Shen J - Search Results

1

Design, synthesis, and pharmacological evaluation of monocyclic pyrimidinones as novel inhibitors of PDE5.

Wang G, Liu Z, Chen T, Wang Z, Yang H, Zheng M, Ren J, Tian G, Yang X, Li L, Li J, Suo J, Zhang R, Jiang X, Terrett NK, Shen J, Xu Y, Jiang H. Wang G, et al. Among authors: shen j. J Med Chem. 2012 Dec 13;55(23):10540-50. doi: 10.1021/jm301159y. Epub 2012 Nov 19. J Med Chem. 2012. PMID: 23137303

2

Molecular modeling on kappa opioid receptor and its interaction with nonpeptide kappa opioid agonists.

Liu DX, Jiang HL, Shen JS, Zhu WL, Zhao L, Chen KX, Ji RY. Liu DX, et al. Among authors: shen js. Zhongguo Yao Li Xue Bao. 1999 Feb;20(2):131-6. Zhongguo Yao Li Xue Bao. 1999. PMID: 10437159 Free article.

3

Brownian dynamics simulations of interaction between scorpion toxin Lq2 and potassium ion channel.

Cui M, Shen J, Briggs JM, Luo X, Tan X, Jiang H, Chen K, Ji R. Cui M, et al. Among authors: shen j. Biophys J. 2001 Apr;80(4):1659-69. doi: 10.1016/S0006-3495(01)76138-3. Biophys J. 2001. PMID: 11259281 Free PMC article.

4

Synthesis and phosphodiesterase 5 inhibitory activity of novel pyrido[1,2-e]purin-4(3H)-one derivatives.

Xia G, Li J, Peng A, Lai S, Zhang S, Shen J, Liu Z, Chen X, Ji R. Xia G, et al. Among authors: shen j. Bioorg Med Chem Lett. 2005 Jun 2;15(11):2790-4. doi: 10.1016/j.bmcl.2005.03.102. Bioorg Med Chem Lett. 2005. PMID: 15878277

5

[Spectroscopic studies of aripiprazole].

Li JF, Liu AX, Xia GX, Nian YF, Shen JS. Li JF, et al. Guang Pu Xue Yu Guang Pu Fen Xi. 2007 May;27(5):863-7. Guang Pu Xue Yu Guang Pu Fen Xi. 2007. PMID: 17655090 Chinese.

6

[Signal transduction by protein tyrosine kinases and antitumor agents].

Mao YJ, Li HH, Li JF, Shen JS. Mao YJ, et al. Yao Xue Xue Bao. 2008 Apr;43(4):323-34. Yao Xue Xue Bao. 2008. PMID: 18664191 Review. Chinese.

7

2-Phenylquinazolin-4(3H)-one, a class of potent PDE5 inhibitors with high selectivity versus PDE6.

Duan H, Zheng J, Lai Q, Liu Z, Tian G, Wang Z, Li J, Shen J. Duan H, et al. Among authors: shen j. Bioorg Med Chem Lett. 2009 May 15;19(10):2777-9. doi: 10.1016/j.bmcl.2009.03.125. Epub 2009 Mar 28. Bioorg Med Chem Lett. 2009. PMID: 19375311

8

Multiple pharmacophore models combined with molecular docking: a reliable way for efficiently identifying novel PDE4 inhibitors with high structural diversity.

Chen Z, Tian G, Wang Z, Jiang H, Shen J, Zhu W. Chen Z, et al. Among authors: shen j. J Chem Inf Model. 2010 Apr 26;50(4):615-25. doi: 10.1021/ci9004173. J Chem Inf Model. 2010. PMID: 20353193

9

Sildenafil promotes adipogenesis through a PKG pathway.

Zhang X, Ji J, Yan G, Wu J, Sun X, Shen J, Jiang H, Wang H. Zhang X, et al. Among authors: shen j. Biochem Biophys Res Commun. 2010 Jun 11;396(4):1054-9. doi: 10.1016/j.bbrc.2010.05.064. Epub 2010 May 21. Biochem Biophys Res Commun. 2010. PMID: 20471953

10

The 2009 pandemic H1N1 neuraminidase N1 lacks the 150-cavity in its active site.

Li Q, Qi J, Zhang W, Vavricka CJ, Shi Y, Wei J, Feng E, Shen J, Chen J, Liu D, He J, Yan J, Liu H, Jiang H, Teng M, Li X, Gao GF. Li Q, et al. Among authors: shen j. Nat Struct Mol Biol. 2010 Oct;17(10):1266-8. doi: 10.1038/nsmb.1909. Epub 2010 Sep 19. Nat Struct Mol Biol. 2010. PMID: 20852645

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