Lehrach H - Search Results

1

Pyruvate kinase is a dosage-dependent regulator of cellular amino acid homeostasis.

Bluemlein K, Glückmann M, Grüning NM, Feichtinger R, Krüger A, Wamelink M, Lehrach H, Tate S, Neureiter D, Kofler B, Ralser M. Bluemlein K, et al. Among authors: lehrach h. Oncotarget. 2012 Nov;3(11):1356-69. doi: 10.18632/oncotarget.730. Oncotarget. 2012. PMID: 23154538 Free PMC article.

2

No evidence for a shift in pyruvate kinase PKM1 to PKM2 expression during tumorigenesis.

Bluemlein K, Grüning NM, Feichtinger RG, Lehrach H, Kofler B, Ralser M. Bluemlein K, et al. Among authors: lehrach h. Oncotarget. 2011 May;2(5):393-400. doi: 10.18632/oncotarget.278. Oncotarget. 2011. PMID: 21789790 Free PMC article.

3

Pyruvate kinase triggers a metabolic feedback loop that controls redox metabolism in respiring cells.

Grüning NM, Rinnerthaler M, Bluemlein K, Mülleder M, Wamelink MM, Lehrach H, Jakobs C, Breitenbach M, Ralser M. Grüning NM, et al. Among authors: lehrach h. Cell Metab. 2011 Sep 7;14(3):415-27. doi: 10.1016/j.cmet.2011.06.017. Cell Metab. 2011. PMID: 21907146 Free PMC article.

4

Regulatory crosstalk of the metabolic network.

Grüning NM, Lehrach H, Ralser M. Grüning NM, et al. Among authors: lehrach h. Trends Biochem Sci. 2010 Apr;35(4):220-7. doi: 10.1016/j.tibs.2009.12.001. Epub 2010 Jan 7. Trends Biochem Sci. 2010. PMID: 20060301 Review.

5

The pentose phosphate pathway is a metabolic redox sensor and regulates transcription during the antioxidant response.

Krüger A, Grüning NM, Wamelink MM, Kerick M, Kirpy A, Parkhomchuk D, Bluemlein K, Schweiger MR, Soldatov A, Lehrach H, Jakobs C, Ralser M. Krüger A, et al. Among authors: lehrach h. Antioxid Redox Signal. 2011 Jul 15;15(2):311-24. doi: 10.1089/ars.2010.3797. Epub 2011 May 19. Antioxid Redox Signal. 2011. PMID: 21348809

6

Low catalytic activity is insufficient to induce disease pathology in triosephosphate isomerase deficiency.

Segal J, Mülleder M, Krüger A, Adler T, Scholze-Wittler M, Becker L, Calzada-Wack J, Garrett L, Hölter SM, Rathkolb B, Rozman J, Racz I, Fischer R, Busch DH, Neff F, Klingenspor M, Klopstock T, Grüning NM, Michel S, Lukaszewska-McGreal B, Voigt I, Hartmann L, Timmermann B, Lehrach H, Wolf E, Wurst W, Gailus-Durner V, Fuchs H, H de Angelis M, Schrewe H, Yuneva M, Ralser M. Segal J, et al. Among authors: lehrach h, h de angelis m. J Inherit Metab Dis. 2019 Sep;42(5):839-849. doi: 10.1002/jimd.12105. Epub 2019 Jun 11. J Inherit Metab Dis. 2019. PMID: 31111503 Free PMC article.

7

Interfering with glycolysis causes Sir2-dependent hyper-recombination of Saccharomyces cerevisiae plasmids.

Ralser M, Zeidler U, Lehrach H. Ralser M, et al. Among authors: lehrach h. PLoS One. 2009;4(4):e5376. doi: 10.1371/journal.pone.0005376. Epub 2009 Apr 24. PLoS One. 2009. PMID: 19390637 Free PMC article.

8

The difference between rare and exceptionally rare: molecular characterization of ribose 5-phosphate isomerase deficiency.

Wamelink MM, Grüning NM, Jansen EE, Bluemlein K, Lehrach H, Jakobs C, Ralser M. Wamelink MM, et al. Among authors: lehrach h. J Mol Med (Berl). 2010 Sep;88(9):931-9. doi: 10.1007/s00109-010-0634-1. Epub 2010 May 25. J Mol Med (Berl). 2010. PMID: 20499043

9

The Saccharomyces cerevisiae W303-K6001 cross-platform genome sequence: insights into ancestry and physiology of a laboratory mutt.

Ralser M, Kuhl H, Ralser M, Werber M, Lehrach H, Breitenbach M, Timmermann B. Ralser M, et al. Among authors: lehrach h. Open Biol. 2012 Aug;2(8):120093. doi: 10.1098/rsob.120093. Open Biol. 2012. PMID: 22977733 Free PMC article.

10

Human induced pluripotent stem cells harbor homoplasmic and heteroplasmic mitochondrial DNA mutations while maintaining human embryonic stem cell-like metabolic reprogramming.

Prigione A, Lichtner B, Kuhl H, Struys EA, Wamelink M, Lehrach H, Ralser M, Timmermann B, Adjaye J. Prigione A, et al. Among authors: lehrach h. Stem Cells. 2011 Sep;29(9):1338-48. doi: 10.1002/stem.683. Stem Cells. 2011. PMID: 21732474

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