Lu K - Search Results

1

CKIP-1 couples Smurf1 ubiquitin ligase with Rpt6 subunit of proteasome to promote substrate degradation.

Wang Y, Nie J, Wang Y, Zhang L, Lu K, Xing G, Xie P, He F, Zhang L. Wang Y, et al. Among authors: lu k. EMBO Rep. 2012 Nov 6;13(11):1004-11. doi: 10.1038/embor.2012.144. Epub 2012 Oct 2. EMBO Rep. 2012. PMID: 23032291 Free PMC article.

2

Targeting WW domains linker of HECT-type ubiquitin ligase Smurf1 for activation by CKIP-1.

Lu K, Yin X, Weng T, Xi S, Li L, Xing G, Cheng X, Yang X, Zhang L, He F. Lu K, et al. Nat Cell Biol. 2008 Aug;10(8):994-1002. doi: 10.1038/ncb1760. Epub 2008 Jul 20. Nat Cell Biol. 2008. PMID: 18641638

3

Ubiquitin ligase Smurf1 targets TRAF family proteins for ubiquitination and degradation.

Li S, Lu K, Wang J, An L, Yang G, Chen H, Cui Y, Yin X, Xie P, Xing G, He F, Zhang L. Li S, et al. Among authors: lu k. Mol Cell Biochem. 2010 May;338(1-2):11-7. doi: 10.1007/s11010-009-0315-y. Epub 2009 Nov 24. Mol Cell Biochem. 2010. PMID: 19937093

4

Pivotal role of the C2 domain of the Smurf1 ubiquitin ligase in substrate selection.

Lu K, Li P, Zhang M, Xing G, Li X, Zhou W, Bartlam M, Zhang L, Rao Z, He F. Lu K, et al. J Biol Chem. 2011 May 13;286(19):16861-70. doi: 10.1074/jbc.M110.211979. Epub 2011 Mar 14. J Biol Chem. 2011. PMID: 21402695 Free PMC article.

5

SCFFBXL¹⁵ regulates BMP signalling by directing the degradation of HECT-type ubiquitin ligase Smurf1.

Cui Y, He S, Xing C, Lu K, Wang J, Xing G, Meng A, Jia S, He F, Zhang L. Cui Y, et al. Among authors: lu k. EMBO J. 2011 May 13;30(13):2675-89. doi: 10.1038/emboj.2011.155. EMBO J. 2011. PMID: 21572392 Free PMC article.

6

Selective small molecule compounds increase BMP-2 responsiveness by inhibiting Smurf1-mediated Smad1/5 degradation.

Cao Y, Wang C, Zhang X, Xing G, Lu K, Gu Y, He F, Zhang L. Cao Y, et al. Among authors: lu k. Sci Rep. 2014 May 14;4:4965. doi: 10.1038/srep04965. Sci Rep. 2014. PMID: 24828823 Free PMC article.

7

Histone methyltransferase protein SETD2 interacts with p53 and selectively regulates its downstream genes.

Xie P, Tian C, An L, Nie J, Lu K, Xing G, Zhang L, He F. Xie P, et al. Among authors: lu k. Cell Signal. 2008 Sep;20(9):1671-8. doi: 10.1016/j.cellsig.2008.05.012. Epub 2008 Jun 27. Cell Signal. 2008. PMID: 18585004

8

KRAB-type zinc-finger protein Apak specifically regulates p53-dependent apoptosis.

Tian C, Xing G, Xie P, Lu K, Nie J, Wang J, Li L, Gao M, Zhang L, He F. Tian C, et al. Among authors: lu k. Nat Cell Biol. 2009 May;11(5):580-91. doi: 10.1038/ncb1864. Epub 2009 Apr 19. Nat Cell Biol. 2009. PMID: 19377469

9

N-terminal PH domain and C-terminal auto-inhibitory region of CKIP-1 coordinate to determine its nucleus-plasma membrane shuttling.

Xi S, Tie Y, Lu K, Zhang M, Yin X, Chen J, Xing G, Tian C, Zheng X, He F, Zhang L. Xi S, et al. Among authors: lu k. FEBS Lett. 2010 Mar 19;584(6):1223-30. doi: 10.1016/j.febslet.2010.02.036. Epub 2010 Feb 18. FEBS Lett. 2010. PMID: 20171213 Free article.

10

The HECT type ubiquitin ligase NEDL2 is degraded by anaphase-promoting complex/cyclosome (APC/C)-Cdh1, and its tight regulation maintains the metaphase to anaphase transition.

Lu L, Hu S, Wei R, Qiu X, Lu K, Fu Y, Li H, Xing G, Li D, Peng R, He F, Zhang L. Lu L, et al. Among authors: lu k. J Biol Chem. 2013 Dec 13;288(50):35637-50. doi: 10.1074/jbc.M113.472076. Epub 2013 Oct 25. J Biol Chem. 2013. PMID: 24163370 Free PMC article.

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