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The SI strain of measles virus derived from a patient with subacute sclerosing panencephalitis possesses typical genome alterations and unique amino acid changes that modulate receptor specificity and reduce membrane fusion activity.
Seki F, Yamada K, Nakatsu Y, Okamura K, Yanagi Y, Nakayama T, Komase K, Takeda M. Seki F, et al. Among authors: komase k. J Virol. 2011 Nov;85(22):11871-82. doi: 10.1128/JVI.05067-11. Epub 2011 Sep 14. J Virol. 2011. PMID: 21917959 Free PMC article.
Lethal canine distemper virus outbreak in cynomolgus monkeys in Japan in 2008.
Sakai K, Nagata N, Ami Y, Seki F, Suzaki Y, Iwata-Yoshikawa N, Suzuki T, Fukushi S, Mizutani T, Yoshikawa T, Otsuki N, Kurane I, Komase K, Yamaguchi R, Hasegawa H, Saijo M, Takeda M, Morikawa S. Sakai K, et al. Among authors: komase k. J Virol. 2013 Jan;87(2):1105-14. doi: 10.1128/JVI.02419-12. Epub 2012 Nov 7. J Virol. 2013. PMID: 23135729 Free PMC article.
The host protease TMPRSS2 plays a major role in in vivo replication of emerging H7N9 and seasonal influenza viruses.
Sakai K, Ami Y, Tahara M, Kubota T, Anraku M, Abe M, Nakajima N, Sekizuka T, Shirato K, Suzaki Y, Ainai A, Nakatsu Y, Kanou K, Nakamura K, Suzuki T, Komase K, Nobusawa E, Maenaka K, Kuroda M, Hasegawa H, Kawaoka Y, Tashiro M, Takeda M. Sakai K, et al. Among authors: komase k. J Virol. 2014 May;88(10):5608-16. doi: 10.1128/JVI.03677-13. Epub 2014 Mar 5. J Virol. 2014. PMID: 24600012 Free PMC article.
A mutant H3N2 influenza virus uses an alternative activation mechanism in TMPRSS2 knockout mice by loss of an oligosaccharide in the hemagglutinin stalk region.
Sakai K, Sekizuka T, Ami Y, Nakajima N, Kitazawa M, Sato Y, Nakajima K, Anraku M, Kubota T, Komase K, Takehara K, Hasegawa H, Odagiri T, Tashiro M, Kuroda M, Takeda M. Sakai K, et al. Among authors: komase k. J Virol. 2015 May;89(9):5154-8. doi: 10.1128/JVI.00124-15. Epub 2015 Feb 11. J Virol. 2015. PMID: 25673722 Free PMC article.
86 results