LaVoie EJ - Search Results

1

Antibacterial activity of substituted 5-methylbenzo[c]phenanthridinium derivatives.

Parhi A, Kelley C, Kaul M, Pilch DS, LaVoie EJ. Parhi A, et al. Among authors: lavoie ej. Bioorg Med Chem Lett. 2012 Dec 1;22(23):7080-3. doi: 10.1016/j.bmcl.2012.09.097. Epub 2012 Oct 2. Bioorg Med Chem Lett. 2012. PMID: 23084900 Free PMC article.

2

Characterizing the DNA binding modes of a topoisomerase I-poisoning terbenzimidazole: evidence for both intercalative and minor groove binding properties.

Pilch DS, Xu Z, Sun Q, Lavoie EJ, Liu LF, Geacintov NE, Breslauer KJ. Pilch DS, et al. Among authors: lavoie ej. Drug Des Discov. 1996 Apr;13(3-4):115-33. Drug Des Discov. 1996. PMID: 8874049

3

Differential poisoning of topoisomerases by menogaril and nogalamycin dictated by the minor groove-binding nogalose sugar.

Sim SP, Gatto B, Yu C, Liu AA, Li TK, Pilch DS, LaVoie EJ, Liu LF. Sim SP, et al. Among authors: lavoie ej. Biochemistry. 1997 Oct 28;36(43):13285-91. doi: 10.1021/bi971261x. Biochemistry. 1997. PMID: 9341219

4

A terbenzimidazole that preferentially binds and conformationally alters structurally distinct DNA duplex domains: a potential mechanism for topoisomerase I poisoning.

Pilch DS, Xu Z, Sun Q, LaVoie EJ, Liu LF, Breslauer KJ. Pilch DS, et al. Among authors: lavoie ej. Proc Natl Acad Sci U S A. 1997 Dec 9;94(25):13565-70. doi: 10.1073/pnas.94.25.13565. Proc Natl Acad Sci U S A. 1997. PMID: 9391066 Free PMC article.

5

DNA minor groove binding-directed poisoning of human DNA topoisomerase I by terbenzimidazoles.

Xu Z, Li TK, Kim JS, LaVoie EJ, Breslauer KJ, Liu LF, Pilch DS. Xu Z, et al. Among authors: lavoie ej. Biochemistry. 1998 Mar 10;37(10):3558-66. doi: 10.1021/bi9727747. Biochemistry. 1998. PMID: 9521677

6

Heterocyclic bibenzimidazole derivatives as topoisomerase I inhibitors.

Jin S, Kim JS, Sim SP, Liu A, Pilch DS, Liu LF, LaVoie EJ. Jin S, et al. Among authors: lavoie ej. Bioorg Med Chem Lett. 2000 Apr 17;10(8):719-23. doi: 10.1016/s0960-894x(00)00087-1. Bioorg Med Chem Lett. 2000. PMID: 10782672

7

2"-Substituted 5-phenylterbenzimidazoles as topoisomerase I poisons.

Rangarajan M, Kim JS, Jin S, Sim SP, Liu A, Pilch DS, Liu LF, LaVoie EJ. Rangarajan M, et al. Among authors: lavoie ej. Bioorg Med Chem. 2000 Jun;8(6):1371-82. doi: 10.1016/s0968-0896(00)00054-7. Bioorg Med Chem. 2000. PMID: 10896114

8

2,3-Dimethoxybenzo[i]phenanthridines: topoisomerase I-targeting anticancer agents.

Li D, Zhao B, Sim SP, Li TK, Liu A, Liu LF, LaVoie EJ. Li D, et al. Among authors: lavoie ej. Bioorg Med Chem. 2003 Feb 20;11(4):521-8. doi: 10.1016/s0968-0896(02)00530-8. Bioorg Med Chem. 2003. PMID: 12538017

9

Substituted dibenzo[c,h]cinnolines: topoisomerase I-targeting anticancer agents.

Yu Y, Singh SK, Liu A, Li TK, Liu LF, LaVoie EJ. Yu Y, et al. Among authors: lavoie ej. Bioorg Med Chem. 2003 Apr 3;11(7):1475-91. doi: 10.1016/s0968-0896(02)00604-1. Bioorg Med Chem. 2003. PMID: 12628673

10

Substituted benzo[i]phenanthridines as mammalian topoisomerase-targeting agents.

Makhey D, Li D, Zhao B, Sim SP, Li TK, Liu A, Liu LF, LaVoie EJ. Makhey D, et al. Among authors: lavoie ej. Bioorg Med Chem. 2003 Apr 17;11(8):1809-20. doi: 10.1016/s0968-0896(03)00053-1. Bioorg Med Chem. 2003. PMID: 12659767

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