Hoth LR - Search Results

1

Unexpected mucin-type O-glycosylation and host-specific N-glycosylation of human recombinant interleukin-17A expressed in a human kidney cell line.

Geoghegan KF, Song X, Hoth LR, Feng X, Shanker S, Quazi A, Luxenberg DP, Wright JF, Griffor MC. Geoghegan KF, et al. Among authors: hoth lr. Protein Expr Purif. 2013 Jan;87(1):27-34. doi: 10.1016/j.pep.2012.09.013. Epub 2012 Oct 13. Protein Expr Purif. 2013. PMID: 23069765

2

Crystal structures of interleukin 17A and its complex with IL-17 receptor A.

Liu S, Song X, Chrunyk BA, Shanker S, Hoth LR, Marr ES, Griffor MC. Liu S, et al. Among authors: hoth lr. Nat Commun. 2013;4:1888. doi: 10.1038/ncomms2880. Nat Commun. 2013. PMID: 23695682 Free article.

3

Expression and protein chemistry yielding crystallization of the catalytic domain of ADAM17 complexed with a hydroxamate inhibitor.

Hoth LR, Tan DH, Wang IK, Wengender PA, Thompson MA, Kamath AV, Geoghegan KF. Hoth LR, et al. Protein Expr Purif. 2007 Apr;52(2):313-9. doi: 10.1016/j.pep.2006.10.021. Epub 2006 Nov 7. Protein Expr Purif. 2007. PMID: 17169570

4

Escherichia coli expression, purification and characterization of functional full-length recombinant alpha2beta2gamma3 heterotrimeric complex of human AMP-activated protein kinase.

Rajamohan F, Harris MS, Frisbie RK, Hoth LR, Geoghegan KF, Valentine JJ, Reyes AR, Landro JA, Qiu X, Kurumbail RG. Rajamohan F, et al. Among authors: hoth lr. Protein Expr Purif. 2010 Oct;73(2):189-97. doi: 10.1016/j.pep.2010.04.022. Epub 2010 May 6. Protein Expr Purif. 2010. PMID: 20451617

5

Glutathione s-transferase omega 1-1 is a target of cytokine release inhibitory drugs and may be responsible for their effect on interleukin-1beta posttranslational processing.

Laliberte RE, Perregaux DG, Hoth LR, Rosner PJ, Jordan CK, Peese KM, Eggler JF, Dombroski MA, Geoghegan KF, Gabel CA. Laliberte RE, et al. Among authors: hoth lr. J Biol Chem. 2003 May 9;278(19):16567-78. doi: 10.1074/jbc.M211596200. Epub 2003 Mar 6. J Biol Chem. 2003. PMID: 12624100 Free article.

6

Binding to the low-density lipoprotein receptor accelerates futile catalytic cycling in PCSK9 and raises the equilibrium level of intramolecular acylenzyme.

Geoghegan KF, Hoth LR, Varghese AH, Lin W, Boyd JG, Griffor MC. Geoghegan KF, et al. Among authors: hoth lr. Biochemistry. 2009 Apr 7;48(13):2941-9. doi: 10.1021/bi802232m. Biochemistry. 2009. PMID: 19222187

7

Binding site elucidation and structure guided design of macrocyclic IL-17A antagonists.

Liu S, Dakin LA, Xing L, Withka JM, Sahasrabudhe PV, Li W, Banker ME, Balbo P, Shanker S, Chrunyk BA, Guo Z, Chen JM, Young JA, Bai G, Starr JT, Wright SW, Bussenius J, Tan S, Gopalsamy A, Lefker BA, Vincent F, Jones LH, Xu H, Hoth LR, Geoghegan KF, Qiu X, Bunnage ME, Thorarensen A. Liu S, et al. Among authors: hoth lr. Sci Rep. 2016 Aug 16;6:30859. doi: 10.1038/srep30859. Sci Rep. 2016. PMID: 27527709 Free PMC article.

8

Spontaneous alpha-N-6-phosphogluconoylation of a "His tag" in Escherichia coli: the cause of extra mass of 258 or 178 Da in fusion proteins.

Geoghegan KF, Dixon HB, Rosner PJ, Hoth LR, Lanzetti AJ, Borzilleri KA, Marr ES, Pezzullo LH, Martin LB, LeMotte PK, McColl AS, Kamath AV, Stroh JG. Geoghegan KF, et al. Among authors: hoth lr. Anal Biochem. 1999 Feb 1;267(1):169-84. doi: 10.1006/abio.1998.2990. Anal Biochem. 1999. PMID: 9918669

9

Dye-pair reporter systems for protein-peptide molecular interactions.

Geoghegan KF, Rosner PJ, Hoth LR. Geoghegan KF, et al. Among authors: hoth lr. Bioconjug Chem. 2000 Jan-Feb;11(1):71-7. doi: 10.1021/bc9900845. Bioconjug Chem. 2000. PMID: 10639088

10

Chemical and biochemical issues related to X-ray crystallography of the ligand-binding domain of estrogen receptor alpha.

Goldstein SW, Bordner J, Hoth LR, Geoghegan KF. Goldstein SW, et al. Among authors: hoth lr. Bioconjug Chem. 2001 May-Jun;12(3):406-13. doi: 10.1021/bc000127d. Bioconjug Chem. 2001. PMID: 11353539

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