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Central melanin-concentrating hormone influences liver and adipose metabolism via specific hypothalamic nuclei and efferent autonomic/JNK1 pathways.
Imbernon M, Beiroa D, Vázquez MJ, Morgan DA, Veyrat-Durebex C, Porteiro B, Díaz-Arteaga A, Senra A, Busquets S, Velásquez DA, Al-Massadi O, Varela L, Gándara M, López-Soriano FJ, Gallego R, Seoane LM, Argiles JM, López M, Davis RJ, Sabio G, Rohner-Jeanrenaud F, Rahmouni K, Dieguez C, Nogueiras R. Imbernon M, et al. Gastroenterology. 2013 Mar;144(3):636-649.e6. doi: 10.1053/j.gastro.2012.10.051. Epub 2012 Nov 6. Gastroenterology. 2013. PMID: 23142626 Free PMC article.
Endocrine control of energy homeostasis.
Rohner-Jeanrenaud F, Nogueiras R. Rohner-Jeanrenaud F, et al. Mol Cell Endocrinol. 2015 Dec 15;418 Pt 1:1-2. doi: 10.1016/j.mce.2015.11.003. Mol Cell Endocrinol. 2015. PMID: 26573182 No abstract available.
The central melanocortin system directly controls peripheral lipid metabolism.
Nogueiras R, Wiedmer P, Perez-Tilve D, Veyrat-Durebex C, Keogh JM, Sutton GM, Pfluger PT, Castaneda TR, Neschen S, Hofmann SM, Howles PN, Morgan DA, Benoit SC, Szanto I, Schrott B, Schürmann A, Joost HG, Hammond C, Hui DY, Woods SC, Rahmouni K, Butler AA, Farooqi IS, O'Rahilly S, Rohner-Jeanrenaud F, Tschöp MH. Nogueiras R, et al. J Clin Invest. 2007 Nov;117(11):3475-88. doi: 10.1172/JCI31743. J Clin Invest. 2007. PMID: 17885689 Free PMC article.
Central nervous system regulation of adipocyte metabolism.
Nogueiras R, Wilson H, Rohner-Jeanrenaud F, Tschöp MH. Nogueiras R, et al. Regul Pept. 2008 Aug 7;149(1-3):26-31. doi: 10.1016/j.regpep.2007.09.034. Epub 2008 Apr 1. Regul Pept. 2008. PMID: 18453013 Review.
Direct control of peripheral lipid deposition by CNS GLP-1 receptor signaling is mediated by the sympathetic nervous system and blunted in diet-induced obesity.
Nogueiras R, Pérez-Tilve D, Veyrat-Durebex C, Morgan DA, Varela L, Haynes WG, Patterson JT, Disse E, Pfluger PT, López M, Woods SC, DiMarchi R, Diéguez C, Rahmouni K, Rohner-Jeanrenaud F, Tschöp MH. Nogueiras R, et al. J Neurosci. 2009 May 6;29(18):5916-25. doi: 10.1523/JNEUROSCI.5977-08.2009. J Neurosci. 2009. PMID: 19420258 Free PMC article.
Direct control of brown adipose tissue thermogenesis by central nervous system glucagon-like peptide-1 receptor signaling.
Lockie SH, Heppner KM, Chaudhary N, Chabenne JR, Morgan DA, Veyrat-Durebex C, Ananthakrishnan G, Rohner-Jeanrenaud F, Drucker DJ, DiMarchi R, Rahmouni K, Oldfield BJ, Tschöp MH, Perez-Tilve D. Lockie SH, et al. Diabetes. 2012 Nov;61(11):2753-62. doi: 10.2337/db11-1556. Epub 2012 Aug 28. Diabetes. 2012. PMID: 22933116 Free PMC article.
152 results