Wen W - Search Results

1

Dual inhibition of Janus and Src family kinases by novel indirubin derivative blocks constitutively-activated Stat3 signaling associated with apoptosis of human pancreatic cancer cells.

Nam S, Wen W, Schroeder A, Herrmann A, Yu H, Cheng X, Merz KH, Eisenbrand G, Li H, Yuan YC, Jove R. Nam S, et al. Among authors: wen w. Mol Oncol. 2013 Jun;7(3):369-78. doi: 10.1016/j.molonc.2012.10.013. Epub 2012 Nov 16. Mol Oncol. 2013. PMID: 23206899 Free PMC article.

2

Antitumor activity of targeting SRC kinases in endothelial and myeloid cell compartments of the tumor microenvironment.

Liang W, Kujawski M, Wu J, Lu J, Herrmann A, Loera S, Yen Y, Lee F, Yu H, Wen W, Jove R. Liang W, et al. Among authors: wen w. Clin Cancer Res. 2010 Feb 1;16(3):924-35. doi: 10.1158/1078-0432.CCR-09-1486. Epub 2010 Jan 26. Clin Cancer Res. 2010. PMID: 20103658 Free PMC article.

3

MLS-2384, a new 6-bromoindirubin derivative with dual JAK/Src kinase inhibitory activity, suppresses growth of diverse cancer cells.

Liu L, Gaboriaud N, Vougogianopoulou K, Tian Y, Wu J, Wen W, Skaltsounis L, Jove R. Liu L, et al. Among authors: wen w. Cancer Biol Ther. 2014 Feb;15(2):178-84. doi: 10.4161/cbt.26721. Epub 2013 Nov 1. Cancer Biol Ther. 2014. PMID: 24100507 Free PMC article.

4

Synergistic anti-tumor effect of combined inhibition of EGFR and JAK/STAT3 pathways in human ovarian cancer.

Wen W, Wu J, Liu L, Tian Y, Buettner R, Hsieh MY, Horne D, Dellinger TH, Han ES, Jove R, Yim JH. Wen W, et al. Mol Cancer. 2015 May 1;14:100. doi: 10.1186/s12943-015-0366-5. Mol Cancer. 2015. PMID: 25928246 Free PMC article.

5

Novel angiogenesis inhibitory activity in cinnamon extract blocks VEGFR2 kinase and downstream signaling.

Lu J, Zhang K, Nam S, Anderson RA, Jove R, Wen W. Lu J, et al. Among authors: wen w. Carcinogenesis. 2010 Mar;31(3):481-8. doi: 10.1093/carcin/bgp292. Epub 2009 Dec 7. Carcinogenesis. 2010. PMID: 19969552 Free PMC article.

6

Bortezomib induces apoptosis and growth suppression in human medulloblastoma cells, associated with inhibition of AKT and NF-ĸB signaling, and synergizes with an ERK inhibitor.

Yang F, Jove V, Chang S, Hedvat M, Liu L, Buettner R, Tian Y, Scuto A, Wen W, Yip ML, Van Meter T, Yen Y, Jove R. Yang F, et al. Among authors: wen w. Cancer Biol Ther. 2012 Apr;13(6):349-57. doi: 10.4161/cbt.19239. Epub 2012 Apr 1. Cancer Biol Ther. 2012. PMID: 22313636 Free PMC article.

7

Targeting JAK1/STAT3 signaling suppresses tumor progression and metastasis in a peritoneal model of human ovarian cancer.

Wen W, Liang W, Wu J, Kowolik CM, Buettner R, Scuto A, Hsieh MY, Hong H, Brown CE, Forman SJ, Horne D, Morgan R, Wakabayashi M, Dellinger TH, Han ES, Yim JH, Jove R. Wen W, et al. Mol Cancer Ther. 2014 Dec;13(12):3037-48. doi: 10.1158/1535-7163.MCT-14-0077. Epub 2014 Oct 15. Mol Cancer Ther. 2014. PMID: 25319391 Free PMC article.

8

Increasing Antitumor Activity of JAK Inhibitor by Simultaneous Blocking Multiple Survival Signaling Pathways in Human Ovarian Cancer.

Wen W, Han ES, Dellinger TH, Wu J, Guo Y, Buettner R, Horne DA, Jove R, Yim JH. Wen W, et al. Transl Oncol. 2019 Aug;12(8):1015-1025. doi: 10.1016/j.tranon.2019.05.003. Epub 2019 May 26. Transl Oncol. 2019. PMID: 31141756 Free PMC article.

9

Cinnamon extract reduces VEGF expression via suppressing HIF-1α gene expression and inhibits tumor growth in mice.

Zhang K, Han ES, Dellinger TH, Lu J, Nam S, Anderson RA, Yim JH, Wen W. Zhang K, et al. Among authors: wen w. Mol Carcinog. 2017 Feb;56(2):436-446. doi: 10.1002/mc.22506. Epub 2016 Jun 15. Mol Carcinog. 2017. PMID: 27253180 Free PMC article.

10

Ruxolitinib synergistically enhances the anti-tumor activity of paclitaxel in human ovarian cancer.

Han ES, Wen W, Dellinger TH, Wu J, Lu SA, Jove R, Yim JH. Han ES, et al. Among authors: wen w. Oncotarget. 2018 Jan 31;9(36):24304-24319. doi: 10.18632/oncotarget.24368. eCollection 2018 May 11. Oncotarget. 2018. PMID: 29849942 Free PMC article.

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