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Page 1
Interactions between epigenetics and metabolism in cancers.
Yun J, Johnson JL, Hanigan CL, Locasale JW. Yun J, et al. Among authors: locasale jw. Front Oncol. 2012 Nov 15;2:163. doi: 10.3389/fonc.2012.00163. eCollection 2012. Front Oncol. 2012. PMID: 23162793 Free PMC article.
Autophagy-dependent metabolic reprogramming sensitizes TSC2-deficient cells to the antimetabolite 6-aminonicotinamide.
Parkhitko AA, Priolo C, Coloff JL, Yun J, Wu JJ, Mizumura K, Xu W, Malinowska IA, Yu J, Kwiatkowski DJ, Locasale JW, Asara JM, Choi AM, Finkel T, Henske EP. Parkhitko AA, et al. Among authors: locasale jw. Mol Cancer Res. 2014 Jan;12(1):48-57. doi: 10.1158/1541-7786.MCR-13-0258-T. Epub 2013 Dec 2. Mol Cancer Res. 2014. PMID: 24296756 Free PMC article.
Altered metabolism in cancer.
Locasale JW, Cantley LC. Locasale JW, et al. BMC Biol. 2010 Jun 25;8:88. doi: 10.1186/1741-7007-8-88. BMC Biol. 2010. PMID: 20598111 Free PMC article.
PHGDH amplification and altered glucose metabolism in human melanoma.
Mullarky E, Mattaini KR, Vander Heiden MG, Cantley LC, Locasale JW. Mullarky E, et al. Among authors: locasale jw. Pigment Cell Melanoma Res. 2011 Dec;24(6):1112-5. doi: 10.1111/j.1755-148X.2011.00919.x. Epub 2011 Oct 28. Pigment Cell Melanoma Res. 2011. PMID: 21981974 Review.
Epigenetics and cancer metabolism.
Johnson C, Warmoes MO, Shen X, Locasale JW. Johnson C, et al. Among authors: locasale jw. Cancer Lett. 2015 Jan 28;356(2 Pt A):309-14. doi: 10.1016/j.canlet.2013.09.043. Epub 2013 Oct 11. Cancer Lett. 2015. PMID: 24125862 Free PMC article. Review.
Dysregulated metabolism contributes to oncogenesis.
Hirschey MD, DeBerardinis RJ, Diehl AME, Drew JE, Frezza C, Green MF, Jones LW, Ko YH, Le A, Lea MA, Locasale JW, Longo VD, Lyssiotis CA, McDonnell E, Mehrmohamadi M, Michelotti G, Muralidhar V, Murphy MP, Pedersen PL, Poore B, Raffaghello L, Rathmell JC, Sivanand S, Vander Heiden MG, Wellen KE; Target Validation Team. Hirschey MD, et al. Among authors: locasale jw. Semin Cancer Biol. 2015 Dec;35 Suppl:S129-S150. doi: 10.1016/j.semcancer.2015.10.002. Epub 2015 Oct 8. Semin Cancer Biol. 2015. PMID: 26454069 Free PMC article. Review.
Metabolic interactions with cancer epigenetics.
Gao X, Reid MA, Kong M, Locasale JW. Gao X, et al. Among authors: locasale jw. Mol Aspects Med. 2017 Apr;54:50-57. doi: 10.1016/j.mam.2016.09.001. Epub 2016 Sep 9. Mol Aspects Med. 2017. PMID: 27620316 Free PMC article. Review.
Metabolic decisions in development and disease-a Keystone Symposia report.
Cable J, Pourquié O, Wellen KE, Finley LWS, Aulehla A, Gould AP, Teleman A, Tu WB, Garrett WS, Miguel-Aliaga I, Perrimon N, Hooper LV, Walhout AJM, Wei W, Alexandrov T, Erez A, Ralser M, Rabinowitz JD, Hemalatha A, Gutiérrez-Pérez P, Chandel NS, Rutter J, Locasale JW, Landoni JC, Christofk H. Cable J, et al. Among authors: locasale jw. Ann N Y Acad Sci. 2021 Dec;1506(1):55-73. doi: 10.1111/nyas.14678. Epub 2021 Aug 19. Ann N Y Acad Sci. 2021. PMID: 34414571 Review.
Phosphoglycerate dehydrogenase diverts glycolytic flux and contributes to oncogenesis.
Locasale JW, Grassian AR, Melman T, Lyssiotis CA, Mattaini KR, Bass AJ, Heffron G, Metallo CM, Muranen T, Sharfi H, Sasaki AT, Anastasiou D, Mullarky E, Vokes NI, Sasaki M, Beroukhim R, Stephanopoulos G, Ligon AH, Meyerson M, Richardson AL, Chin L, Wagner G, Asara JM, Brugge JS, Cantley LC, Vander Heiden MG. Locasale JW, et al. Nat Genet. 2011 Jul 31;43(9):869-74. doi: 10.1038/ng.890. Nat Genet. 2011. PMID: 21804546 Free PMC article.
221 results