Samadi A - Search Results

1

Minor withanolides of Physalis longifolia: structure and cytotoxicity.

Zhang H, Motiwala H, Samadi A, Day V, Aubé J, Cohen M, Kindscher K, Gollapudi R, Timmermann B. Zhang H, et al. Among authors: samadi a. Chem Pharm Bull (Tokyo). 2012;60(10):1234-9. doi: 10.1248/cpb.c12-00305. Chem Pharm Bull (Tokyo). 2012. PMID: 23036966 Free PMC article.

2

Withaferin A, a cytotoxic steroid from Vassobia breviflora, induces apoptosis in human head and neck squamous cell carcinoma.

Samadi AK, Tong X, Mukerji R, Zhang H, Timmermann BN, Cohen MS. Samadi AK, et al. J Nat Prod. 2010 Sep 24;73(9):1476-81. doi: 10.1021/np100112p. J Nat Prod. 2010. PMID: 20726569 Free PMC article.

3

Cytotoxic oleanane-type saponins from Albizia inundata.

Zhang H, Samadi AK, Rao KV, Cohen MS, Timmermann BN. Zhang H, et al. J Nat Prod. 2011 Mar 25;74(3):477-82. doi: 10.1021/np100702p. Epub 2011 Feb 11. J Nat Prod. 2011. PMID: 21314099 Free PMC article.

4

Cytotoxic withanolide constituents of Physalis longifolia.

Zhang H, Samadi AK, Gallagher RJ, Araya JJ, Tong X, Day VW, Cohen MS, Kindscher K, Gollapudi R, Timmermann BN. Zhang H, et al. J Nat Prod. 2011 Dec 27;74(12):2532-44. doi: 10.1021/np200635r. Epub 2011 Nov 18. J Nat Prod. 2011. PMID: 22098611 Free PMC article.

5

Novel withanolides target medullary thyroid cancer through inhibition of both RET phosphorylation and the mammalian target of rapamycin pathway.

Samadi AK, Bazzill J, Zhang X, Gallagher R, Zhang H, Gollapudi R, Kindscher K, Timmermann B, Cohen MS. Samadi AK, et al. Surgery. 2012 Dec;152(6):1238-47. doi: 10.1016/j.surg.2012.08.031. Surgery. 2012. PMID: 23158190 Free PMC article.

6

Anti-proliferative withanolides from the Solanaceae: a structure-activity study.

Zhang H, Samadi AK, Cohen MS, Timmermann BN. Zhang H, et al. Pure Appl Chem. 2012;84(6):1353-1367. doi: 10.1351/PAC-CON-11-10-08. Pure Appl Chem. 2012. PMID: 24098060 Free PMC article.

7

A novel RET inhibitor with potent efficacy against medullary thyroid cancer in vivo.

Samadi AK, Mukerji R, Shah A, Timmermann BN, Cohen MS. Samadi AK, et al. Surgery. 2010 Dec;148(6):1228-36; discussion 1236. doi: 10.1016/j.surg.2010.09.026. Surgery. 2010. PMID: 21134556 Free PMC article.

8

Natural withanolide withaferin A induces apoptosis in uveal melanoma cells by suppression of Akt and c-MET activation.

Samadi AK, Cohen SM, Mukerji R, Chaguturu V, Zhang X, Timmermann BN, Cohen MS, Person EA. Samadi AK, et al. Tumour Biol. 2012 Aug;33(4):1179-89. doi: 10.1007/s13277-012-0363-x. Epub 2012 Apr 5. Tumour Biol. 2012. PMID: 22477711

9

Cytotoxicity of withaferin A in glioblastomas involves induction of an oxidative stress-mediated heat shock response while altering Akt/mTOR and MAPK signaling pathways.

Grogan PT, Sleder KD, Samadi AK, Zhang H, Timmermann BN, Cohen MS. Grogan PT, et al. Invest New Drugs. 2013 Jun;31(3):545-57. doi: 10.1007/s10637-012-9888-5. Epub 2012 Nov 6. Invest New Drugs. 2013. PMID: 23129310 Free PMC article.

10

A novel combination of withaferin A and sorafenib shows synergistic efficacy against both papillary and anaplastic thyroid cancers.

Cohen SM, Mukerji R, Timmermann BN, Samadi AK, Cohen MS. Cohen SM, et al. Am J Surg. 2012 Dec;204(6):895-900; discussion 900-1. doi: 10.1016/j.amjsurg.2012.07.027. Am J Surg. 2012. PMID: 23231932

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