Mangelsdorf DJ - Search Results

1

Nuclear receptors HNF4α and LRH-1 cooperate in regulating Cyp7a1 in vivo.

Kir S, Zhang Y, Gerard RD, Kliewer SA, Mangelsdorf DJ. Kir S, et al. Among authors: mangelsdorf dj. J Biol Chem. 2012 Nov 30;287(49):41334-41. doi: 10.1074/jbc.M112.421834. Epub 2012 Oct 4. J Biol Chem. 2012. PMID: 23038264 Free PMC article.

2

Fibroblast growth factor 15 functions as an enterohepatic signal to regulate bile acid homeostasis.

Inagaki T, Choi M, Moschetta A, Peng L, Cummins CL, McDonald JG, Luo G, Jones SA, Goodwin B, Richardson JA, Gerard RD, Repa JJ, Mangelsdorf DJ, Kliewer SA. Inagaki T, et al. Among authors: mangelsdorf dj. Cell Metab. 2005 Oct;2(4):217-25. doi: 10.1016/j.cmet.2005.09.001. Cell Metab. 2005. PMID: 16213224 Free article.

3

FXR agonists and FGF15 reduce fecal bile acid excretion in a mouse model of bile acid malabsorption.

Jung D, Inagaki T, Gerard RD, Dawson PA, Kliewer SA, Mangelsdorf DJ, Moschetta A. Jung D, et al. Among authors: mangelsdorf dj. J Lipid Res. 2007 Dec;48(12):2693-700. doi: 10.1194/jlr.M700351-JLR200. Epub 2007 Sep 6. J Lipid Res. 2007. PMID: 17823457 Free article.

4

Liver receptor homolog-1 regulates bile acid homeostasis but is not essential for feedback regulation of bile acid synthesis.

Lee YK, Schmidt DR, Cummins CL, Choi M, Peng L, Zhang Y, Goodwin B, Hammer RE, Mangelsdorf DJ, Kliewer SA. Lee YK, et al. Among authors: mangelsdorf dj. Mol Endocrinol. 2008 Jun;22(6):1345-56. doi: 10.1210/me.2007-0565. Epub 2008 Mar 6. Mol Endocrinol. 2008. PMID: 18323469 Free PMC article.

5

Regulation of bile acid synthesis by fat-soluble vitamins A and D.

Schmidt DR, Holmstrom SR, Fon Tacer K, Bookout AL, Kliewer SA, Mangelsdorf DJ. Schmidt DR, et al. Among authors: mangelsdorf dj. J Biol Chem. 2010 May 7;285(19):14486-94. doi: 10.1074/jbc.M110.116004. Epub 2010 Mar 16. J Biol Chem. 2010. PMID: 20233723 Free PMC article.

6

AKR1B7 is induced by the farnesoid X receptor and metabolizes bile acids.

Schmidt DR, Schmidt S, Holmstrom SR, Makishima M, Yu RT, Cummins CL, Mangelsdorf DJ, Kliewer SA. Schmidt DR, et al. Among authors: mangelsdorf dj. J Biol Chem. 2011 Jan 28;286(4):2425-32. doi: 10.1074/jbc.M110.181230. Epub 2010 Nov 16. J Biol Chem. 2011. PMID: 21081494 Free PMC article.

7

The G protein-coupled bile acid receptor, TGR5, stimulates gallbladder filling.

Li T, Holmstrom SR, Kir S, Umetani M, Schmidt DR, Kliewer SA, Mangelsdorf DJ. Li T, et al. Among authors: mangelsdorf dj. Mol Endocrinol. 2011 Jun;25(6):1066-71. doi: 10.1210/me.2010-0460. Epub 2011 Mar 31. Mol Endocrinol. 2011. PMID: 21454404 Free PMC article.

8

Bile Acids as Hormones: The FXR-FGF15/19 Pathway.

Kliewer SA, Mangelsdorf DJ. Kliewer SA, et al. Among authors: mangelsdorf dj. Dig Dis. 2015;33(3):327-31. doi: 10.1159/000371670. Epub 2015 May 27. Dig Dis. 2015. PMID: 26045265 Free PMC article. Review.

9

LuXuRies of lipid homeostasis: the unity of nuclear hormone receptors, transcription regulation, and cholesterol sensing.

Zhang Y, Mangelsdorf DJ. Zhang Y, et al. Among authors: mangelsdorf dj. Mol Interv. 2002 Apr;2(2):78-87. doi: 10.1124/mi.2.2.78. Mol Interv. 2002. PMID: 14993353 Review.

10

Regulation of lipoprotein lipase by the oxysterol receptors, LXRalpha and LXRbeta.

Zhang Y, Repa JJ, Gauthier K, Mangelsdorf DJ. Zhang Y, et al. Among authors: mangelsdorf dj. J Biol Chem. 2001 Nov 16;276(46):43018-24. doi: 10.1074/jbc.M107823200. Epub 2001 Sep 18. J Biol Chem. 2001. PMID: 11562371 Free article.

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