Alkema W - Search Results

1

Assessing the metabolic effects of prednisolone in healthy volunteers using urine metabolic profiling.

Ellero-Simatos S, Szymańska E, Rullmann T, Dokter WH, Ramaker R, Berger R, van Iersel TM, Smilde AK, Hankemeier T, Alkema W. Ellero-Simatos S, et al. Among authors: alkema w. Genome Med. 2012 Nov 30;4(11):94. doi: 10.1186/gm395. eCollection 2012. Genome Med. 2012. PMID: 23199229 Free PMC article.

2

Prednisolone-induced differential gene expression in mouse liver carrying wild type or a dimerization-defective glucocorticoid receptor.

Frijters R, Fleuren W, Toonen EJ, Tuckermann JP, Reichardt HM, van der Maaden H, van Elsas A, van Lierop MJ, Dokter W, de Vlieg J, Alkema W. Frijters R, et al. Among authors: alkema w. BMC Genomics. 2010 Jun 5;11:359. doi: 10.1186/1471-2164-11-359. BMC Genomics. 2010. PMID: 20525385 Free PMC article.

3

Prednisolone-induced changes in gene-expression profiles in healthy volunteers.

Toonen EJ, Fleuren WW, Nässander U, van Lierop MJ, Bauerschmidt S, Dokter WH, Alkema W. Toonen EJ, et al. Among authors: alkema w. Pharmacogenomics. 2011 Jul;12(7):985-98. doi: 10.2217/pgs.11.34. Epub 2011 Jun 2. Pharmacogenomics. 2011. PMID: 21635145 Clinical Trial.

4

Prednisolone-induced beta cell dysfunction is associated with impaired endoplasmic reticulum homeostasis in INS-1E cells.

Linssen MM, van Raalte DH, Toonen EJ, Alkema W, van der Zon GC, Dokter WH, Diamant M, Guigas B, Ouwens DM. Linssen MM, et al. Among authors: alkema w. Cell Signal. 2011 Nov;23(11):1708-15. doi: 10.1016/j.cellsig.2011.06.002. Epub 2011 Jun 13. Cell Signal. 2011. PMID: 21689745

5

Org 214007-0: a novel non-steroidal selective glucocorticoid receptor modulator with full anti-inflammatory properties and improved therapeutic index.

van Lierop MJ, Alkema W, Laskewitz AJ, Dijkema R, van der Maaden HM, Smit MJ, Plate R, Conti PG, Jans CG, Timmers CM, van Boeckel CA, Lusher SJ, McGuire R, van Schaik RC, de Vlieg J, Smeets RL, Hofstra CL, Boots AM, van Duin M, Ingelse BA, Schoonen WG, Grefhorst A, van Dijk TH, Kuipers F, Dokter WH. van Lierop MJ, et al. Among authors: alkema w. PLoS One. 2012;7(11):e48385. doi: 10.1371/journal.pone.0048385. Epub 2012 Nov 12. PLoS One. 2012. PMID: 23152771 Free PMC article.

6

Identification of new biomarker candidates for glucocorticoid induced insulin resistance using literature mining.

Fleuren WW, Toonen EJ, Verhoeven S, Frijters R, Hulsen T, Rullmann T, van Schaik R, de Vlieg J, Alkema W. Fleuren WW, et al. Among authors: alkema w. BioData Min. 2013 Feb 4;6(1):2. doi: 10.1186/1756-0381-6-2. BioData Min. 2013. PMID: 23379763 Free PMC article.

7

Prednisolone induces the Wnt signalling pathway in 3T3-L1 adipocytes.

Fleuren WW, Linssen MM, Toonen EJ, van der Zon GC, Guigas B, de Vlieg J, Dokter WH, Ouwens DM, Alkema W. Fleuren WW, et al. Among authors: alkema w. Arch Physiol Biochem. 2013 May;119(2):52-64. doi: 10.3109/13813455.2013.774022. Epub 2013 Mar 19. Arch Physiol Biochem. 2013. PMID: 23506355 Free PMC article.

8

Draft Genome Sequence of Lactobacillus delbrueckii subsp. bulgaricus LBB.B5.

Urshev Z, Hajo K, Lenoci L, Bron PA, Dijkstra A, Alkema W, Wels M, Siezen RJ, Minkova S, van Hijum SA. Urshev Z, et al. Among authors: alkema w. Genome Announc. 2016 Oct 6;4(5):e01090-16. doi: 10.1128/genomeA.01090-16. Genome Announc. 2016. PMID: 27795256 Free PMC article.

9

Literature-based compound profiling: application to toxicogenomics.

Frijters R, Verhoeven S, Alkema W, van Schaik R, Polman J. Frijters R, et al. Among authors: alkema w. Pharmacogenomics. 2007 Nov;8(11):1521-34. doi: 10.2217/14622416.8.11.1521. Pharmacogenomics. 2007. PMID: 18034617

10

CoPub: a literature-based keyword enrichment tool for microarray data analysis.

Frijters R, Heupers B, van Beek P, Bouwhuis M, van Schaik R, de Vlieg J, Polman J, Alkema W. Frijters R, et al. Among authors: alkema w. Nucleic Acids Res. 2008 Jul 1;36(Web Server issue):W406-10. doi: 10.1093/nar/gkn215. Epub 2008 Apr 28. Nucleic Acids Res. 2008. PMID: 18442992 Free PMC article.

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