud N, Farmer A, Craig I, Aitchison KJ, McGuffin P. Huezo-Diaz P, et al. Among authors: mcguffin p. Br J Psychiatry. 2009 Jul;195(1):30-8. doi: 10.1192/bjp.bp.108.062521. Br J Psychiatry. 2009. PMID: 19567893 Clinical Trial.
Genetic predictors of increase in suicidal ideation during antidepressant treatment in the GENDEP project.
Perroud N, Aitchison KJ, Uher R, Smith R, Huezo-Diaz P, Marusic A, Maier W, Mors O, Placentino A, Henigsberg N, Rietschel M, Hauser J, Souery D, Kapelski P, Bonvicini C, Zobel A, Jorgensen L, Petrovic A, Kalember P, Schulze TG, Gupta B, Gray J, Lewis CM, Farmer AE, McGuffin P, Craig I. Perroud N, et al. Among authors: mcguffin p. Neuropsychopharmacology. 2009 Nov;34(12):2517-28. doi: 10.1038/npp.2009.81. Epub 2009 Jul 29. Neuropsychopharmacology. 2009. PMID: 19641488 Clinical Trial.
Genome-wide pharmacogenetics of antidepressant response in the GENDEP project.
Uher R, Perroud N, Ng MY, Hauser J, Henigsberg N, Maier W, Mors O, Placentino A, Rietschel M, Souery D, Zagar T, Czerski PM, Jerman B, Larsen ER, Schulze TG, Zobel A, Cohen-Woods S, Pirlo K, Butler AW, Muglia P, Barnes MR, Lathrop M, Farmer A, Breen G, Aitchison KJ, Craig I, Lewis CM, McGuffin P. Uher R, et al. Among authors: mcguffin p. Am J Psychiatry. 2010 May;167(5):555-64. doi: 10.1176/appi.ajp.2009.09070932. Epub 2010 Apr 1. Am J Psychiatry. 2010. PMID: 20360315
625 results