Ohashi PS - Search Results

1

Lysosomal disruption preferentially targets acute myeloid leukemia cells and progenitors.

Sukhai MA, Prabha S, Hurren R, Rutledge AC, Lee AY, Sriskanthadevan S, Sun H, Wang X, Skrtic M, Seneviratne A, Cusimano M, Jhas B, Gronda M, MacLean N, Cho EE, Spagnuolo PA, Sharmeen S, Gebbia M, Urbanus M, Eppert K, Dissanayake D, Jonet A, Dassonville-Klimpt A, Li X, Datti A, Ohashi PS, Wrana J, Rogers I, Sonnet P, Ellis WY, Corey SJ, Eaves C, Minden MD, Wang JC, Dick JE, Nislow C, Giaever G, Schimmer AD. Sukhai MA, et al. Among authors: ohashi ps. J Clin Invest. 2013 Jan;123(1):315-28. doi: 10.1172/JCI64180. Epub 2012 Dec 3. J Clin Invest. 2013. PMID: 23202731 Free PMC article. Clinical Trial.

2

Revised map of the human progenitor hierarchy shows the origin of macrophages and dendritic cells in early lymphoid development.

Doulatov S, Notta F, Eppert K, Nguyen LT, Ohashi PS, Dick JE. Doulatov S, et al. Among authors: ohashi ps. Nat Immunol. 2010 Jul;11(7):585-93. doi: 10.1038/ni.1889. Epub 2010 Jun 13. Nat Immunol. 2010. PMID: 20543838

3

The Src-like adaptor protein regulates GM-CSFR signaling and monocytic dendritic cell maturation.

Liontos LM, Dissanayake D, Ohashi PS, Weiss A, Dragone LL, McGlade CJ. Liontos LM, et al. Among authors: ohashi ps. J Immunol. 2011 Feb 15;186(4):1923-33. doi: 10.4049/jimmunol.0903292. Epub 2011 Jan 10. J Immunol. 2011. PMID: 21220694

4

Immunological perspective of self versus tumor antigens: insights from the RIP-gp model.

Dissanayake D, Gronski MA, Lin A, Elford AR, Ohashi PS. Dissanayake D, et al. Among authors: ohashi ps. Immunol Rev. 2011 May;241(1):164-79. doi: 10.1111/j.1600-065X.2011.01014.x. Immunol Rev. 2011. PMID: 21488897 Review.

5

Different toll-like receptor stimuli have a profound impact on cytokines required to break tolerance and induce autoimmunity.

Lin AC, Dissanayake D, Dhanji S, Elford AR, Ohashi PS. Lin AC, et al. Among authors: ohashi ps. PLoS One. 2011;6(9):e23940. doi: 10.1371/journal.pone.0023940. Epub 2011 Sep 12. PLoS One. 2011. PMID: 21931625 Free PMC article.

6

Nuclear factor-κB1 controls the functional maturation of dendritic cells and prevents the activation of autoreactive T cells.

Dissanayake D, Hall H, Berg-Brown N, Elford AR, Hamilton SR, Murakami K, Deluca LS, Gommerman JL, Ohashi PS. Dissanayake D, et al. Among authors: ohashi ps. Nat Med. 2011 Nov 13;17(12):1663-7. doi: 10.1038/nm.2556. Nat Med. 2011. PMID: 22081022

7

The NF-κB regulator MALT1 determines the encephalitogenic potential of Th17 cells.

Brüstle A, Brenner D, Knobbe CB, Lang PA, Virtanen C, Hershenfield BM, Reardon C, Lacher SM, Ruland J, Ohashi PS, Mak TW. Brüstle A, et al. Among authors: ohashi ps. J Clin Invest. 2012 Dec;122(12):4698-709. doi: 10.1172/JCI63528. Epub 2012 Nov 1. J Clin Invest. 2012. PMID: 23114599 Free PMC article.

8

ARIH2 is essential for embryogenesis, and its hematopoietic deficiency causes lethal activation of the immune system.

Lin AE, Ebert G, Ow Y, Preston SP, Toe JG, Cooney JP, Scott HW, Sasaki M, Saibil SD, Dissanayake D, Kim RH, Wakeham A, You-Ten A, Shahinian A, Duncan G, Silvester J, Ohashi PS, Mak TW, Pellegrini M. Lin AE, et al. Among authors: ohashi ps. Nat Immunol. 2013 Jan;14(1):27-33. doi: 10.1038/ni.2478. Epub 2012 Nov 25. Nat Immunol. 2013. PMID: 23179078

9

Peptide-pulsed dendritic cells have superior ability to induce immune-mediated tissue destruction compared to peptide with adjuvant.

Dissanayake D, Murakami K, Tran MD, Elford AR, Millar DG, Ohashi PS. Dissanayake D, et al. Among authors: ohashi ps. PLoS One. 2014 Mar 19;9(3):e92380. doi: 10.1371/journal.pone.0092380. eCollection 2014. PLoS One. 2014. PMID: 24647761 Free PMC article.

10

miR-155 Upregulation in Dendritic Cells Is Sufficient To Break Tolerance In Vivo by Negatively Regulating SHIP1.

Lind EF, Millar DG, Dissanayake D, Savage JC, Grimshaw NK, Kerr WG, Ohashi PS. Lind EF, et al. Among authors: ohashi ps. J Immunol. 2015 Nov 15;195(10):4632-40. doi: 10.4049/jimmunol.1302941. Epub 2015 Oct 7. J Immunol. 2015. PMID: 26447227

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