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Page 1
Aberrant overexpression of IL-15 initiates large granular lymphocyte leukemia through chromosomal instability and DNA hypermethylation.
Mishra A, Liu S, Sams GH, Curphey DP, Santhanam R, Rush LJ, Schaefer D, Falkenberg LG, Sullivan L, Jaroncyk L, Yang X, Fisk H, Wu LC, Hickey C, Chandler JC, Wu YZ, Heerema NA, Chan KK, Perrotti D, Zhang J, Porcu P, Racke FK, Garzon R, Lee RJ, Marcucci G, Caligiuri MA. Mishra A, et al. Among authors: chandler jc. Cancer Cell. 2012 Nov 13;22(5):645-55. doi: 10.1016/j.ccr.2012.09.009. Cancer Cell. 2012. PMID: 23153537 Free PMC article.
miR-328 functions as an RNA decoy to modulate hnRNP E2 regulation of mRNA translation in leukemic blasts.
Eiring AM, Harb JG, Neviani P, Garton C, Oaks JJ, Spizzo R, Liu S, Schwind S, Santhanam R, Hickey CJ, Becker H, Chandler JC, Andino R, Cortes J, Hokland P, Huettner CS, Bhatia R, Roy DC, Liebhaber SA, Caligiuri MA, Marcucci G, Garzon R, Croce CM, Calin GA, Perrotti D. Eiring AM, et al. Among authors: chandler jc. Cell. 2010 Mar 5;140(5):652-65. doi: 10.1016/j.cell.2010.01.007. Cell. 2010. PMID: 20211135 Free PMC article.
Dose escalation of lenalidomide in relapsed or refractory acute leukemias.
Blum W, Klisovic RB, Becker H, Yang X, Rozewski DM, Phelps MA, Garzon R, Walker A, Chandler JC, Whitman SP, Curfman J, Liu S, Schaaf L, Mickle J, Kefauver C, Devine SM, Grever MR, Marcucci G, Byrd JC. Blum W, et al. Among authors: chandler jc. J Clin Oncol. 2010 Nov 20;28(33):4919-25. doi: 10.1200/JCO.2010.30.3339. Epub 2010 Oct 18. J Clin Oncol. 2010. PMID: 20956622 Free PMC article. Clinical Trial.
Single-cell transcriptomics identifies aberrant glomerular angiogenic signalling in the early stages of WT1 kidney disease.
Chandler JC, Jafree DJ, Malik S, Pomeranz G, Ball M, Kolatsi-Joannou M, Piapi A, Mason WJ, Benest AV, Bates DO, Letunovska A, Al-Saadi R, Rabant M, Boyer O, Pritchard-Jones K, Winyard PJ, Mason AS, Woolf AS, Waters AM, Long DA. Chandler JC, et al. J Pathol. 2024 Oct;264(2):212-227. doi: 10.1002/path.6339. Epub 2024 Aug 23. J Pathol. 2024. PMID: 39177649
Accelerated evolution of SARS-CoV-2 in free-ranging white-tailed deer.
McBride DS, Garushyants SK, Franks J, Magee AF, Overend SH, Huey D, Williams AM, Faith SA, Kandeil A, Trifkovic S, Miller L, Jeevan T, Patel A, Nolting JM, Tonkovich MJ, Genders JT, Montoney AJ, Kasnyik K, Linder TJ, Bevins SN, Lenoch JB, Chandler JC, DeLiberto TJ, Koonin EV, Suchard MA, Lemey P, Webby RJ, Nelson MI, Bowman AS. McBride DS, et al. Among authors: chandler jc. Nat Commun. 2023 Aug 28;14(1):5105. doi: 10.1038/s41467-023-40706-y. Nat Commun. 2023. PMID: 37640694 Free PMC article.
Phase Ib study of combinations of avadomide (CC-122), CC-223, CC-292, and rituximab in patients with relapsed/refractory diffuse large B-cell lymphoma.
Ribrag V, Chavez JC, Boccomini C, Kaplan J, Chandler JC, Santoro A, Corradini P, Flinn IW, Advani R, Cassier PA, Sangha R, Kenkre VP, Isufi I, Uttamsingh S, Hagner PR, Gandhi AK, Shen F, Michelliza S, Haeske H, Hege K, Pourdehnad M, Kuruvilla J. Ribrag V, et al. Among authors: chandler jc. EJHaem. 2022 Jan 14;3(1):139-153. doi: 10.1002/jha2.375. eCollection 2022 Feb. EJHaem. 2022. PMID: 35846221 Free PMC article.
Phase 1 Study Evaluating Pharmacokinetics and Tolerability of Ofatumumab Combined With Bendamustine in Patients With Indolent B-Cell Non-Hodgkin's Lymphoma.
Forero-Torres A, Chandler JC, Iyer SP, Kanate AS, Quinlan M, Hoever P, Izquierdo M, Davis J, Madan S. Forero-Torres A, et al. Among authors: chandler jc. Clin Pharmacol Drug Dev. 2022 Sep;11(9):1099-1109. doi: 10.1002/cpdd.1133. Epub 2022 Jul 12. Clin Pharmacol Drug Dev. 2022. PMID: 35819310 Clinical Trial.
SARS-CoV-2 exposure in wild white-tailed deer (Odocoileus virginianus).
Chandler JC, Bevins SN, Ellis JW, Linder TJ, Tell RM, Jenkins-Moore M, Root JJ, Lenoch JB, Robbe-Austerman S, DeLiberto TJ, Gidlewski T, Kim Torchetti M, Shriner SA. Chandler JC, et al. Proc Natl Acad Sci U S A. 2021 Nov 23;118(47):e2114828118. doi: 10.1073/pnas.2114828118. Proc Natl Acad Sci U S A. 2021. PMID: 34732584 Free PMC article.
76 results