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Macrophage ABCG1 deletion disrupts lipid homeostasis in alveolar macrophages and moderately influences atherosclerotic lesion development in LDL receptor-deficient mice.
Out R, Hoekstra M, Hildebrand RB, Kruit JK, Meurs I, Li Z, Kuipers F, Van Berkel TJ, Van Eck M. Out R, et al. Among authors: hildebrand rb. Arterioscler Thromb Vasc Biol. 2006 Oct;26(10):2295-300. doi: 10.1161/01.ATV.0000237629.29842.4c. Epub 2006 Jul 20. Arterioscler Thromb Vasc Biol. 2006. PMID: 16857950
Important role for bone marrow-derived cholesteryl ester transfer protein in lipoprotein cholesterol redistribution and atherosclerotic lesion development in LDL receptor knockout mice.
Van Eck M, Ye D, Hildebrand RB, Kar Kruijt J, de Haan W, Hoekstra M, Rensen PC, Ehnholm C, Jauhiainen M, Van Berkel TJ. Van Eck M, et al. Among authors: hildebrand rb. Circ Res. 2007 Mar 16;100(5):678-85. doi: 10.1161/01.RES.0000260202.79927.4f. Epub 2007 Feb 9. Circ Res. 2007. PMID: 17293475
Combined deletion of macrophage ABCA1 and ABCG1 leads to massive lipid accumulation in tissue macrophages and distinct atherosclerosis at relatively low plasma cholesterol levels.
Out R, Hoekstra M, Habets K, Meurs I, de Waard V, Hildebrand RB, Wang Y, Chimini G, Kuiper J, Van Berkel TJ, Van Eck M. Out R, et al. Among authors: hildebrand rb. Arterioscler Thromb Vasc Biol. 2008 Feb;28(2):258-64. doi: 10.1161/ATVBAHA.107.156935. Epub 2007 Nov 15. Arterioscler Thromb Vasc Biol. 2008. PMID: 18006857
Restoration of high-density lipoprotein levels by cholesteryl ester transfer protein expression in scavenger receptor class B type I (SR-BI) knockout mice does not normalize pathologies associated with SR-BI deficiency.
Hildebrand RB, Lammers B, Meurs I, Korporaal SJ, De Haan W, Zhao Y, Kruijt JK, Praticò D, Schimmel AW, Holleboom AG, Hoekstra M, Kuivenhoven JA, Van Berkel TJ, Rensen PC, Van Eck M. Hildebrand RB, et al. Arterioscler Thromb Vasc Biol. 2010 Jul;30(7):1439-45. doi: 10.1161/ATVBAHA.110.205153. Epub 2010 Apr 29. Arterioscler Thromb Vasc Biol. 2010. PMID: 20431066
Macrophage adipose triglyceride lipase deficiency attenuates atherosclerotic lesion development in low-density lipoprotein receptor knockout mice.
Lammers B, Chandak PG, Aflaki E, Van Puijvelde GH, Radovic B, Hildebrand RB, Meurs I, Out R, Kuiper J, Van Berkel TJ, Kolb D, Haemmerle G, Zechner R, Levak-Frank S, Van Eck M, Kratky D. Lammers B, et al. Among authors: hildebrand rb. Arterioscler Thromb Vasc Biol. 2011 Jan;31(1):67-73. doi: 10.1161/ATVBAHA.110.215814. Epub 2010 Oct 28. Arterioscler Thromb Vasc Biol. 2011. PMID: 21030715 Free PMC article.
37 results