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HERV-K-specific T cells eliminate diverse HIV-1/2 and SIV primary isolates.
Jones RB, Garrison KE, Mujib S, Mihajlovic V, Aidarus N, Hunter DV, Martin E, John VM, Zhan W, Faruk NF, Gyenes G, Sheppard NC, Priumboom-Brees IM, Goodwin DA, Chen L, Rieger M, Muscat-King S, Loudon PT, Stanley C, Holditch SJ, Wong JC, Clayton K, Duan E, Song H, Xu Y, SenGupta D, Tandon R, Sacha JB, Brockman MA, Benko E, Kovacs C, Nixon DF, Ostrowski MA. Jones RB, et al. Among authors: sacha jb. J Clin Invest. 2012 Dec;122(12):4473-89. doi: 10.1172/JCI64560. Epub 2012 Nov 12. J Clin Invest. 2012. PMID: 23143309 Free PMC article.
Vaccination with cancer- and HIV infection-associated endogenous retrotransposable elements is safe and immunogenic.
Sacha JB, Kim IJ, Chen L, Ullah JH, Goodwin DA, Simmons HA, Schenkman DI, von Pelchrzim F, Gifford RJ, Nimityongskul FA, Newman LP, Wildeboer S, Lappin PB, Hammond D, Castrovinci P, Piaskowski SM, Reed JS, Beheler KA, Tharmanathan T, Zhang N, Muscat-King S, Rieger M, Fernandes C, Rumpel K, Gardner JP 2nd, Gebhard DH, Janies J, Shoieb A, Pierce BG, Trajkovic D, Rakasz E, Rong S, McCluskie M, Christy C, Merson JR, Jones RB, Nixon DF, Ostrowski MA, Loudon PT, Pruimboom-Brees IM, Sheppard NC. Sacha JB, et al. J Immunol. 2012 Aug 1;189(3):1467-79. doi: 10.4049/jimmunol.1200079. Epub 2012 Jun 27. J Immunol. 2012. PMID: 22745376 Free PMC article.
T cells target APOBEC3 proteins in human immunodeficiency virus type 1-infected humans and simian immunodeficiency virus-infected Indian rhesus macaques.
Champiat S, Garrison KE, Raposo RA, Burwitz BJ, Reed J, Tandon R, York VA, Newman LP, Nimityongskul FA, Wilson NA, Almeida RR, Martin JN, Deeks SG, Rosenberg MG, Wiznia AA, Spotts GE, Pilcher CD, Hecht FM, Ostrowski MA, Sacha JB, Nixon DF. Champiat S, et al. Among authors: sacha jb. J Virol. 2013 Jun;87(11):6073-80. doi: 10.1128/JVI.00579-12. Epub 2013 Mar 27. J Virol. 2013. PMID: 23536679 Free PMC article.
Vaccination against endogenous retrotransposable element consensus sequences does not protect rhesus macaques from SIVsmE660 infection and replication.
Sheppard NC, Jones RB, Burwitz BJ, Nimityongskul FA, Newman LP, Buechler MB, Reed JS, Piaskowski SM, Weisgrau KL, Castrovinci PA, Wilson NA, Ostrowski MA, Park B, Nixon DF, Rakasz EG, Sacha JB. Sheppard NC, et al. Among authors: sacha jb. PLoS One. 2014 Mar 20;9(3):e92012. doi: 10.1371/journal.pone.0092012. eCollection 2014. PLoS One. 2014. PMID: 24651676 Free PMC article.
Expansion of dysfunctional Tim-3-expressing effector memory CD8+ T cells during simian immunodeficiency virus infection in rhesus macaques.
Fujita T, Burwitz BJ, Chew GM, Reed JS, Pathak R, Seger E, Clayton KL, Rini JM, Ostrowski MA, Ishii N, Kuroda MJ, Hansen SG, Sacha JB, Ndhlovu LC. Fujita T, et al. Among authors: sacha jb. J Immunol. 2014 Dec 1;193(11):5576-83. doi: 10.4049/jimmunol.1400961. Epub 2014 Oct 27. J Immunol. 2014. PMID: 25348621 Free PMC article.
TIGIT Marks Exhausted T Cells, Correlates with Disease Progression, and Serves as a Target for Immune Restoration in HIV and SIV Infection.
Chew GM, Fujita T, Webb GM, Burwitz BJ, Wu HL, Reed JS, Hammond KB, Clayton KL, Ishii N, Abdel-Mohsen M, Liegler T, Mitchell BI, Hecht FM, Ostrowski M, Shikuma CM, Hansen SG, Maurer M, Korman AJ, Deeks SG, Sacha JB, Ndhlovu LC. Chew GM, et al. Among authors: sacha jb. PLoS Pathog. 2016 Jan 7;12(1):e1005349. doi: 10.1371/journal.ppat.1005349. eCollection 2016 Jan. PLoS Pathog. 2016. PMID: 26741490 Free PMC article.
Anti-HERV-K (HML-2) capsid antibody responses in HIV elite controllers.
de Mulder M, SenGupta D, Deeks SG, Martin JN, Pilcher CD, Hecht FM, Sacha JB, Nixon DF, Michaud HA. de Mulder M, et al. Among authors: sacha jb. Retrovirology. 2017 Aug 22;14(1):41. doi: 10.1186/s12977-017-0365-2. Retrovirology. 2017. PMID: 28830571 Free PMC article.
The human IL-15 superagonist ALT-803 directs SIV-specific CD8+ T cells into B-cell follicles.
Webb GM, Li S, Mwakalundwa G, Folkvord JM, Greene JM, Reed JS, Stanton JJ, Legasse AW, Hobbs T, Martin LD, Park BS, Whitney JB, Jeng EK, Wong HC, Nixon DF, Jones RB, Connick E, Skinner PJ, Sacha JB. Webb GM, et al. Among authors: sacha jb. Blood Adv. 2018 Jan 23;2(2):76-84. doi: 10.1182/bloodadvances.2017012971. Blood Adv. 2018. PMID: 29365313 Free PMC article.
101 results