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Preclinical characterization of GS-9669, a thumb site II inhibitor of the hepatitis C virus NS5B polymerase.
Fenaux M, Eng S, Leavitt SA, Lee YJ, Mabery EM, Tian Y, Byun D, Canales E, Clarke MO, Doerffler E, Lazerwith SE, Lew W, Liu Q, Mertzman M, Morganelli P, Xu L, Ye H, Zhang J, Matles M, Murray BP, Mwangi J, Zhang J, Hashash A, Krawczyk SH, Bidgood AM, Appleby TC, Watkins WJ. Fenaux M, et al. Among authors: eng s. Antimicrob Agents Chemother. 2013 Feb;57(2):804-10. doi: 10.1128/AAC.02052-12. Epub 2012 Nov 26. Antimicrob Agents Chemother. 2013. PMID: 23183437 Free PMC article. Clinical Trial.
Inhibition of hepatitis C virus replication by GS-6620, a potent C-nucleoside monophosphate prodrug.
Feng JY, Cheng G, Perry J, Barauskas O, Xu Y, Fenaux M, Eng S, Tirunagari N, Peng B, Yu M, Tian Y, Lee YJ, Stepan G, Lagpacan LL, Jin D, Hung M, Ku KS, Han B, Kitrinos K, Perron M, Birkus G, Wong KA, Zhong W, Kim CU, Carey A, Cho A, Ray AS. Feng JY, et al. Among authors: eng s. Antimicrob Agents Chemother. 2014;58(4):1930-42. doi: 10.1128/AAC.02351-13. Epub 2014 Jan 13. Antimicrob Agents Chemother. 2014. PMID: 24419349 Free PMC article.
Nucleotide Prodrug Containing a Nonproteinogenic Amino Acid To Improve Oral Delivery of a Hepatitis C Virus Treatment.
Feng JY, Wang T, Park Y, Babusis D, Birkus G, Xu Y, Voitenleitner C, Fenaux M, Yang H, Eng S, Tirunagari N, Kirschberg T, Cho A, Ray AS. Feng JY, et al. Among authors: eng s. Antimicrob Agents Chemother. 2018 Jul 27;62(8):e00620-18. doi: 10.1128/AAC.00620-18. Print 2018 Aug. Antimicrob Agents Chemother. 2018. PMID: 29866875 Free PMC article.
Selective depletion of HBV-infected hepatocytes by class A capsid assembly modulators requires high levels of intrahepatic HBV core protein.
Kornyeyev D, Song Z, Eng S, Soulette C, Ramirez R, Tang J, Yue Q, Subramanian R, Zaboli S, Moon C, Tam J, Brodbeck J, Aggarwal A, Diehl L, Fletcher SP, Hyrina A, Holdorf MM, Burdette D. Kornyeyev D, et al. Among authors: eng s. Antimicrob Agents Chemother. 2024 Jul 9;68(7):e0042024. doi: 10.1128/aac.00420-24. Epub 2024 May 23. Antimicrob Agents Chemother. 2024. PMID: 38780261 Free PMC article.
Tumor upstaging in invasive melanoma is associated with changes in clinical management and worse prognosis.
Rosenthal A, Kim JY, Juhasz MLW, Conde G, Chen C, Eng S, Carrasco Mendoza CA, Chang CT, Ticknor I, Doan L, Schwarzmann KB, Garzione S, Li Y, Islas ZA, Gharavi NM, Man JR. Rosenthal A, et al. Among authors: eng s. J Am Acad Dermatol. 2024 Nov 22:S0190-9622(24)03233-X. doi: 10.1016/j.jaad.2024.11.028. Online ahead of print. J Am Acad Dermatol. 2024. PMID: 39579989
A phase III study to evaluate the long-term safety and efficacy of fasinumab in patients with pain due to osteoarthritis of the knee or hip.
DiMartino SJ, Mei J, Schnitzer TJ, Gao H, Eng S, Winslow C, Ho T, Turner KC, Hassan HE, Patel Y, Davis JD, Trinh N, Manley A, Manvelian G, Fetell M, Braunstein N, Geba GP, Dakin P. DiMartino SJ, et al. Among authors: eng s. Osteoarthr Cartil Open. 2024 Oct 22;6(4):100533. doi: 10.1016/j.ocarto.2024.100533. eCollection 2024 Dec. Osteoarthr Cartil Open. 2024. PMID: 39554479 Free PMC article.
A digital, decentralized trial of exercise therapy in patients with cancer.
Underwood WP, Michalski MG, Lee CP, Fickera GA, Chun SS, Eng SE, Liu LY, Tsai BL, Moskowitz CS, Lavery JA, Van Zee KJ, Gardner GJ, Mueller JJ, Dang CT, Ehdaie B, Laudone VP, Eastham JA, Scott JM, Boutros PC, Jones LW. Underwood WP, et al. Among authors: eng se. NPJ Digit Med. 2024 Oct 28;7(1):304. doi: 10.1038/s41746-024-01288-1. NPJ Digit Med. 2024. PMID: 39468290 Free PMC article.
263 results