Koren I - Search Results

1

Cell biology. Promoting tumorigenesis by suppressing autophagy.

Koren I, Kimchi A. Koren I, et al. Science. 2012 Nov 16;338(6109):889-90. doi: 10.1126/science.1230577. Science. 2012. PMID: 23161981 No abstract available.

2

Molecular basis for C-degron recognition by CRL2^APPBP2 ubiquitin ligase.

Zhao S, Olmayev-Yaakobov D, Ru W, Li S, Chen X, Zhang J, Yao X, Koren I, Zhang K, Xu C. Zhao S, et al. Among authors: koren i. Proc Natl Acad Sci U S A. 2023 Oct 24;120(43):e2308870120. doi: 10.1073/pnas.2308870120. Epub 2023 Oct 16. Proc Natl Acad Sci U S A. 2023. PMID: 37844242 Free PMC article.

3

DAP-kinase-mediated phosphorylation on the BH3 domain of beclin 1 promotes dissociation of beclin 1 from Bcl-XL and induction of autophagy.

Zalckvar E, Berissi H, Mizrachy L, Idelchuk Y, Koren I, Eisenstein M, Sabanay H, Pinkas-Kramarski R, Kimchi A. Zalckvar E, et al. Among authors: koren i. EMBO Rep. 2009 Mar;10(3):285-92. doi: 10.1038/embor.2008.246. Epub 2009 Jan 30. EMBO Rep. 2009. PMID: 19180116 Free PMC article.

4

DAP1, a novel substrate of mTOR, negatively regulates autophagy.

Koren I, Reem E, Kimchi A. Koren I, et al. Curr Biol. 2010 Jun 22;20(12):1093-8. doi: 10.1016/j.cub.2010.04.041. Epub 2010 May 27. Curr Biol. 2010. PMID: 20537536 Free article.

5

Autophagy gets a brake: DAP1, a novel mTOR substrate, is activated to suppress the autophagic process.

Koren I, Reem E, Kimchi A. Koren I, et al. Autophagy. 2010 Nov;6(8):1179-80. doi: 10.4161/auto.6.8.13338. Autophagy. 2010. PMID: 20818178 Free PMC article.

6

A glycine-specific N-degron pathway mediates the quality control of protein N-myristoylation.

Timms RT, Zhang Z, Rhee DY, Harper JW, Koren I, Elledge SJ. Timms RT, et al. Among authors: koren i. Science. 2019 Jul 5;365(6448):eaaw4912. doi: 10.1126/science.aaw4912. Science. 2019. PMID: 31273098 Free PMC article.

7

Quantitative Proteomic Atlas of Ubiquitination and Acetylation in the DNA Damage Response.

Elia AE, Boardman AP, Wang DC, Huttlin EL, Everley RA, Dephoure N, Zhou C, Koren I, Gygi SP, Elledge SJ. Elia AE, et al. Among authors: koren i. Mol Cell. 2015 Sep 3;59(5):867-81. doi: 10.1016/j.molcel.2015.05.006. Epub 2015 Jun 4. Mol Cell. 2015. PMID: 26051181 Free PMC article.

8

The Eukaryotic Proteome Is Shaped by E3 Ubiquitin Ligases Targeting C-Terminal Degrons.

Koren I, Timms RT, Kula T, Xu Q, Li MZ, Elledge SJ. Koren I, et al. Cell. 2018 Jun 14;173(7):1622-1635.e14. doi: 10.1016/j.cell.2018.04.028. Epub 2018 May 17. Cell. 2018. PMID: 29779948 Free PMC article.

9

Tying up loose ends: the N-degron and C-degron pathways of protein degradation.

Timms RT, Koren I. Timms RT, et al. Among authors: koren i. Biochem Soc Trans. 2020 Aug 28;48(4):1557-1567. doi: 10.1042/BST20191094. Biochem Soc Trans. 2020. PMID: 32627813 Free PMC article. Review.

10

Molecular basis for arginine C-terminal degron recognition by Cul2^FEM1 E3 ligase.

Chen X, Liao S, Makaros Y, Guo Q, Zhu Z, Krizelman R, Dahan K, Tu X, Yao X, Koren I, Xu C. Chen X, et al. Among authors: koren i. Nat Chem Biol. 2021 Mar;17(3):254-262. doi: 10.1038/s41589-020-00704-3. Epub 2021 Jan 4. Nat Chem Biol. 2021. PMID: 33398168

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