Nam S - Search Results

1

Dual inhibition of Janus and Src family kinases by novel indirubin derivative blocks constitutively-activated Stat3 signaling associated with apoptosis of human pancreatic cancer cells.

Nam S, Wen W, Schroeder A, Herrmann A, Yu H, Cheng X, Merz KH, Eisenbrand G, Li H, Yuan YC, Jove R. Nam S, et al. Mol Oncol. 2013 Jun;7(3):369-78. doi: 10.1016/j.molonc.2012.10.013. Epub 2012 Nov 16. Mol Oncol. 2013. PMID: 23206899 Free PMC article.

2

Indirubin derivatives inhibit Stat3 signaling and induce apoptosis in human cancer cells.

Nam S, Buettner R, Turkson J, Kim D, Cheng JQ, Muehlbeyer S, Hippe F, Vatter S, Merz KH, Eisenbrand G, Jove R. Nam S, et al. Proc Natl Acad Sci U S A. 2005 Apr 26;102(17):5998-6003. doi: 10.1073/pnas.0409467102. Epub 2005 Apr 18. Proc Natl Acad Sci U S A. 2005. PMID: 15837920 Free PMC article.

3

Dasatinib (BMS-354825) inhibits Stat5 signaling associated with apoptosis in chronic myelogenous leukemia cells.

Nam S, Williams A, Vultur A, List A, Bhalla K, Smith D, Lee FY, Jove R. Nam S, et al. Mol Cancer Ther. 2007 Apr;6(4):1400-5. doi: 10.1158/1535-7163.MCT-06-0446. Mol Cancer Ther. 2007. PMID: 17431118

4

Activated signal transducers and activators of transcription 3 signaling induces CD46 expression and protects human cancer cells from complement-dependent cytotoxicity.

Buettner R, Huang M, Gritsko T, Karras J, Enkemann S, Mesa T, Nam S, Yu H, Jove R. Buettner R, et al. Among authors: nam s. Mol Cancer Res. 2007 Aug;5(8):823-32. doi: 10.1158/1541-7786.MCR-06-0352. Mol Cancer Res. 2007. PMID: 17699108

5

Novel angiogenesis inhibitory activity in cinnamon extract blocks VEGFR2 kinase and downstream signaling.

Lu J, Zhang K, Nam S, Anderson RA, Jove R, Wen W. Lu J, et al. Among authors: nam s. Carcinogenesis. 2010 Mar;31(3):481-8. doi: 10.1093/carcin/bgp292. Epub 2009 Dec 7. Carcinogenesis. 2010. PMID: 19969552 Free PMC article.

6

Indirubin derivatives induce apoptosis of chronic myelogenous leukemia cells involving inhibition of Stat5 signaling.

Nam S, Scuto A, Yang F, Chen W, Park S, Yoo HS, Konig H, Bhatia R, Cheng X, Merz KH, Eisenbrand G, Jove R. Nam S, et al. Mol Oncol. 2012 Jun;6(3):276-83. doi: 10.1016/j.molonc.2012.02.002. Epub 2012 Feb 17. Mol Oncol. 2012. PMID: 22387217 Free PMC article.

7

Sorafenib inhibits endogenous and IL-6/S1P induced JAK2-STAT3 signaling in human neuroblastoma, associated with growth suppression and apoptosis.

Yang F, Jove V, Buettner R, Xin H, Wu J, Wang Y, Nam S, Xu Y, Ara T, DeClerck YA, Seeger R, Yu H, Jove R. Yang F, et al. Among authors: nam s. Cancer Biol Ther. 2012 May;13(7):534-41. doi: 10.4161/cbt.19603. Epub 2012 May 1. Cancer Biol Ther. 2012. PMID: 22406995 Free article.

8

Novel synthetic derivatives of the natural product berbamine inhibit Jak2/Stat3 signaling and induce apoptosis of human melanoma cells.

Nam S, Xie J, Perkins A, Ma Y, Yang F, Wu J, Wang Y, Xu RZ, Huang W, Horne DA, Jove R. Nam S, et al. Mol Oncol. 2012 Oct;6(5):484-93. doi: 10.1016/j.molonc.2012.05.002. Epub 2012 Jun 2. Mol Oncol. 2012. PMID: 22717603 Free PMC article.

9

A novel 7-bromoindirubin with potent anticancer activity suppresses survival of human melanoma cells associated with inhibition of STAT3 and Akt signaling.

Liu L, Kritsanida M, Magiatis P, Gaboriaud N, Wang Y, Wu J, Buettner R, Yang F, Nam S, Skaltsounis L, Jove R. Liu L, et al. Among authors: nam s. Cancer Biol Ther. 2012 Nov;13(13):1255-61. doi: 10.4161/cbt.21781. Epub 2012 Aug 16. Cancer Biol Ther. 2012. PMID: 22895078 Free PMC article.

10

Spirooxindole derivative SOID-8 induces apoptosis associated with inhibition of JAK2/STAT3 signaling in melanoma cells.

Tian Y, Nam S, Liu L, Yakushijin F, Yakushijin K, Buettner R, Liang W, Yang F, Ma Y, Horne D, Jove R. Tian Y, et al. Among authors: nam s. PLoS One. 2012;7(11):e49306. doi: 10.1371/journal.pone.0049306. Epub 2012 Nov 16. PLoS One. 2012. PMID: 23166634 Free PMC article.

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