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CD161(+)CD4(+) T cells are enriched in the liver during chronic hepatitis and associated with co-secretion of IL-22 and IFN-γ.
Kang YH, Seigel B, Bengsch B, Fleming VM, Billerbeck E, Simmons R, Walker L, Willberg CB, Barnes EJ, Bhagwanani A, Oo YH, Blum HE, Adams DH, Thimme R, Klenerman P. Kang YH, et al. Among authors: fleming vm. Front Immunol. 2012 Nov 20;3:346. doi: 10.3389/fimmu.2012.00346. eCollection 2012. Front Immunol. 2012. PMID: 23181064 Free PMC article.
CD161-expressing human T cells.
Fergusson JR, Fleming VM, Klenerman P. Fergusson JR, et al. Among authors: fleming vm. Front Immunol. 2011 Aug 30;2:36. doi: 10.3389/fimmu.2011.00036. eCollection 2011. Front Immunol. 2011. PMID: 22566826 Free PMC article.
Human MAIT and CD8αα cells develop from a pool of type-17 precommitted CD8+ T cells.
Walker LJ, Kang YH, Smith MO, Tharmalingham H, Ramamurthy N, Fleming VM, Sahgal N, Leslie A, Oo Y, Geremia A, Scriba TJ, Hanekom WA, Lauer GM, Lantz O, Adams DH, Powrie F, Barnes E, Klenerman P. Walker LJ, et al. Among authors: fleming vm. Blood. 2012 Jan 12;119(2):422-33. doi: 10.1182/blood-2011-05-353789. Epub 2011 Nov 15. Blood. 2012. PMID: 22086415 Free PMC article.
What are the prospects for controlling hepatitis C?
Klenerman P, Fleming V, Barnes E. Klenerman P, et al. PLoS Med. 2009 Jun 16;6(6):e1000096. doi: 10.1371/journal.pmed.1000096. Epub 2009 Jun 16. PLoS Med. 2009. PMID: 19529757 Free PMC article. No abstract available.
Analysis of CD161 expression on human CD8+ T cells defines a distinct functional subset with tissue-homing properties.
Billerbeck E, Kang YH, Walker L, Lockstone H, Grafmueller S, Fleming V, Flint J, Willberg CB, Bengsch B, Seigel B, Ramamurthy N, Zitzmann N, Barnes EJ, Thevanayagam J, Bhagwanani A, Leslie A, Oo YH, Kollnberger S, Bowness P, Drognitz O, Adams DH, Blum HE, Thimme R, Klenerman P. Billerbeck E, et al. Proc Natl Acad Sci U S A. 2010 Feb 16;107(7):3006-11. doi: 10.1073/pnas.0914839107. Epub 2010 Jan 28. Proc Natl Acad Sci U S A. 2010. PMID: 20133607 Free PMC article.
CD161 defines a transcriptional and functional phenotype across distinct human T cell lineages.
Fergusson JR, Smith KE, Fleming VM, Rajoriya N, Newell EW, Simmons R, Marchi E, Björkander S, Kang YH, Swadling L, Kurioka A, Sahgal N, Lockstone H, Baban D, Freeman GJ, Sverremark-Ekström E, Davis MM, Davenport MP, Venturi V, Ussher JE, Willberg CB, Klenerman P. Fergusson JR, et al. Among authors: fleming vm. Cell Rep. 2014 Nov 6;9(3):1075-88. doi: 10.1016/j.celrep.2014.09.045. Epub 2014 Oct 23. Cell Rep. 2014. PMID: 25437561 Free PMC article.
Dynamic coinfection with multiple viral subtypes in acute hepatitis C.
Smith JA, Aberle JH, Fleming VM, Ferenci P, Thomson EC, Karayiannis P, McLean AR, Holzmann H, Klenerman P. Smith JA, et al. Among authors: fleming vm. J Infect Dis. 2010 Dec 15;202(12):1770-9. doi: 10.1086/657317. Epub 2010 Nov 10. J Infect Dis. 2010. PMID: 21067369 Free PMC article.
Hepatitis C virus (HCV) sequence variation induces an HCV-specific T-cell phenotype analogous to spontaneous resolution.
Kasprowicz V, Kang YH, Lucas M, Schulze zur Wiesch J, Kuntzen T, Fleming V, Nolan BE, Longworth S, Berical A, Bengsch B, Thimme R, Lewis-Ximenez L, Allen TM, Kim AY, Klenerman P, Lauer GM. Kasprowicz V, et al. J Virol. 2010 Feb;84(3):1656-63. doi: 10.1128/JVI.01499-09. Epub 2009 Nov 11. J Virol. 2010. PMID: 19906915 Free PMC article.
47 results