Chacon J - Search Results

1

Specific lymphocyte subsets predict response to adoptive cell therapy using expanded autologous tumor-infiltrating lymphocytes in metastatic melanoma patients.

Radvanyi LG, Bernatchez C, Zhang M, Fox PS, Miller P, Chacon J, Wu R, Lizee G, Mahoney S, Alvarado G, Glass M, Johnson VE, McMannis JD, Shpall E, Prieto V, Papadopoulos N, Kim K, Homsi J, Bedikian A, Hwu WJ, Patel S, Ross MI, Lee JE, Gershenwald JE, Lucci A, Royal R, Cormier JN, Davies MA, Mansaray R, Fulbright OJ, Toth C, Ramachandran R, Wardell S, Gonzalez A, Hwu P. Radvanyi LG, et al. Among authors: chacon j. Clin Cancer Res. 2012 Dec 15;18(24):6758-70. doi: 10.1158/1078-0432.CCR-12-1177. Epub 2012 Oct 2. Clin Cancer Res. 2012. PMID: 23032743 Free PMC article. Clinical Trial.

2

Detection and characterization of a novel subset of CD8⁺CD57⁺ T cells in metastatic melanoma with an incompletely differentiated phenotype.

Wu RC, Liu S, Chacon JA, Wu S, Li Y, Sukhumalchandra P, Murray JL, Molldrem JJ, Hwu P, Pircher H, Lizée G, Radvanyi LG. Wu RC, et al. Among authors: chacon ja. Clin Cancer Res. 2012 May 1;18(9):2465-77. doi: 10.1158/1078-0432.CCR-11-2034. Epub 2012 Feb 3. Clin Cancer Res. 2012. PMID: 22307139 Free PMC article.

3

Adoptive T-cell therapy using autologous tumor-infiltrating lymphocytes for metastatic melanoma: current status and future outlook.

Wu R, Forget MA, Chacon J, Bernatchez C, Haymaker C, Chen JQ, Hwu P, Radvanyi LG. Wu R, et al. Among authors: chacon j. Cancer J. 2012 Mar-Apr;18(2):160-75. doi: 10.1097/PPO.0b013e31824d4465. Cancer J. 2012. PMID: 22453018 Free PMC article. Review.

4

Co-stimulation through 4-1BB/CD137 improves the expansion and function of CD8(+) melanoma tumor-infiltrating lymphocytes for adoptive T-cell therapy.

Chacon JA, Wu RC, Sukhumalchandra P, Molldrem JJ, Sarnaik A, Pilon-Thomas S, Weber J, Hwu P, Radvanyi L. Chacon JA, et al. PLoS One. 2013;8(4):e60031. doi: 10.1371/journal.pone.0060031. Epub 2013 Apr 1. PLoS One. 2013. PMID: 23560068 Free PMC article.

5

Continuous 4-1BB co-stimulatory signals for the optimal expansion of tumor-infiltrating lymphocytes for adoptive T-cell therapy.

Chacon JA, Pilon-Thomas S, Sarnaik AA, Radvanyi LG. Chacon JA, et al. Oncoimmunology. 2013 Sep 1;2(9):e25581. doi: 10.4161/onci.25581. Epub 2013 Jul 3. Oncoimmunology. 2013. PMID: 24319633 Free PMC article.

6

Tumor-infiltrating lymphocyte therapy for melanoma: rationale and issues for further clinical development.

Sim GC, Chacon J, Haymaker C, Ritthipichai K, Singh M, Hwu P, Radvanyi L. Sim GC, et al. Among authors: chacon j. BioDrugs. 2014 Oct;28(5):421-37. doi: 10.1007/s40259-014-0097-y. BioDrugs. 2014. PMID: 24890028 Review.

7

Manipulating the tumor microenvironment ex vivo for enhanced expansion of tumor-infiltrating lymphocytes for adoptive cell therapy.

Chacon JA, Sarnaik AA, Chen JQ, Creasy C, Kale C, Robinson J, Weber J, Hwu P, Pilon-Thomas S, Radvanyi L. Chacon JA, et al. Clin Cancer Res. 2015 Feb 1;21(3):611-21. doi: 10.1158/1078-0432.CCR-14-1934. Epub 2014 Dec 3. Clin Cancer Res. 2015. PMID: 25472998 Free PMC article.

8

Triggering co-stimulation directly in melanoma tumor fragments drives CD8⁺ tumor-infiltrating lymphocyte expansion with improved effector-memory properties.

Chacon JA, Sarnaik AA, Pilon-Thomas S, Radvanyi L. Chacon JA, et al. Oncoimmunology. 2015 Jul 1;4(12):e1040219. doi: 10.1080/2162402X.2015.1040219. eCollection 2015 Dec. Oncoimmunology. 2015. PMID: 26587314 Free PMC article.

9

4-1BB-Enhanced Expansion of CD8⁺ TIL from Triple-Negative Breast Cancer Unveils Mutation-Specific CD8⁺ T Cells.

Harao M, Forget MA, Roszik J, Gao H, Babiera GV, Krishnamurthy S, Chacon JA, Li S, Mittendorf EA, DeSnyder SM, Rockwood KF, Bernatchez C, Ueno NT, Radvanyi LG, Vence L, Haymaker C, Reuben JM. Harao M, et al. Among authors: chacon ja. Cancer Immunol Res. 2017 Jun;5(6):439-445. doi: 10.1158/2326-6066.CIR-16-0364. Epub 2017 May 4. Cancer Immunol Res. 2017. PMID: 28473315 Free PMC article.

10

Effective adoptive immunotherapy of triple-negative breast cancer by folate receptor-alpha redirected CAR T cells is influenced by surface antigen expression level.

Song DG, Ye Q, Poussin M, Chacon JA, Figini M, Powell DJ Jr. Song DG, et al. Among authors: chacon ja. J Hematol Oncol. 2016 Jul 20;9(1):56. doi: 10.1186/s13045-016-0285-y. J Hematol Oncol. 2016. PMID: 27439908 Free PMC article.

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