Frezza C - Search Results

1

Serine is a natural ligand and allosteric activator of pyruvate kinase M2.

Chaneton B, Hillmann P, Zheng L, Martin ACL, Maddocks ODK, Chokkathukalam A, Coyle JE, Jankevics A, Holding FP, Vousden KH, Frezza C, O'Reilly M, Gottlieb E. Chaneton B, et al. Among authors: frezza c. Nature. 2012 Nov 15;491(7424):458-462. doi: 10.1038/nature11540. Epub 2012 Oct 14. Nature. 2012. PMID: 23064226 Free PMC article.

2

Mitochondria in cancer: not just innocent bystanders.

Frezza C, Gottlieb E. Frezza C, et al. Semin Cancer Biol. 2009 Feb;19(1):4-11. doi: 10.1016/j.semcancer.2008.11.008. Epub 2008 Dec 3. Semin Cancer Biol. 2009. PMID: 19101633 Review.

3

Reactivating HIF prolyl hydroxylases under hypoxia results in metabolic catastrophe and cell death.

Tennant DA, Frezza C, MacKenzie ED, Nguyen QD, Zheng L, Selak MA, Roberts DL, Dive C, Watson DG, Aboagye EO, Gottlieb E. Tennant DA, et al. Among authors: frezza c. Oncogene. 2009 Nov 12;28(45):4009-21. doi: 10.1038/onc.2009.250. Epub 2009 Aug 31. Oncogene. 2009. PMID: 19718054

4

IDH1 mutations in gliomas: when an enzyme loses its grip.

Frezza C, Tennant DA, Gottlieb E. Frezza C, et al. Cancer Cell. 2010 Jan 19;17(1):7-9. doi: 10.1016/j.ccr.2009.12.031. Cancer Cell. 2010. PMID: 20129244 Free article.

5

Inborn and acquired metabolic defects in cancer.

Frezza C, Pollard PJ, Gottlieb E. Frezza C, et al. J Mol Med (Berl). 2011 Mar;89(3):213-20. doi: 10.1007/s00109-011-0728-4. Epub 2011 Feb 8. J Mol Med (Berl). 2011. PMID: 21301796 Free PMC article. Review.

6

Predicting selective drug targets in cancer through metabolic networks.

Folger O, Jerby L, Frezza C, Gottlieb E, Ruppin E, Shlomi T. Folger O, et al. Among authors: frezza c. Mol Syst Biol. 2011 Jun 21;7:501. doi: 10.1038/msb.2011.35. Mol Syst Biol. 2011. PMID: 21694718 Free PMC article.

7

Haem oxygenase is synthetically lethal with the tumour suppressor fumarate hydratase.

Frezza C, Zheng L, Folger O, Rajagopalan KN, MacKenzie ED, Jerby L, Micaroni M, Chaneton B, Adam J, Hedley A, Kalna G, Tomlinson IP, Pollard PJ, Watson DG, Deberardinis RJ, Shlomi T, Ruppin E, Gottlieb E. Frezza C, et al. Nature. 2011 Aug 17;477(7363):225-8. doi: 10.1038/nature10363. Nature. 2011. PMID: 21849978

8

Metabolic profiling of hypoxic cells revealed a catabolic signature required for cell survival.

Frezza C, Zheng L, Tennant DA, Papkovsky DB, Hedley BA, Kalna G, Watson DG, Gottlieb E. Frezza C, et al. PLoS One. 2011;6(9):e24411. doi: 10.1371/journal.pone.0024411. Epub 2011 Sep 2. PLoS One. 2011. PMID: 21912692 Free PMC article.

9

The music of lipids: how lipid composition orchestrates cellular behaviour.

Schug ZT, Frezza C, Galbraith LC, Gottlieb E. Schug ZT, et al. Among authors: frezza c. Acta Oncol. 2012 Mar;51(3):301-10. doi: 10.3109/0284186X.2011.643823. Epub 2012 Jan 30. Acta Oncol. 2012. PMID: 22283492

10

HIF-independent role of prolyl hydroxylases in the cellular response to amino acids.

Durán RV, MacKenzie ED, Boulahbel H, Frezza C, Heiserich L, Tardito S, Bussolati O, Rocha S, Hall MN, Gottlieb E. Durán RV, et al. Among authors: frezza c. Oncogene. 2013 Sep 19;32(38):4549-56. doi: 10.1038/onc.2012.465. Epub 2012 Oct 22. Oncogene. 2013. PMID: 23085753 Free PMC article.

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