Krawczyk SH - Search Results

1

Preclinical characterization of GS-9669, a thumb site II inhibitor of the hepatitis C virus NS5B polymerase.

Fenaux M, Eng S, Leavitt SA, Lee YJ, Mabery EM, Tian Y, Byun D, Canales E, Clarke MO, Doerffler E, Lazerwith SE, Lew W, Liu Q, Mertzman M, Morganelli P, Xu L, Ye H, Zhang J, Matles M, Murray BP, Mwangi J, Zhang J, Hashash A, Krawczyk SH, Bidgood AM, Appleby TC, Watkins WJ. Fenaux M, et al. Among authors: krawczyk sh. Antimicrob Agents Chemother. 2013 Feb;57(2):804-10. doi: 10.1128/AAC.02052-12. Epub 2012 Nov 26. Antimicrob Agents Chemother. 2013. PMID: 23183437 Free PMC article. Clinical Trial.

2

Preclinical characterization of the novel hepatitis C virus NS3 protease inhibitor GS-9451.

Yang H, Robinson M, Corsa AC, Peng B, Cheng G, Tian Y, Wang Y, Pakdaman R, Shen M, Qi X, Mo H, Tay C, Krawczyk S, Sheng XC, Kim CU, Yang C, Delaney WE 4th. Yang H, et al. Antimicrob Agents Chemother. 2014;58(2):647-53. doi: 10.1128/AAC.00487-13. Epub 2013 Aug 12. Antimicrob Agents Chemother. 2014. PMID: 23939899 Free PMC article.

3

Small molecules VP-14637 and JNJ-2408068 inhibit respiratory syncytial virus fusion by similar mechanisms.

Douglas JL, Panis ML, Ho E, Lin KY, Krawczyk SH, Grant DM, Cai R, Swaminathan S, Chen X, Cihlar T. Douglas JL, et al. Among authors: krawczyk sh. Antimicrob Agents Chemother. 2005 Jun;49(6):2460-6. doi: 10.1128/AAC.49.6.2460-2466.2005. Antimicrob Agents Chemother. 2005. PMID: 15917547 Free PMC article.

4

Inhibition of respiratory syncytial virus fusion by the small molecule VP-14637 via specific interactions with F protein.

Douglas JL, Panis ML, Ho E, Lin KY, Krawczyk SH, Grant DM, Cai R, Swaminathan S, Cihlar T. Douglas JL, et al. Among authors: krawczyk sh. J Virol. 2003 May;77(9):5054-64. doi: 10.1128/jvi.77.9.5054-5064.2003. J Virol. 2003. PMID: 12692208 Free PMC article.

5

Pyrrolo[2,3-d]pyrimidine nucleosides as inhibitors of human cytomegalovirus.

Turk SR, Shipman C Jr, Nassiri R, Genzlinger G, Krawczyk SH, Townsend LB, Drach JC. Turk SR, et al. Among authors: krawczyk sh. Antimicrob Agents Chemother. 1987 Apr;31(4):544-50. doi: 10.1128/AAC.31.4.544. Antimicrob Agents Chemother. 1987. PMID: 3037998 Free PMC article.

6

Antagonism of the cytotoxic but not antiviral effects of ara-sangivamycin by adenosine.

Birch GM, Krawczyk SH, Townsend LB, Drach JC. Birch GM, et al. Among authors: krawczyk sh. Antimicrob Agents Chemother. 1989 Sep;33(9):1606-8. doi: 10.1128/AAC.33.9.1606. Antimicrob Agents Chemother. 1989. PMID: 2554803 Free PMC article.

7

New series of potent, orally bioavailable, non-peptidic cyclic sulfones as HIV-1 protease inhibitors.

Kim CU, McGee LR, Krawczyk SH, Harwood E, Harada Y, Swaminathan S, Bischofberger N, Chen MS, Cherrington JM, Xiong SF, Griffin L, Cundy KC, Lee A, Yu B, Gulnik S, Erickson JW. Kim CU, et al. Among authors: krawczyk sh. J Med Chem. 1996 Aug 30;39(18):3431-4. doi: 10.1021/jm960340o. J Med Chem. 1996. PMID: 8784440 No abstract available.

8

N2- and C8-substituted oligodeoxynucleotides with enhanced thrombin inhibitory activity in vitro and in vivo.

He GX, Krawczyk SH, Swaminathan S, Shea RG, Dougherty JP, Terhorst T, Law VS, Griffin LC, Coutré S, Bischofberger N. He GX, et al. Among authors: krawczyk sh. J Med Chem. 1998 Jun 18;41(13):2234-42. doi: 10.1021/jm970434d. J Med Chem. 1998. PMID: 9632356

9

Arabinofuranosylpyrrolo[2,3-d]pyrimidines as potential agents for human cytomegalovirus infections.

Krawczyk SH, Bernier-Rodriguez M, Nassiri MR, Kern ER, Wotring LL, Drach JC, Townsend LB. Krawczyk SH, et al. J Med Chem. 1990 Dec;33(12):3160-9. doi: 10.1021/jm00174a011. J Med Chem. 1990. PMID: 2175356

10

Synthesis and antiproliferative and antiviral activity of 2'-deoxy-2'-fluoroarabinofuranosyl analogs of the nucleoside antibiotics toyocamycin and sangivamycin.

Krawczyk SH, Nassiri MR, Kucera LS, Kern ER, Ptak RG, Wotring LL, Drach JC, Townsend LB. Krawczyk SH, et al. J Med Chem. 1995 Sep 29;38(20):4106-14. doi: 10.1021/jm00020a026. J Med Chem. 1995. PMID: 7562946

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