Ndungo E - Search Results

1

Niemann-Pick C1 (NPC1)/NPC1-like1 chimeras define sequences critical for NPC1's function as a flovirus entry receptor.

Krishnan A, Miller EH, Herbert AS, Ng M, Ndungo E, Whelan SP, Dye JM, Chandran K. Krishnan A, et al. Among authors: ndungo e. Viruses. 2012 Oct 25;4(11):2471-84. doi: 10.3390/v4112471. Viruses. 2012. PMID: 23202491 Free PMC article.

2

Ebola virus entry requires the host-programmed recognition of an intracellular receptor.

Miller EH, Obernosterer G, Raaben M, Herbert AS, Deffieu MS, Krishnan A, Ndungo E, Sandesara RG, Carette JE, Kuehne AI, Ruthel G, Pfeffer SR, Dye JM, Whelan SP, Brummelkamp TR, Chandran K. Miller EH, et al. Among authors: ndungo e. EMBO J. 2012 Apr 18;31(8):1947-60. doi: 10.1038/emboj.2012.53. Epub 2012 Mar 6. EMBO J. 2012. PMID: 22395071 Free PMC article.

3

Cell entry by a novel European filovirus requires host endosomal cysteine proteases and Niemann-Pick C1.

Ng M, Ndungo E, Jangra RK, Cai Y, Postnikova E, Radoshitzky SR, Dye JM, Ramírez de Arellano E, Negredo A, Palacios G, Kuhn JH, Chandran K. Ng M, et al. Among authors: ndungo e. Virology. 2014 Nov;468-470:637-646. doi: 10.1016/j.virol.2014.08.019. Epub 2014 Oct 11. Virology. 2014. PMID: 25310500 Free PMC article.

4

Filovirus receptor NPC1 contributes to species-specific patterns of ebolavirus susceptibility in bats.

Ng M, Ndungo E, Kaczmarek ME, Herbert AS, Binger T, Kuehne AI, Jangra RK, Hawkins JA, Gifford RJ, Biswas R, Demogines A, James RM, Yu M, Brummelkamp TR, Drosten C, Wang LF, Kuhn JH, Müller MA, Dye JM, Sawyer SL, Chandran K. Ng M, et al. Among authors: ndungo e. Elife. 2015 Dec 23;4:e11785. doi: 10.7554/eLife.11785. Elife. 2015. PMID: 26698106 Free PMC article.

5

A mutation in the Ebola virus envelope glycoprotein restricts viral entry in a host species- and cell-type-specific manner.

Martinez O, Ndungo E, Tantral L, Miller EH, Leung LW, Chandran K, Basler CF. Martinez O, et al. Among authors: ndungo e. J Virol. 2013 Mar;87(6):3324-34. doi: 10.1128/JVI.01598-12. Epub 2013 Jan 9. J Virol. 2013. PMID: 23302883 Free PMC article.

6

Novel Small Molecule Entry Inhibitors of Ebola Virus.

Basu A, Mills DM, Mitchell D, Ndungo E, Williams JD, Herbert AS, Dye JM, Moir DT, Chandran K, Patterson JL, Rong L, Bowlin TL. Basu A, et al. Among authors: ndungo e. J Infect Dis. 2015 Oct 1;212 Suppl 2(Suppl 2):S425-34. doi: 10.1093/infdis/jiv223. Epub 2015 Jul 22. J Infect Dis. 2015. PMID: 26206510 Free PMC article.

7

Host-Primed Ebola Virus GP Exposes a Hydrophobic NPC1 Receptor-Binding Pocket, Revealing a Target for Broadly Neutralizing Antibodies.

Bornholdt ZA, Ndungo E, Fusco ML, Bale S, Flyak AI, Crowe JE Jr, Chandran K, Saphire EO. Bornholdt ZA, et al. Among authors: ndungo e. mBio. 2016 Feb 23;7(1):e02154-15. doi: 10.1128/mBio.02154-15. mBio. 2016. PMID: 26908579 Free PMC article.

8

A Single Residue in Ebola Virus Receptor NPC1 Influences Cellular Host Range in Reptiles.

Ndungo E, Herbert AS, Raaben M, Obernosterer G, Biswas R, Miller EH, Wirchnianski AS, Carette JE, Brummelkamp TR, Whelan SP, Dye JM, Chandran K. Ndungo E, et al. mSphere. 2016 Mar 30;1(2):e00007-16. doi: 10.1128/mSphere.00007-16. eCollection 2016 Mar-Apr. mSphere. 2016. PMID: 27303731 Free PMC article.

9

Comprehensive functional analysis of N-linked glycans on Ebola virus GP1.

Lennemann NJ, Rhein BA, Ndungo E, Chandran K, Qiu X, Maury W. Lennemann NJ, et al. Among authors: ndungo e. mBio. 2014 Jan 28;5(1):e00862-13. doi: 10.1128/mBio.00862-13. mBio. 2014. PMID: 24473128 Free PMC article.

10

A Novel Shigella Proteome Microarray Discriminates Targets of Human Antibody Reactivity following Oral Vaccination and Experimental Challenge.

Ndungo E, Randall A, Hazen TH, Kania DA, Trappl-Kimmons K, Liang X, Barry EM, Kotloff KL, Chakraborty S, Mani S, Rasko DA, Pasetti MF. Ndungo E, et al. mSphere. 2018 Aug 1;3(4):e00260-18. doi: 10.1128/mSphere.00260-18. mSphere. 2018. PMID: 30068560 Free PMC article.

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